Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Toshiro Fukushima"'
Publikováno v:
Toxicology Reports, Vol 10, Iss , Pp 281-292 (2023)
It has previously been found that, compared with cigarette smoke, the aerosols generated by heated tobacco products contain fewer and lower harmful and potentially harmful constituents (HPHCs) and elicit lower biological activity in in vitro models a
Externí odkaz:
https://doaj.org/article/49f4217e4cff437da32933ec0e8a3c43
Autor:
Jacqueline Miller-Holt, Irene Baskerville-Abraham, Masanori Sakimura, Toshiro Fukushima, Andrea Puglisi, Jeremie Gafner
Publikováno v:
Toxicology Reports, Vol 9, Iss , Pp 1316-1324 (2022)
Non-clinical in vitro studies were conducted to investigate the characteristics of extracts from tobacco free nicotine pouches alongside a reference snus product and/or 1R6F reference cigarette. In vitro investigations were conducted in the Neutral R
Externí odkaz:
https://doaj.org/article/01215efe72b74725bc79f9c473cb1abd
Autor:
Masayuki Kato, Kei-ichi Sugiyama, Toshiro Fukushima, Yasuyoshi Miura, Takumi Awogi, Shigetomo Hikosaka, Kumiko Kawakami, Madoka Nakajima, Masato Nakamura, Hajime Sui, Kumiko Watanabe, Atsushi Hakura
Publikováno v:
Genes and Environment, Vol 40, Iss 1, Pp 1-13 (2018)
Abstract A large-scale study was conducted by multiple laboratories affiliated with the Japanese Environmental Mutagen Society and the Bacterial Mutagenicity Study Group to investigate possible proficiency indicators for the bacterial reverse mutatio
Externí odkaz:
https://doaj.org/article/0d3a2bfc233041b89a8cb8cb76e2bf8e
Autor:
Munehisa Kito, Tomonobu Koizumi, Shunichiro Matsuoka, Sachie Koike, Takashi Eguchi, Tsutomu Koyama, Takeshi Uehara, Tetsu Takeda, Toshiro Fukushima, Jun Takahashi, Kentaro Miura, Kimihiro Shimizu, Hiromasa Hasegawa, Kazutoshi Hamanaka
Publikováno v:
Journal of Hard Tissue Biology. 30:309-316
Autor:
Tomohiro Takahashi, Yuka Sakai, Miyuki Yanagimachi, Kaori Shibuya, Asami Kumagai, Shigeaki Ito, Toshiro Fukushima, Shinkichi Ishikawa, Sakura Mori
Publikováno v:
Beiträge zur Tabakforschung International, Vol 29, Iss 3, Pp 119-135 (2020)
Summary A new reference cigarette, 1R6F, produced by the Kentucky Tobacco Research and Development Center, has been manufactured as a substitute for the 3R4F reference cigarette because of a depletion of 3R4F stock. The purpose of the current study w
Autor:
Robert Leverette, Betsy Bombick, Roman Wieczorek, Xiang Li, Kei Yoshino, David Thorne, Toshiro Fukushima, Han-Jae Shin, Mark Ballantyne
Publikováno v:
Toxicology Research and Application, Vol 5 (2021)
During a Cooperation Centre for Scientific Research Relative to Tobacco (CORESTA) meeting, the in vitro toxicity testing Sub-Group (IVT SG) met to discuss the evolving field of aerosol exposure research. Given the diversity of exposure parameters and
Publikováno v:
Mutation research. Genetic toxicology and environmental mutagenesis. 873
We have compared micronucleus (MN) induction by cigarette smoke in the L5178Y, TK6, and CHL/IU cell lines. The test sample was total particulate matter of 3R4F reference cigarette smoke, suspended in DMSO. After 3-h treatment, with or without a rat l
Autor:
Hinako, Kato, Toshiro, Fukushima, Takashi, Kobayashi, Nodoka, Sekiguchi, Shintaro, Kanda, Tomonobu, Koizumi
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 47(10)
A 22-year-old male was diagnosed with a metastatic nonseminomatous germ cell tumor in the mediastinum with an elevated serum alpha-fetoprotein(AFP)concentration. Histopathological findings following percutaneous biopsy revealed the presence of a matu
Autor:
Toshiro Fukushima, Yuki Kanemaru, Kentaro Eguchi, Shinya Yoshida, Yasunori Takahashi, Ian Jones, Jacqueline Miller-Holt
Publikováno v:
Regulatory Toxicology and Pharmacology. 92:94-103
The recent rapid increase in the prevalence of emerging tobacco- and nicotine-containing products, such as e-cigarettes, is being driven in part by their reduced-risk potential compared to tobacco smoking. In this study, we examined emission levels f
Autor:
Hiroaki, Watanabe, Akira, Mimura, Toshiro, Fukushima, Takuro, Noguchi, Takesumi, Ozawa, Takashi, Kobayashi, Nodoka, Sekiguchi, Shigeru, Ohmori, Tomonobu, Koizumi
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 46(5)
We encountered 2 cases of T790M-positive non-small cell lung cancer in patients who developed toxic erythema within a week after initiation of osimertinib(80mg/day)therapy. Since osimertinib was regarded as the suspected drug, we adminis- tered desen