Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Toshio Nakatsuka"'
Publikováno v:
Journal of the Japan Society for Technology of Plasticity. 58:53-59
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7b035ef1bc18ad4d149830c5c17b9c
https://doi.org/10.9773/sosei.58.53
https://doi.org/10.9773/sosei.58.53
Autor:
Masakatsu Yamamoto, Masayuki Kemi, Eri Gondo, Yoshiko Sekiguchi, Akiko Sakaue, Takahiro Sato, Miki Uchida, Toshio Nakatsuka, Yoshiki Ban
Publikováno v:
The Journal of Toxicological Sciences. 30:207-212
Previous studies revealed that atropine reduced male fertility in rats without any effects on mating performance, sperm production and motility, and testicular morphology. The present study was conducted to investigate whether the impairment of male
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5cd8290eee64a538aeb94b855a38614
https://doi.org/10.2131/jts.30.207
https://doi.org/10.2131/jts.30.207
Autor:
Masayuki Kemi, Hiroyoshi Matsumoto, Takahiro Sato, Mark A. Cukierski, Keiji Samura, Toshio Nakatsuka, Yoshiki Ban, Matthew J. Van Zwieten
Publikováno v:
Reproductive Toxicology. 16:757-765
Male rats were treated with a muscarinic receptor antagonist at 3, 10, and 100 mg/kg/day for 4 weeks prior to mating with untreated females and their reproductive status was determined on gestation days (GD) 15–17. Treatment-related decreases in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb0e7a125eacef884e0b8aacf8a4775
https://doi.org/10.1016/s0890-6238(02)00050-3
https://doi.org/10.1016/s0890-6238(02)00050-3
Autor:
Satoru Inagaki, Hiroyoshi Matsumoto, Yoshiki Ban, Toshio Nakatsuka, Minoru Sasaki, Urumi Asanabe
Publikováno v:
The Journal of Toxicological Sciences. 24:407-413
alpha-chlorohydrin (ACH) is a known male reproductive toxicant and produces antifertility in rats. The present experiments were performed to determine the relationship between sperm motions and reproductive function, and to further examine the possib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525e32bf39a85b0875a92b0b115a469e
https://doi.org/10.2131/jts.24.5_407
https://doi.org/10.2131/jts.24.5_407
Publikováno v:
Congenital Anomalies. 37:47-138
The Non-Clinical Evaluation Subcommittee of the Drug Evaluation Committee, Japan Pharmaceutical Manufacturers Association (JPMA) collected historical control data from developmental and reproductive toxicity studies, which were conducted by the membe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb80585ce4df9c09120a5d17e6e21840
https://doi.org/10.1111/j.1741-4520.1997.tb00547.x
https://doi.org/10.1111/j.1741-4520.1997.tb00547.x
Publikováno v:
Journal of Applied Toxicology. 16:147-151
Gestational day 11 rat embryos were cultured for 20 h in the presence of nifedipine (NIF), diltiazem (DIL) and verapamil (VER), and the effects of these calcium channel blockers on embryonic heart rate and gross morphology were examined. Reductions o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7f7589f886ce7096628979ae43fcd7
https://doi.org/10.1002/(sici)1099-1263(199603)16:2<147::aid-jat324>3.0.co
https://doi.org/10.1002/(sici)1099-1263(199603)16:2<147::aid-jat324>3.0.co
Publikováno v:
Toxicological Sciences. 34:141-147
Previous study revealed that calcium channel blockers (CCBs) reduced embryonic heart rates (HRs) and produced morphological abnormalities when Gestational Day (GD) 11.5 rat embryos were cultured for 20 hr. The present study was to investigate whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c447838d7b800d4054accedba9232ef
https://doi.org/10.1093/toxsci/34.1.141
https://doi.org/10.1093/toxsci/34.1.141
Publikováno v:
Archives of Toxicology. 69:65-71
L-691, 121 is a class III antiarrhythmic agent which blocks potassium currents, leading to prolongation of cardiac potential and prevention of cardiac arrhythmia. In a developmental toxicity study in rats, there was a dose-dependent decrease in embry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84cca7494621cc35ce8218a6b54459d5
https://doi.org/10.1007/s002040050139
https://doi.org/10.1007/s002040050139
Publikováno v:
Teratology. 48:139-147
Furosemide produces fetal wavy ribs when administered to pregnant rats during late gestation. The compound is also known to produce metabolic alkalosis in laboratory animals and man. In order to evaluate the effect of furosemide on maternal blood pH,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017a167b2cd672d2143359a92c960abf
https://doi.org/10.1002/tera.1420480208
https://doi.org/10.1002/tera.1420480208
Autor:
Satoru Inagaki, Tetsuro Komatsu, Yoshiki Ban, Hiroyoshi Matsumoto, Masayuki Kemi, Toshio Nakatsuka
Publikováno v:
Experimental animals. 44(4)
The testes of rats were exposed to a single soft x-ray irradiation at levels of 10, 25 and 63 Gy. Testicular and cauda epididymal weights and their sperm counts were decreased at 7 weeks after the irradiation. Histologically, there was an evidence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271b31cd619a15c073c4617e1434b6a3
https://pubmed.ncbi.nlm.nih.gov/8575546
https://pubmed.ncbi.nlm.nih.gov/8575546