Zobrazeno 1 - 10
of 475
pro vyhledávání: '"Toshio, KIMURA"'
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-9 (2020)
Abstract Background Increased levels of cytokines, including interleukin-6 (IL-6), reflect inflammation and have been shown to be predictive of therapeutic responses, fatigue, pain, and depression in patients with rheumatoid arthritis (RA), but limit
Externí odkaz:
https://doaj.org/article/b860e9616b7c45618cb4e77fed50f962
Autor:
Mark C. Genovese, Roy Fleischmann, Alan Kivitz, Eun-Bong Lee, Hubert van Hoogstraten, Toshio Kimura, Gregory St John, Erin K. Mangan, Gerd R. Burmester
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-17 (2020)
Abstract Background The interleukin-6 receptor inhibitor sarilumab demonstrated efficacy in combination with conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) or as monotherapy in patients with moderately to severely active rheu
Externí odkaz:
https://doaj.org/article/12ab6b3c9513426f81af28505c83a39c
Autor:
Cem Gabay, Gerd R. Burmester, Vibeke Strand, Jérôme Msihid, Moshe Zilberstein, Toshio Kimura, Hubert van Hoogstraten, Susan H. Boklage, Jonathan Sadeh, Neil M. H. Graham, Anita Boyapati
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-11 (2020)
Abstract Background Interleukin-6 (IL-6) is a pleiotropic cytokine that plays a key role in the pathogenesis of rheumatoid arthritis. Sarilumab is a human monoclonal antibody that binds membrane-bound and soluble IL-6 receptor-α to inhibit IL-6 sign
Externí odkaz:
https://doaj.org/article/9f7d47705237485b86eba702a5fcce61
Autor:
Papp, Zoltán, Várallyay, Zoltán, Ryuichi Sugizaki, Shigehiro Takasaka, Norihiro Ohishi, Junji Yoshida, Daichi Ogata, Shunya Hayashi, Toshio Kimura
Publikováno v:
Furukawa Electric Review; 2024, Issue 55, p53-56, 4p
Autor:
Vibeke Strand, Laure Gossec, Clare W. J. Proudfoot, Chieh-I Chen, Matthew Reaney, Sophie Guillonneau, Toshio Kimura, Janet van Adelsberg, Yong Lin, Erin K. Mangan, Hubert van Hoogstraten, Gerd R. Burmester
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-12 (2018)
Abstract Background The phase III MONARCH randomized controlled trial (NCT02332590) demonstrated that in patients with rheumatoid arthritis (RA), sarilumab (anti-interleukin-6 receptor monoclonal antibody) monotherapy is superior to adalimumab monoth
Externí odkaz:
https://doaj.org/article/0f4f3986999d4d779a961f01dcdc58ab
Autor:
Toshio, Kimura, Hirokuni, Akahori, Takamasa, Tanaka, Koji, Yanaka, Nagataka, Yoshihara, Kojiro, Miki, Takahiro, Imanaka, Masanori, Asakura, Masaharu, Ishihara
Publikováno v:
Journal of Cardiology. 80:179-183
High lipoprotein (a) [Lp (a)] levels are associated with worse long-term outcomes in patients undergoing percutaneous coronary intervention (PCI). However, there are limited studies investigating association between Lp (a) levels and long-term outcom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0782c42d8e183e6ced161f395b55d5
https://doi.org/10.1016/j.jjcc.2022.03.004
https://doi.org/10.1016/j.jjcc.2022.03.004
Autor:
Koji Yanaka, Hirokuni Akahori, Takahiro Imanaka, Kojiro Miki, Nagataka Yoshihara, Toshio Kimura, Takamasa Tanaka, Masanori Asakura, Masaharu Ishihara
Publikováno v:
Heart and Vessels. 38:171-176
Lipoprotein(a) [Lp(a)] is a risk factor for peripheral artery disease (PAD). However, the relationship between Lp(a) levels and clinical events after endovascular therapy (EVT) for the femoropopliteal artery in PAD patients remains unclear. Thus, thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83059de4d9a77c2ba48700a3c255fb77
https://doi.org/10.1007/s00380-022-02151-7
https://doi.org/10.1007/s00380-022-02151-7
Autor:
Shigehiro Takasaka, Norihiro Ohishi, Satoru Ichihara, Nitidet Thudsalingkarnsakul, Naoya Hojo, Yasuto Tatamida, Junji Yoshida, Sanguan Anantathanasarn, Toshio Kimura
Publikováno v:
2023 Optical Fiber Communications Conference and Exhibition (OFC).
We measure characteristics of a transmitted WDM signal in an 80 km-long SMF under bi-directionally pumped DRA with incoherent-forward and coherent-backward pumps. The signal shows OSNR of 50.0 dB and RIN less than -140 dB/Hz.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::082bae261d2093d019c27bacfecd5b28
https://doi.org/10.23919/ofc49934.2023.10116118
https://doi.org/10.23919/ofc49934.2023.10116118
Publikováno v:
Optical Fiber Communication Conference (OFC) 2023.
Highly nonlinear fibers which can be utilized in all-optical signal processing is introduced. Characteristics of highly nonlinear fiber and requirements from various applications are summarized.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de152826def10c971d29e6a90a462d5d
https://doi.org/10.1364/ofc.2023.th1b.1
https://doi.org/10.1364/ofc.2023.th1b.1
Autor:
Takahiro Imanaka, Nagataka Yoshihara, Masanori Asakura, Kojiro Miki, Toshio Kimura, Koji Yanaka, Hirokuni Akahori, Takamasa Tanaka, Masaharu Ishihara
Publikováno v:
Journal of Atherosclerosis and Thrombosis
Aim: High levels of lipoprotein(a) [Lp(a)] are a risk factor for peripheral artery disease (PAD). However, the relationship between Lp(a) levels and the severity of femoropopliteal lesions in patients with PAD has not been systematically studied. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076ba06e801fa297217f6754f7713cdf
https://doi.org/10.5551/jat.56457
https://doi.org/10.5551/jat.56457