Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Toshio Watanuki"'
Autor:
Hirotaka Yamagata, Shusaku Uchida, Koji Matsuo, Kenichiro Harada, Ayumi Kobayashi, Mami Nakashima, Masayuki Nakano, Koji Otsuki, Naoko Abe-Higuchi, Fumihiro Higuchi, Toshio Watanuki, Toshio Matsubara, Shigeo Miyata, Masato Fukuda, Masahiko Mikuni, Yoshifumi Watanabe
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract The heterogeneity of depression (due to factors such as varying age of onset) may explain why biological markers of major depressive disorder (MDD) remain uncertain. We aimed to identify gene expression markers of MDD in leukocytes using mic
Externí odkaz:
https://doaj.org/article/fa368dc39a86472c99c7fb99caf1454b
Autor:
Kenichiro Harada, Toshikazu Ikuta, Mami Nakashima, Toshio Watanuki, Masako Hirotsu, Toshio Matsubara, Hirotaka Yamagata, Yoshifumi Watanabe, Koji Matsuo
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Patients with later-life depression (LLD) show abnormal gray matter (GM) volume, white matter (WM) integrity and functional connectivity in the anterior cingulate cortex (ACC) and posterior superior temporal gyrus (pSTG), but it remains unclear wheth
Externí odkaz:
https://doaj.org/article/8de90c75519645ef83a81269af783d6d
Disconnectivity between Dorsal Raphe Nucleus and Posterior Cingulate Cortex in Later Life Depression
Autor:
Toshikazu Ikuta, Koji Matsuo, Kenichiro Harada, Mami Nakashima, Teruyuki Hobara, Naoko Higuchi, Fumihiro Higuchi, Koji Otsuki, Tomohiko Shibata, Toshio Watanuki, Toshio Matsubara, Hirotaka Yamagata, Yoshifumi Watanabe
Publikováno v:
Frontiers in Aging Neuroscience, Vol 9 (2017)
The dorsal raphe nucleus (DRN) has been repeatedly implicated as having a significant relationship with depression, along with its serotoninergic innervation. However, functional connectivity of the DRN in depression is not well understood. The curre
Externí odkaz:
https://doaj.org/article/8cc8b6b236cc4fc6bbf213fccd9c501c
Autor:
Toshio Matsubara, Koji Matsuo, Kenichiro Harada, Masayuki Nakano, Mami Nakashima, Toshio Watanuki, Kazuteru Egashira, Matakazu Furukawa, Naofumi Matsunaga, Yoshifumi Watanabe
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168493 (2016)
Little is known about disorder-specific biomarkers of bipolar disorder (BD) and major depressive disorder (MDD). Our aim was to determine a neural substrate that could be used to distinguish BD from MDD. Our study included a BD group (10 patients wit
Externí odkaz:
https://doaj.org/article/06156b4132f24e78b3a4771ee6082c07
Autor:
Hidenori Harada, Hironori Izumi, Shu Tahara, Aki Mori, Toshihiko Taguchi, Hiroyoshi Ogasa, Hidenori Suzuki, Kazusige Seki, Fumihiro Higuchi, Toshio Watanuki
Publikováno v:
PAIN RESEARCH. 33:220-224
Autor:
Hirotaka Yamagata, Toshio Watanuki, Fumihiro Higuchi, Toshio Matsubara, Yoshifumi Watanabe, Koji Matsuo, Mami Nakashima, Ayumi Kobayashi, Shusaku Uchida, Kenichiro Harada
Publikováno v:
Journal of Affective Disorders. 233:79-85
Background Glycosylation is a common posttranslational modification in protein biosynthesis that is implicated in several disease states. It has been reported that specific protein glycan structures are useful as biomarkers for cancer and some neurop
Autor:
Toshio Matsubara, Koji Matsuo, Kenichiro Harada, Masako Hirotsu, Yoichi Kaku, Shinji Isomura, Yoshifumi Watanabe, Mami Nakashima, Keiko Hirata, Kazuteru Egashira, Toshio Watanuki, Hiroshi Kaneyuki
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
Although literature evidence suggests deficits in social and non-social cognition in patients with autistic spectrum disorder (ASD) and schizophrenia (SCZ), the difference in neural correlates of the impairments between the two disorders has not been
Autor:
Toshio Watanuki, Yoshifumi Watanabe, Toshio Matsubara, Chong Chen, Shin Nakagawa, Koji Matsuo, Masako Hirotsu
Publikováno v:
Biological Psychiatry. 87:S349-S350
Autor:
Mami Nakashima, Tomohiko Shibata, Kenichiro Harada, Yoshifumi Watanabe, Fumihiro Higuchi, Keigo Shimoji, Naoko Higuchi, Teruyuki Hobara, Hirotaka Yamagata, Masayuki Nakano, Toshio Matsubara, Koji Matsuo, Yusuke Fujita, Toshio Watanuki, Koji Otsuki
Publikováno v:
Journal of Affective Disorders. 204:112-119
Background Depression in old age is an increasing contributor to poor health and accompanying health care costs. Although there is an abundance of literature on later-life depression (LLD), the neural correlates have not been clarified. The aim of th
Autor:
Toshio Matsubara, Koji Matsuo, Yoshifumi Watanabe, Takahashi K, Kazuteru Egashira, Kenichiro Harada, Mami Nakashima, Masayuki Nakano, Toshio Watanuki
Publikováno v:
Schizophrenia Research. 170:109-114
Although patients with schizophrenia demonstrate abnormal processing of emotional face recognition, the neural substrates underlying this process remain unclear. We previously showed abnormal fronto-temporal function during facial expression of emoti