Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Toshinori Totsugawa"'
Autor:
Taichi Sakaguchi, Nobuyuki Kagiyama, Misako Toki, Arudo Hiraoka, Akihiro Hayashida, Toshinori Totsugawa, Kentaro Tamura, Genta Chikazawa, Hidenori Yoshitaka, Kiyoshi Yoshida
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 11 (2018)
BackgroundCarpentier's techniques for degenerative posterior mitral leaflet prolapse have been established with excellent long‐term results reported. However, residual mitral regurgitation (MR) occasionally occurs even after a straightforward repai
Externí odkaz:
https://doaj.org/article/7b5634c7be5e42fd830425d07cf2e0ed
Autor:
Masanobu Maruyama, Toshinori Totsugawa, Takemi Kunieda, Teru Okitsu, Norikuni Shibata, Michihiko Takesue, Yuzuru Kurabayashi, Mizuko Oshita, Shuhei Nakaji, Makoto Kodama, Noriaki Tanaka, Naoya Kobayashi M.D., PH.D
Publikováno v:
Cell Transplantation, Vol 12 (2003)
Externí odkaz:
https://doaj.org/article/d6dc3254b7314265a1c9c792a89e1e07
Autor:
Takemi Kunieda, Masanobu Maruyama, Teru Okitsu, Norikuni Shibata, Michihiko Takesue, Toshinori Totsugawa, Yoshikazu Kosaka, Takashi Arata, Kazuya Kobayashi, Hideaki Ikeda, Mizuko Oshita, Shuhei Nakaji, Kenji Ohmoto, Shinichiro Yamamoto, Yuzuru Kurabayashi, Makoto Kodama, Noriaki Tanaka, Naoya Kobayashi M.D., PH.D.
Publikováno v:
Cell Transplantation, Vol 12 (2003)
Development of liver-targeted cell therapies, such as hepatocyte transplantation and bioartificial livers, requires a large amount of functional hepatocytes as needed. To achieve this development, establishing an excellent cryopreservation method of
Externí odkaz:
https://doaj.org/article/b7d12d6e7db5427284cc48a2a0f8fddf
Autor:
Michihiko Takesue, Masanobu Maruyama, Norikuni Shibata, Takemi Kunieda, Teru Okitsu, Masakiyo Sakaguchi, Toshinori Totsugawa, Yoshikazu Kosaka, Akira Arata, Hideaki Ikeda, Junji Matsuoka, Toshie Oyama, Makoto Kodama, Kenji Ohmoto, Shinichiro Yamamoto, Yuzuru Kurabayashi, Itaru Yamamoto, Noriaki Tanaka, Naoya Kobayashi M.D., PH.D.
Publikováno v:
Cell Transplantation, Vol 12 (2003)
Normal human hepatocytes are an ideal source of liver-targeted cell therapies, such as hepatocyte transplantation and bioartificial livers, but availability of human donor livers for liver cell isolation is severely limited. To effectively utilize sc
Externí odkaz:
https://doaj.org/article/c470f3641f9b4be9b745291f583c16bb
Autor:
Takemi Kunieda, Naoya Kobayashi M.D., Ph.D., Masakiyo Sakaguchi, Teru Okitsu, Toshinori Totsugawa, Takamasa Watanabe, Toshihisa Matsumura, Masanobu Maruyama, Hirofumi Noguchi, Michihiko Takesue, Norikuni Shibata, Kenji Ohmoto, Toshiyoshi Fujiwara, Shinichiro Yamamoto, Noriaki Tanaka
Publikováno v:
Cell Transplantation, Vol 11 (2002)
We previously constructed an immortal human hepatocyte line NKNT-3 with a simian virus 40 T antigen (SV40T) to develop cell-based biological therapies. p21 is a molecule that regulates the transition from the G 1 phase to the S phase of the cell cycl
Externí odkaz:
https://doaj.org/article/c909ab7ded8b494189105a8eda773793
Autor:
Toshinori Totsugawa, Naoya Kobayashi M.D., Teru Okitsu, Hirofumi Noguchi, Takamasa Watanabe, Toshihisa Matsumura, Masanobu Maruyama, Toshiyoshi Fujiwara, Masakiyo Sakaguchi, Noriaki Tanaka
Publikováno v:
Cell Transplantation, Vol 11 (2002)
Because one of the attractive characteristics of human immunodeficiency virus type 1 (HIV-1)-based lentiviral vectors is that it can infect even nondividing cells, a lentivirus-mediated gene delivery system is currently being paid a great deal of att
Externí odkaz:
https://doaj.org/article/05ecea8d19a44fe198870dcccf987926
Autor:
Naoya Kobayashi M.D., Ph.D., Hirofumi Noguchi, Toshinori Totsugawa, Takamasa Watanabe, Toshihisa Matsumura, Toshiyoshi Fujiwara, Masahiro Miyazaki, Kenichi Fukaya, Masayoshi Namba, Noriaki Tanaka
Publikováno v:
Cell Transplantation, Vol 10 (2001)
For developing a bioartificial liver (BAL) device, an attractive alternative to the primary human hepatocytes would be the use of highly differentiated immortalized human hepatocytes with a safeguard. To test the feasibility, the primary human hepato
Externí odkaz:
https://doaj.org/article/b517b4c4975744b28a3328f3b143c558
Autor:
Naoya Kobayashi M.D., Ph.D., Hirofumi Noguchi, Karen A. Westerman, Takamasa Watanabe, Toshihisa Matsumura, Toshinori Totsugawa, Toshiyoshi Fujiwara, Philippe Leboulch, Noriaki Tanaka
Publikováno v:
Cell Transplantation, Vol 10 (2001)
Current clinical reports have indicated that hepatocyte transplantation (HTX) could be used in patients with liver failure and in children with liver-based metabolic diseases. One of the major limiting factors of HTX is a serious shortage of donor li
Externí odkaz:
https://doaj.org/article/5816b304085146d58b581d526a51a30c
Autor:
Naoya Kobayashi M.D., Ph.D., Hirofumi Noguchi, Karen A. Westerman, Takamasa Watanabe, Toshihisa Matsumura, Toshinori Totsugawa, Toshiyoshi Fujiwara, Philippe Leboulch, Noriaki Tanaka
Publikováno v:
Cell Transplantation, Vol 10 (2001)
An ideal alternative to the primary human hepatocytes for hepatocyte transplantation would be to use a clonal cell line that grows economically in culture and exhibits the characteristics of differentiated, nontransformed hepatocytes following transp
Externí odkaz:
https://doaj.org/article/600036b49e2d4b8d9528c2218746c5d6
Autor:
Naoya Kobayashi M.D., Ph.D., Takehito Taguchi, Hirofumi Noguchi, Teru Okitsu, Toshinori Totsugawa, Takamasa Watanabe, Toshihisa Matsumura, Toshiyoshi Fujiwara, Haruo Urata, Nobuyuki Kishimoto, Nobuyuki Hayashi, Shuhei Nakaji, Takuro Murakami, Noriaki Tanaka
Publikováno v:
Cell Transplantation, Vol 10 (2001)
With the development of biotechnology, hepatic support by a hybrid artificial liver (HAL) using hepatocytes has been given much attention. Because the availability of human livers is limited, we have established a tightly regulated immortal human hep
Externí odkaz:
https://doaj.org/article/79a267fc4c2f4b00a9385f80789265f7