Zobrazeno 1 - 10 of 65 pro vyhledávání: '"Toshio Ota"'
1
Akademický článek
Event-Related Alpha-Band Power Changes During Self-reflection and Working Memory Tasks in Healthy Individuals
Autor: Takahiro Matsuoka, Takaki Shimode, Toshio Ota, Koji Matsuo
Publikováno v: Frontiers in Human Neuroscience, Vol 14 (2021)
Dysfunctional attentional control is observed in patients with mental disorders. However, there is no established neurophysiological method to assess attention in such patients. We showed a discrepancy in alpha-band power in the tasks that evoked int
Externí odkaz: https://doaj.org/article/32d9a8a21ccb41f68aa839995ca90362
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2
Akademický článek
Preclinical and phase I clinical studies of KW-2450, a dual IGF-1R/IR tyrosine kinase inhibitor, in combination with lapatinib and letrozole
Autor: Hiroshi Umehara, Yoshimi Maekawa, Fumito Koizumi, Makiko Shimizu, Toshio Ota, Tamer M. Fouad, Jie Willey, Hidekuni Kaito, Norihiko Shiraishi, Daisuke Nakashima, Shiro Akinaga, Naoto T. Ueno
Publikováno v: Therapeutic Advances in Medical Oncology, Vol 10 (2018)
Background: KW-2450 is an oral dual insulin-like growth factor-1 receptor/insulin receptor tyrosine kinase inhibitor. We investigated the in vitro and in vivo preclinical activity of KW-2450 plus lapatinib and letrozole and conducted a phase I trial
Externí odkaz: https://doaj.org/article/e78fa8802280460695e1175fa5a25353
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4
Akademický článek
Overexpression of chitinase 3-like 1/YKL-40 in lung-specific IL-18-transgenic mice, smokers and COPD.
Autor: Yuki Sakazaki, Tomoaki Hoshino, Satoko Takei, Masanori Sawada, Hanako Oda, Shin-ichi Takenaka, Haruki Imaoka, Kazuko Matsunaga, Toshio Ota, Yuzuru Abe, Ichiro Miki, Kiminori Fujimoto, Tomotaka Kawayama, Seiya Kato, Hisamichi Aizawa
Publikováno v: PLoS ONE, Vol 6, Iss 9, p e24177 (2011)
We analyzed the lung mRNA expression profiles of a murine model of COPD developed using a lung-specific IL-18-transgenic mouse. In this transgenic mouse, the expression of 608 genes was found to vary more than 2-fold in comparison with control WT mic
Externí odkaz: https://doaj.org/article/957f5d207e5a498c81024d2359bfebd7
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5
Akademický článek
Integrative annotation of 21,037 human genes validated by full-length cDNA clones.
Autor: Tadashi Imanishi, Takeshi Itoh, Yutaka Suzuki, Claire O'Donovan, Satoshi Fukuchi, Kanako O Koyanagi, Roberto A Barrero, Takuro Tamura, Yumi Yamaguchi-Kabata, Motohiko Tanino, Kei Yura, Satoru Miyazaki, Kazuho Ikeo, Keiichi Homma, Arek Kasprzyk, Tetsuo Nishikawa, Mika Hirakawa, Jean Thierry-Mieg, Danielle Thierry-Mieg, Jennifer Ashurst, Libin Jia, Mitsuteru Nakao, Michael A Thomas, Nicola Mulder, Youla Karavidopoulou, Lihua Jin, Sangsoo Kim, Tomohiro Yasuda, Boris Lenhard, Eric Eveno, Yoshiyuki Suzuki, Chisato Yamasaki, Jun-ichi Takeda, Craig Gough, Phillip Hilton, Yasuyuki Fujii, Hiroaki Sakai, Susumu Tanaka, Clara Amid, Matthew Bellgard, Maria de Fatima Bonaldo, Hidemasa Bono, Susan K Bromberg, Anthony J Brookes, Elspeth Bruford, Piero Carninci, Claude Chelala, Christine Couillault, Sandro J de Souza, Marie-Anne Debily, Marie-Dominique Devignes, Inna Dubchak, Toshinori Endo, Anne Estreicher, Eduardo Eyras, Kaoru Fukami-Kobayashi, Gopal R Gopinath, Esther Graudens, Yoonsoo Hahn, Michael Han, Ze-Guang Han, Kousuke Hanada, Hideki Hanaoka, Erimi Harada, Katsuyuki Hashimoto, Ursula Hinz, Momoki Hirai, Teruyoshi Hishiki, Ian Hopkinson, Sandrine Imbeaud, Hidetoshi Inoko, Alexander Kanapin, Yayoi Kaneko, Takeya Kasukawa, Janet Kelso, Paul Kersey, Reiko Kikuno, Kouichi Kimura, Bernhard Korn, Vladimir Kuryshev, Izabela Makalowska, Takashi Makino, Shuhei Mano, Regine Mariage-Samson, Jun Mashima, Hideo Matsuda, Hans-Werner Mewes, Shinsei Minoshima, Keiichi Nagai, Hideki Nagasaki, Naoki Nagata, Rajni Nigam, Osamu Ogasawara, Osamu Ohara, Masafumi Ohtsubo, Norihiro Okada, Toshihisa Okido, Satoshi Oota, Motonori Ota, Toshio Ota, Tetsuji Otsuki, Dominique Piatier-Tonneau, Annemarie Poustka, Shuang-Xi Ren, Naruya Saitou, Katsunaga Sakai, Shigetaka Sakamoto, Ryuichi Sakate, Ingo Schupp, Florence Servant, Stephen Sherry, Rie Shiba, Nobuyoshi Shimizu, Mary Shimoyama, Andrew J Simpson, Bento Soares, Charles Steward, Makiko Suwa, Mami Suzuki, Aiko Takahashi, Gen Tamiya, Hiroshi Tanaka, Todd Taylor, Joseph D Terwilliger, Per Unneberg, Vamsi Veeramachaneni, Shinya Watanabe, Laurens Wilming, Norikazu Yasuda, Hyang-Sook Yoo, Marvin Stodolsky, Wojciech Makalowski, Mitiko Go, Kenta Nakai, Toshihisa Takagi, Minoru Kanehisa, Yoshiyuki Sakaki, John Quackenbush, Yasushi Okazaki, Yoshihide Hayashizaki, Winston Hide, Ranajit Chakraborty, Ken Nishikawa, Hideaki Sugawara, Yoshio Tateno, Zhu Chen, Michio Oishi, Peter Tonellato, Rolf Apweiler, Kousaku Okubo, Lukas Wagner, Stefan Wiemann, Robert L Strausberg, Takao Isogai, Charles Auffray, Nobuo Nomura, Takashi Gojobori, Sumio Sugano
Publikováno v: PLoS Biology, Vol 2, Iss 6, p e162 (2004)
The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this area is still limited. Several lines of investigatio
Externí odkaz: https://doaj.org/article/06eb24ad78484cfc8526622555aa94d3
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6
Social communication impairments and restricted, repetitive patterns ('Kodawari') considered from the 'Comprehension' section of the WISC-IV in autism spectrum disorder
Autor: Takahiro Matsuoka, Hiroshi Oda, Toshio Ota, Koji Matsuo, Nobuyuki Shono, Shinji Okinaga, Reiko Sato, Eita Ochi, Yuko Hagiwara, Ayaka Takasugi, Fujio Yokoyama
Publikováno v: Archives of Clinical Psychiatry, Vol 47, Iss 3, Pp 82-84 (2020)
Revista de Psiquiatria Clínica; Vol. 47 Núm. 3 (2020); 82-84
Archives of Clinical Psychiatry; v. 47 n. 3 (2020); 82-84
Archives of Clinical Psychiatry; Vol. 47 No. 3 (2020); 82-84
Archives of Clinical Psychiatry
Universidade de São Paulo (USP)
instacron:USP
Background Many studies have used the Wechsler Intelligence Scale (WISC) to examine the characteristics of autism spectrum disorder (ASD). However, most studies have been based on profile analysis, not on content analysis. Objective The objective of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575e05011e479bee18701b12e76f0fc1
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-60832020000300082&tlng=en
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7
Functional activation of Gαq/11protein via α1‐adrenoceptor in rat cerebral cortical membranes
Autor: Masakazu Kinoshita, Yuji Odagaki, Toshio Ota
Publikováno v: Clinical and Experimental Pharmacology and Physiology. 46:567-574
Although it is recognized that α1 -adrenoceptors are coupled to diverse intracellular signalling pathways, its primary transduction mechanisms are evoked by activating phospholipase C in the cell membrane through Gαq/11 , resulting in production of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd032ab5601f043498a81dbff58a3720
https://doi.org/10.1111/1440-1681.13084
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9
Optimization and pharmacological characterization of receptor‐mediated G i/o activation in postmortem human prefrontal cortex
Autor: Yuji Odagaki, Masakazu Kinoshita, J. Javier Meana, Toshio Ota, Luis F. Callado, Jesús A. García-Sevilla
Publikováno v: Basic & Clinical Pharmacology & Toxicology. 124:649-659
The biochemical abnormalities in transmembrane signal transduction mediated through G protein-coupled receptors (GPCRs) have been postulated as underlying pathophysiology of psychiatric diseases such as schizophrenia and mood disorders. In the presen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4fa122771f70b17909ae1b4bb9088964
https://doi.org/10.1111/bcpt.13183
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10
Dopamine-induced functional activation of Gαq mediated by dopamine D1-like receptor in rat cerebral cortical membranes
Autor: Toshio Ota, Masakazu Kinoshita, Yuji Odagaki
Publikováno v: Journal of Receptors and Signal Transduction. 39:9-17
Although multiple roles of dopamine through D1-like (D1 and D5) and D2-like (D2, D3, and D4) receptors are initiated primarily through stimulation or inhibition of adenylyl cyclase via Gs/olf or Gi/o, respectively, there have been many reports indica
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::decaf9216f6312414d86def99e3e3bd3
https://doi.org/10.1080/10799893.2018.1562470
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