Zobrazeno 1 - 10
of 1 208
pro vyhledávání: '"Toshiro, Fujita"'
Autor:
Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Wakako Kawarazaki, Shigeyoshi Oba, Takeshi Marumo, Atsu Aiba, Toshiro Fujita
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Development of the renal medulla continues after birth to form mature renal papilla and obtain urine-concentrating ability. Here, we found that a small GTPase, Rac1, plays a critical role in the postnatal development of renal papilla. Mice w
Externí odkaz:
https://doaj.org/article/7d062fbbc6354111a603190990e4d407
Autor:
Takeshi Marumo, Wakako Kawarazaki, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa, Daigoro Hirohama, Toshikazu Okaneya, Kazunari Yuki, Yoshihito Atsumi, Atsuhisa Sato, Eri Arai, Yae Kanai, Tatsuo Shimosawa, Toshiro Fujita
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 8, Iss 1 (2020)
Introduction Renal tubular injury contributes to the decline in kidney function in patients with diabetes. Cell type-specific DNA methylation patterns have been used to calculate proportions of particular cell types. In this study, we developed a met
Externí odkaz:
https://doaj.org/article/108e46a7319944d8a35687fd997ea66e
Autor:
Shigeyoshi Oba, Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Wakako Kawarazaki, Kohei Ueda, Daigoro Hirohama, Fumiko Kawakami-Mori, Tatsuo Shimosawa, Takeshi Marumo, Toshiro Fujita
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Abstract Epigenetic modulation may underlie the progression of diabetic nephropathy (DN). Involvement of TGFB1 in mesangial fibrosis of DN led us to hypothesize that Tgfb1 DNA demethylation contributes to progression of DN. In primary mesangial cells
Externí odkaz:
https://doaj.org/article/25e25c0186854cdaaea68a964729952f
Autor:
Shigeru Shibata, Kenichi Ishizawa, Qin Wang, Ning Xu, Toshiro Fujita, Shunya Uchida, Richard P. Lifton
Publikováno v:
Cell Reports, Vol 24, Iss 3, Pp 569-576 (2018)
Summary: Mineralocorticoid receptor (MR) signaling regulates both renal Na-Cl reabsorption and K+ excretion. We previously demonstrated that phosphorylation of S843 in the MR ligand-binding domain in renal intercalated cells is involved in the balanc
Externí odkaz:
https://doaj.org/article/28b30e35d06a4e33a48dd7c2edee0e8c
Publikováno v:
Revista Ibero-Americana de Humanidades, Ciências e Educação. 8:69-87
Esse artigo buscou descrever a utilização da odontologia legal na identificação de vítimas em desastres por meio de uma busca seletiva em banco de dados sobre o tema escolhido através de uma revisão.Para a coleta de dados, foi realizada uma bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea692dff28595e174332df8efaac1f16
https://doi.org/10.51891/rease.v8i11.7577
https://doi.org/10.51891/rease.v8i11.7577
Autor:
Toshikazu KURANOUCHI, Akiko TAKADA, Toshiro FUJITA, Kenji KATAYAMA, Mio NISHINAKA, Kazunori TAGUCHI
Publikováno v:
Root Research. 31:83-89
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d960df5b1c471948205e5eb0fc8b215
https://doi.org/10.3117/rootres.31.83
https://doi.org/10.3117/rootres.31.83
Publikováno v:
AIJ Journal of Technology and Design. 28:627-630
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c5c637cb7556f838e9cccf7741da7be
https://doi.org/10.3130/aijt.28.627
https://doi.org/10.3130/aijt.28.627
Autor:
Koshu Okubo, Mako Kamiya, Yasuteru Urano, Hiroshi Nishi, Jan M. Herter, Tanya Mayadas, Daigoro Hirohama, Kazuo Suzuki, Hiroshi Kawakami, Mototsugu Tanaka, Miho Kurosawa, Shinji Kagaya, Keiichi Hishikawa, Masaomi Nangaku, Toshiro Fujita, Matsuhiko Hayashi, Junichi Hirahashi
Publikováno v:
EBioMedicine, Vol 10, Iss C, Pp 204-215 (2016)
Neutrophils are central players in the innate immune system. They generate neutrophil extracellular traps (NETs), which protect against invading pathogens but are also associated with the development of autoimmune and/or inflammatory diseases and thr
Externí odkaz:
https://doaj.org/article/e0ab3864351b42569f8d92f288f0f789
Autor:
Toshiro Fujita
Publikováno v:
Hypertension.
This review highlights recent insights into the epigenetic mechanism of salt-sensitive hypertension from the fetus to the elderly population, mainly focusing on the DNA methylation and histone modification-mediated regulation of hypertension-associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb30f01004e81b0ea0f3a798550c316
https://doi.org/10.1161/hypertensionaha.122.20588
https://doi.org/10.1161/hypertensionaha.122.20588
Autor:
Daigoro Hirohama, Shigeyoshi Oba, Mitsuhiro Nishimoto, Wataru Fujii, Shigeru Shibata, Wakako Kawarazaki, Toshiro Fujita, Nobuhiro Ayuzawa, Takeshi Marumo
Publikováno v:
Hypertension. 78:82-93
The progression of diabetic kidney disease (DKD), a leading cause of end-stage kidney disease, involves mineralocorticoid receptor (MR) activation. We previously identified crosstalk between the small guanosine triphosphatase (GTPase) RAS-related C3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bda3bf340c9906854a781d9be240bdd
https://doi.org/10.1161/hypertensionaha.121.17263
https://doi.org/10.1161/hypertensionaha.121.17263