Výsledky vyhledávání - "Toshio SAKIYAMA"

Expression of glycoprotein nonmetastatic melanoma protein B in macrophages infiltrating injured mucosa is associated with the severity of experimental colitis in mice

Autor: Shuji Kanmura, Kazuaki Tabu, Akio Ido, Yuichro Nasu, Kotaro Kumagai, Masatsugu Numata, Takeshi Kure, Fumisato Sasaki, Yoichiro Takami, Hirofumi Uto, Shinichi Hashimoto, Hirohito Tsubouchi, Akihiro Moriuchi, Toshio Sakiyama

Publikováno v: Molecular Medicine Reports. 12:7503-7511

Glycoprotein nonmetastatic melanoma protein B (Gpnmb) is a transmembrane glycoprotein, which negatively regulates the inflammatory responses of macrophages. However, the role of Gpnmb in intestinal macrophages remains to be fully elucidated. The pres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d89dafd816c9282aa0b0ad3d587af747
https://doi.org/10.3892/mmr.2015.4408

Zobrazit plný text záznamu

Human neutrophil peptides induce interleukin-8 in intestinal epithelial cells through the P2 receptor and ERK1/2 signaling pathways

Autor: Akio Ido, Kazunari Ibusuki, Hirofumi Uto, Masatsugu Numata, Takuro Maeda, Yuji Iwashita, Hirohito Tsubouchi, Yuichiro Nasu, Shuji Kanmura, Shinichi Hashimoto, Toshio Sakiyama, Hiroki Taguchi, Fumisato Sasaki

Publikováno v: International Journal of Molecular Medicine. 35:1603-1609

Human neutrophil peptides (HNPs) are antimicrobial peptides produced predominantly by neutrophils. We have previously reported that HNP 1-3 levels are increased in the sera and plasma of patients with active ulcerative colitis. The increased expressi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf60f6ad64decbc9b1fc31cbbba7cb0
https://doi.org/10.3892/ijmm.2015.2156

Zobrazit plný text záznamu

Butyrate and bioactive proteolytic form of Wnt-5a regulate colonic epithelial proliferation and spatial development

Autor: Bana Jabri, Yoshito Itoh, Thaddeus S. Stappenbeck, Kazuhiko Uchiyama, Yasushi Nakagawa, Toshikazu Yoshikawa, Hiroyuki Miyoshi, Tong-Chuan He, Mark W. Musch, Toshio Sakiyama, Takumu Hasebe, Eugene B. Chang, Yuji Naito, Lev Lichtenstein

Publikováno v: Scientific Reports

Proliferation and spatial development of colonic epithelial cells are highly regulated along the crypt vertical axis, which, when perturbed, can result in aberrant growth and carcinogenesis. In this study, two key factors were identified that have im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8aa180f1d2569184bd58e39d4320daf
http://europepmc.org/articles/PMC4999796

Zobrazit plný text záznamu

[Jejunal duplication in an adult presenting with hematochezia]

Autor: Kazuhiko, Inoue, Toshio, Sakiyama, Kanae, Setoyama, Yuji, Iwashita, Seiya, Saito, Norihisa, Hanada, Yoshihiro, Komohara, Fumisato, Sasaki, Masatsugu, Numata, Akio, Ido

Publikováno v: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology. 113(4)

A 56-year-old man was admitted to our hospital with appetite loss, palpitations, orthostatic syncope, and hematochezia. Contrast-enhanced abdominal computed tomography (CT) revealed a proximal jejunal diverticulum with contrast extravasation. We imme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::01f7bb617927e6bcc4ed10b9f839f54b
https://pubmed.ncbi.nlm.nih.gov/27052396

Zobrazit plný text záznamu

Polyamines mediate glutamine-dependent induction of the intestinal epithelial heat shock response

Autor: Yuji Iwashita, Hirohito Tsubouchi, Mark W. Musch, Mark J. Ropeleski, Toshio Sakiyama, Eugene B. Chang

Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology. 301:G181-G187

Heat shock proteins (Hsps) are highly conserved proteins that play a role in cytoprotection and maintaining intestinal homeostasis. Glutamine is essential for the optimal induction of intestinal epithelial Hsp expression, but its mechanisms of action

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519dda3fa8b667462159ce1c02cffc1e
https://doi.org/10.1152/ajpgi.00054.2011

Zobrazit plný text záznamu

Liver regeneration after partial hepatectomy in rat is more impaired in a steatotic liver induced by dietary fructose compared to dietary fat

Autor: Shirou Tanoue, Shinichi Hashimoto, Yuichiro Nasu, Shiho Arima, Makoto Oketani, Yoichiro Takami, Hirofumi Uto, Toshio Sakiyama, Hirohito Tsubouchi, Akihiro Moriuchi, Ryo Kumamoto, Akio Ido

Publikováno v: Biochemical and Biophysical Research Communications. 407:163-168

Hepatic steatosis (HS) has a negative effect on liver regeneration, but different pathophysiologies of HS may lead to different outcomes. Male Sprague-Dawley rats were fed a high fructose (66% fructose; H-fruc), high fat (54% fat; H-fat), or control

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e70f3d931c9d4462530f007a87510208
https://doi.org/10.1016/j.bbrc.2011.02.131

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání