Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Toshiro Hamamoto"'
Autor:
Tohru Matsuura, Hitoshi Endo, Kenji Kuroiwa, Katsumi Kasashima, Takafumi Mashiko, Yasuyuki Nozaki, Eiji Sakashita, Kaoru Tominaga, Toshiro Hamamoto
Publikováno v:
The Journal of biological chemistry. 291(29)
Cytoplasmic protein aggregates are one of the pathological hallmarks of neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). Several RNA-binding proteins have been identified as comp
Autor:
Toshio Mori, Shiro Amano, Taeko Inoki, Toshiro Hamamoto, Satoru Yamagami, Yutaka Inoki, Kazunori Miyata, Hitoshi Endo, Tadahiko Tsuru
Publikováno v:
Experimental Eye Research. 79:367-376
Purpose . To determine damaged DNA-binding protein 2-gene expression levels in vitro and ex vivo, and the degree of DNA repair in damaged DNA-binding protein 2-overexpressing cultured human corneal endothelium after ultraviolet irradiation. Methods .
Autor:
Yasuo Kagawa, Toshiro Hamamoto, Taeko Inoki, Satoru Yamagami, Hitoshi Endo, Toshio Mori, Yutaka Inoki, Tadahiko Tsuru
Publikováno v:
Biochemical and Biophysical Research Communications. 314:1036-1043
Damaged DNA-binding protein (DDB) is a heterodimer (DDB1 and DDB2), which is implicated in the repair of UV-irradiated DNA damage. Here we have identified four DDB2 variants from HeLa cells (D1-D4) that are generated by alternative splicing. Analysis
Autor:
Akihiko Tokue, Hitoshi Endo, Masaki Baba, Shoji Yamazaki, Toshiro Hamamoto, Toru Okuyama, Yoshiko Joichi, Sanae Kaneko, Tatuo Morita, Hoyoku Nishino, Yoshihito Okada
Publikováno v:
Cancer Letters. 183:23-30
Isoliquiritigenin is a chalcone isolated from licorice and shallots. The ability of isoliquiritigenin to suppress metastasis was examined in a pulmonary metastasis model of mouse renal cell carcinoma. Isoliquiritigenin significantly reduced pulmonary
Muscle-specific Exonic Splicing Silencer for Exon Exclusion in Human ATP Synthase γ-Subunit Pre-mRNA
Autor:
Toshiro Hamamoto, Yasuo Kagawa, Eiji Sakashita, Hitoshi Endo, Shin-ichi Tominaga, Eriko Ueno, Morisada Hayakawa
Publikováno v:
Journal of Biological Chemistry. 277:6974-6984
Mitochondrial ATP synthase gamma-subunit (F(1)gamma) pre-mRNA undergoes alternative splicing in a tissue- or cell type-specific manner. Exon 9 of F(1)gamma pre-mRNA is specifically excluded in heart and skeletal muscle tissues and in acid-stimulated
Autor:
Yoji Hakamata, Yasuo Kagawa, Shoji Yamazaki, Hitoshi Endo, Tadatoshi Kinouchi, Yutaka Inoki, Toshiro Hamamoto
Publikováno v:
Biochemical and Biophysical Research Communications. 278:183-191
Colocalization of mitochondria is the first step of intermitochondrial interaction or fusion in a cell. Here, we showed colocalization between exogenous mitochondria and endogenous ones or between exogenous proteoliposomes and endogenous mitochondria
Autor:
Shou Takashima, Shin-Ichiro Nishimura, Mari Kono, Shunichiro Ogata, Hong Liu, Shuichi Tsuji, Tetsuro Tsuda, Toshiro Hamamoto, Steven H. Itzkowitz
Publikováno v:
Biochemical and Biophysical Research Communications. 272:94-97
The acceptor substrate specificities of ST6GalNAc I and II, which act on the synthesis of O-linked oligosaccharides, were reexamined using ovine submaxillary mucin, [Ala-Thr(GalNAc)-Ala] n polymer ( n = 7–11). It has been suggested that only ST6Gal
Autor:
Yasuo Kagawa, Hitoshi Endo, Toshiro Hamamoto, Masaru Ichida, Yoji Hakamata, Kazuyuki Shimada, Morisada Hayakawa, Uichi Ikeda, Eriko Ueno
Publikováno v:
Journal of Biological Chemistry. 275:15992-16001
Muscle-specific isoform of the mitochondrial ATP synthase gamma subunit (F(1)gamma) was generated by alternative splicing, and exon 9 of the gene was found to be lacking particularly in skeletal muscle and heart tissue. Recently, we reported that alt
Publikováno v:
Journal of Bioenergetics and Biomembranes. 32:471-484
ATP synthase (FoF1) consists of F1 (ATP-driven motor) and Fo (H+-driven motor). F1 is a complex of α3β3γδe subunits, and γ is the rotating cam in α3β3. Thermophilic F1 (TF1) is exceptional in that it can be crystallized as a β monomer and an
Publikováno v:
Biochemical and Biophysical Research Communications. 266:662-676
Recent advances in bioenergetics consist of discoveries related to rotational coupling in ATP synthase (FoF(1)), uncoupling proteins (UCP), reactive oxygen species (ROS) and mitochondrial DNA (mtDNA). As shown in cloned sheep, mammalian genomes are c