Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Toshio Ariga"'
Publikováno v:
ASN Neuro, Vol 15 (2023)
Externí odkaz:
https://doaj.org/article/f80e094adb37429b84398e67e00bdba1
Autor:
Maria Podbielska, Zdzislaw M. Szulc, Toshio Ariga, Anna Pokryszko-Dragan, Wojciech Fortuna, Małgorzata Bilinska, Ryszard Podemski, Ewa Jaskiewicz, Ewa Kurowska, Robert K. Yu, Edward L. Hogan
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 11, Pp 1464-1479 (2020)
Multiple sclerosis (MS) is a CNS disease characterized by immune-mediated demyelination and progressive axonal loss. MS-related CNS damage and its clinical course have two main phases: active and inactive/progressive. Reliable biomarkers are being so
Externí odkaz:
https://doaj.org/article/1a60c2df186d41a794a955403678fd2f
Publikováno v:
ASN Neuro, Vol 8 (2016)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive degeneration of upper and lower motor neurons. Although the etiology of ALS is obscure, genetic studies of familiar ALS suggest a multifactorial etiology
Externí odkaz:
https://doaj.org/article/9fe02c232f644fe28a01c0b072994d0b
Structural analysis of novel bioactive acylated steryl glucosides in pre-germinated brown rice bran1
Autor:
Seigo Usuki, Toshio Ariga, Somsankar Dasgupta, Takeshi Kasama, Keiko Morikawa, Shota Nonaka, Yasuhide Okuhara, Mitsuo Kise, Robert K. Yu
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 10, Pp 2188-2196 (2008)
Previous studies from our laboratory indicated that pre-germinated brown rice (PR) contained certain unknown bioactive lipids that activated two enzymes related to diabetes: Na+/K+ATPase and homocysteine-thiolactonase. In this paper, we report on the
Externí odkaz:
https://doaj.org/article/a0085f8b199b4bc889541040762d7f7d
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 6, Pp 1157-1175 (2008)
Gangliosides are expressed in the outer leaflet of the plasma membrane of the cells of all vertebrates and are particularly abundant in the nervous system. Ganglioside metabolism is closely associated with the pathology of Alzheimer's disease (AD). A
Externí odkaz:
https://doaj.org/article/b24046dcf03640198bac60e67ecb3db9
Autor:
Yu-Teh Li, Eiko Sugiyama, Toshio Ariga, Jun Nakayama, Masayoshi Hayama, Yoichiro Hama, Hiroki Nakagawa, Tadashi Tai, Karol Maskos, Su-Chen Li, Takeshi Ksama
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 7, Pp 1019-1025 (2002)
By TLC, GM4 was found to be the major ganglioside in the liver of six shark species examined: Odontaspis taurus, Negaprion brevirostris, Sphyrna lewini, Mustelus griseus, Mustelus manazo, and Prionace glauca. A detailed analysis of the glycosphingoli
Externí odkaz:
https://doaj.org/article/e72d6d51b8414fa98f74e05554ac9ce4
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 1, Pp 1-16 (1998)
The metazoan nervous system gives rise intradevelopmentally to many more neurons than ultimately survive in the adult. Such excess cells are eliminated through programmed cell death or apoptosis. As is true for cells of other lineages, neuronal survi
Externí odkaz:
https://doaj.org/article/3c4004809fcc48728dd69734ab6f4aa7
Autor:
Toshio Ariga, Yutaka Itokazu, Michael P. McDonald, Yoshio Hirabayashi, Susumu Ando, Robert K. Yu
Publikováno v:
ASN Neuro, Vol 5 (2013)
In order to examine the potential involvement of gangliosides in AD (Alzheimer's disease), we compared the ganglioside compositions of the brains of a double-transgenic (Tg) mouse model [APP (amyloid precursor protein)/PSEN1 (presenilin)] of AD and a
Externí odkaz:
https://doaj.org/article/55246adcfe0146fcb4d5b02123e630ba
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63326 (2013)
The interaction of amyloid β-proteins (Aβ) with membrane gangliosides has been reported to be an early event in Aβ fibril formation in Alzheimer's disease (AD). Neuronal degeneration in AD has been postulated to be associated with the presence of
Externí odkaz:
https://doaj.org/article/7dd037dc6ea7453aa21a6194f2a0cfec
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2011 (2011)
Conversion of the soluble, nontoxic amyloid β-protein (Aβ) into an aggregated, toxic form rich in β-sheets is a key step in the onset of Alzheimer's disease (AD). It has been suggested that Aβ induces changes in neuronal membrane fluidity as a re
Externí odkaz:
https://doaj.org/article/457f2e3560cc44dca603b03e721c1532