Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Toshio Moriya"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Cryogenic electron microscopy (Cryo-EM) is a widely used technique for visualizing the 3D structures of many drug design targets, including membrane proteins, at atomic resolution. However, the necessary throughput for structure-based drug d
Externí odkaz:
https://doaj.org/article/0e42dfba48484d9f930d8fe90cffac3b
Autor:
Makiko Kosugi, Masato Kawasaki, Yutaka Shibata, Kojiro Hara, Shinichi Takaichi, Toshio Moriya, Naruhiko Adachi, Yasuhiro Kamei, Yasuhiro Kashino, Sakae Kudoh, Hiroyuki Koike, Toshiya Senda
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
A light-harvesting chlorophyll-binding protein complex from an Antarctic green alga called Prasiola crispa can excite photosystem II with low energy far-red light. Here, through Cryo-EM analysis, the authors reveal its ring-shaped structure with 11-f
Externí odkaz:
https://doaj.org/article/0336cb8e608642998be266f648b651e5
Autor:
Takuya Miyakawa, Jian Yang, Masato Kawasaki, Naruhiko Adachi, Ayumu Fujii, Yumiko Miyauchi, Tomonari Muramatsu, Toshio Moriya, Toshiya Senda, Masaru Tanokura
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
CphA1 catalyzes the synthesis of cyanophycin polypeptide consisting of equimolar amounts of aspartate and arginine as a fixed nitrogen reservoir in cyanobacteria. Here, the authors solve the cryo-EM structures of CphA1, revealing the aspartate bindin
Externí odkaz:
https://doaj.org/article/c3a6e50e92e54e6a869746a51e5ce283
Autor:
Takahiro Mori, Takuto Kumano, Haibing He, Satomi Watanabe, Miki Senda, Toshio Moriya, Naruhiko Adachi, Sanae Hori, Yuzu Terashita, Masato Kawasaki, Yoshiteru Hashimoto, Takayoshi Awakawa, Toshiya Senda, Ikuro Abe, Michihiko Kobayashi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
In C-glycosides the sugar moiety is linked through a carbon-carbon bond to the non-sugar moiety, which can be cleaved by intestinal microbes. Here, the authors use bioinformatics analysis to identify C-glycoside deglycosidase enzymes in intestinal an
Externí odkaz:
https://doaj.org/article/be2834e7f7604e8f81be75ba24bda5b8
Autor:
Takuo Minato, Takamasa Teramoto, Naruhiko Adachi, Nguyen Khac Hung, Kaho Yamada, Masato Kawasaki, Masato Akutsu, Toshio Moriya, Toshiya Senda, Seiji Ogo, Yoshimitsu Kakuta, Ki-Seok Yoon
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Takuo Minato and colleagues determine the crystal and cryo-EM structures of the native C-phycocyanin (CPC) from the thermophilic cyanobacterium, Thermoleptolyngbya sp. O77, which was found to adopt both a conventional hexameric structure and a novel
Externí odkaz:
https://doaj.org/article/7977b11d91134f86927da4cfa3928abd
Autor:
Yuta Sato, Takashi Yabuki, Naruhiko Adachi, Toshio Moriya, Takatoshi Arakawa, Masato Kawasaki, Chihaya Yamada, Toshiya Senda, Shinya Fushinobu, Takayoshi Wakagi
Publikováno v:
Journal of Structural Biology: X, Vol 4, Iss , Pp 100030- (2020)
Sulfur oxygenase reductases (SORs) are present in thermophilic and mesophilic archaea and bacteria, and catalyze oxygen-dependent oxygenation and disproportionation of elemental sulfur. SOR has a hollow, spherical homo-24-mer structure and reactions
Externí odkaz:
https://doaj.org/article/cf82a56ffee14159a4e70e0e32184580
Autor:
Lassi Paavolainen, Erman Acar, Uygar Tuna, Sari Peltonen, Toshio Moriya, Pan Soonsawad, Varpu Marjomäki, R Holland Cheng, Ulla Ruotsalainen
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e108978 (2014)
Electron tomography (ET) of biological samples is used to study the organization and the structure of the whole cell and subcellular complexes in great detail. However, projections cannot be acquired over full tilt angle range with biological samples
Externí odkaz:
https://doaj.org/article/cf4804fd2e9d45de8910482730e97070
Autor:
Kazuhiko Yamasaki, Naruhiko Adachi, Mya Myat Ngwe Tun, Akihito Ikeda, Toshio Moriya, Masato Kawasaki, Tomoko Yamasaki, Tomomi Kubota, Izuru Nagashima, Hiroki Shimizu, Hiroaki Tateno, Kouichi Morita
Publikováno v:
The FEBS Journal. 290:412-427
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S protein) is highly N-glycosylated, and a "glycan shield" is formed to limit the access of other molecules; however, a small open area coincides with the interface to the ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888dab9bb6c8cac887eb3360f4bc9e16
https://doi.org/10.1111/febs.16599
https://doi.org/10.1111/febs.16599
Autor:
Hui Tao, Lukas Lauterbach, Guangkai Bian, Rong Chen, Anwei Hou, Takahiro Mori, Shu Cheng, Ben Hu, Li Lu, Xin Mu, Min Li, Naruhiko Adachi, Masato Kawasaki, Toshio Moriya, Toshiya Senda, Xinghuan Wang, Zixin Deng, Ikuro Abe, Jeroen S. Dickschat, Tiangang Liu
Publikováno v:
Nature. 606:414-419
All known triterpenes are generated by triterpene synthases (TrTSs) from squalene or oxidosqualene1. This approach is fundamentally different from the biosynthesis of short-chain (C10–C25) terpenes that are formed from polyisoprenyl diphosphates2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f42f3011a5d64b09e7480bcd53619a
https://doi.org/10.1038/s41586-022-04773-3
https://doi.org/10.1038/s41586-022-04773-3
Autor:
Naoya Ohara, Norifumi Kawakami, Ryoichi Arai, Naruhiko Adachi, Toshio Moriya, Masato Kawasaki, Kenji Miyamoto
Publikováno v:
Journal of the American Chemical Society.
Protein nanocages are of increasing interest for use as drug capsules, but the encapsulation and release of drug molecules at appropriate times require the reversible association and dissociation of the nanocages. One promising approach to addressing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7fe640a94ad19dd766e67213c11b736
https://pubmed.ncbi.nlm.nih.gov/36541447
https://pubmed.ncbi.nlm.nih.gov/36541447