Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Toshinori Ishizuya"'
Autor:
Aya Takakura, Takanori Sato, Ji-Won Lee, Kyoko Hirano, Ryoko Takao-Kawabata, Toshinori Ishizuya, Tadahiro Iimura
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-19 (2022)
Abstract Osteoporosis is an age-related disorder that is characterized by reduced bone mass. Its prevention and treatment are important healthcare issues for maintaining social activity in aged societies. Although bone fractures mostly occur at sites
Externí odkaz:
https://doaj.org/article/26a36f230a114b65a2247292a81b70cf
Autor:
Kenji Ogura, Tadahiro Iimura, Yuji Makino, Ayano Sugie-Oya, Aya Takakura, Ryoko Takao-Kawabata, Toshinori Ishizuya, Keiji Moriyama, Akira Yamaguchi
Publikováno v:
Bone Reports, Vol 5, Iss , Pp 7-14 (2016)
Intermittent administration of human parathyroid hormone (1–34)[hPTH(1–34)] induces anabolic action on the bones. To understand the mechanism underlying the early phase of hPTH(1–34)-induced anabolic action, we investigated the expression profi
Externí odkaz:
https://doaj.org/article/f522fc1b65174ec281003707d8a5e387
Autor:
Hiroshi Yamane, Aya Takakura, Yukari Shimadzu, Toshiyuki Kodama, Ji-Won Lee, Yukihiro Isogai, Toshinori Ishizuya, Ryoko Takao-Kawabata, Tadahiro Iimura
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175329 (2017)
Teriparatide [human parathyroid hormone (1-34)], which exerts an anabolic effect on bone, is used for the treatment of osteoporosis in patients who are at a high risk for fracture. That the once-daily administration of teriparatide causes an increase
Externí odkaz:
https://doaj.org/article/ce76b8f576634e3ba4a9e32f3a880dd1
Autor:
Aya Takakura, Takanori Sato, Ji-Won Lee, Kyoko Hirano, Ryoko Takao-Kawabata, Toshinori Ishizuya, Tadahiro Iimura
Osteoporosis is an age-related disorder that is characterized by reduced bone mass. Its prevention and treatment are important healthcare issues for maintaining social activity in aged societies. Although bone fractures mostly occur at sites of weake
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7176e59f8ac3f327e636285b580767c1
https://doi.org/10.21203/rs.3.rs-1711132/v1
https://doi.org/10.21203/rs.3.rs-1711132/v1
Autor:
Yasuhiro Kobayashi, Koichi Matsuo, Naoyuki Takahashi, Toru Hiraga, Ryoko Takao-Kawabata, Nobuyuki Udagawa, Atsushi Arai, Akira Yamaguchi, Toshinori Ishizuya, Toshihisa Komori, Mengyu Yang, Yukihiro Isogai, Kohei Murakami, Toshihide Mizoguchi, Lijuan Zhao, Daisuke Nishida
Publikováno v:
Journal of Bone and Mineral Research. 34:1952-1963
Intermittent parathyroid hormone (iPTH) treatment induces bone anabolic effects that result in the recovery of osteoporotic bone loss. Human PTH is usually given to osteoporotic patients because it induces osteoblastogenesis. However, the mechanism b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c88d382fe9c926bba74f0b5130e6a10
https://doi.org/10.1002/jbmr.3811
https://doi.org/10.1002/jbmr.3811
Autor:
I. Kudo, Aya Takakura, M. Nakatsugawa, T. Kobayashi, Ryoko Takao-Kawabata, T. Tanaka, T. Shimizu, Toshinori Ishizuya
Publikováno v:
Bone Reports
Bone Reports, Vol 7, Iss C, Pp 70-82 (2017)
Bone Reports, Vol 7, Iss C, Pp 70-82 (2017)
Bisphosphonates (BPs) and teriparatide (TPTD) are both effective treatments for osteoporosis, but BP treatment prior to daily TPTD treatment has been shown to impair the effect of TPTD in some clinical studies. In contrast, the loss of bone mineral d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2d8633c55df6fdd9e265599d803e73
http://europepmc.org/articles/PMC5602747
http://europepmc.org/articles/PMC5602747
Autor:
Momoko Nakatsugawa, Hirotoshi Utsunomiya, Akihiko Tokuda, Aya Takakura, Yukihiro Isogai, Misa Nakamura, Ryoko Takao-Kawabata, Ryohei Kono, Akihiro Maeno, Toshinori Ishizuya, Akihiro Kitami, Sachiko Nomura
Publikováno v:
Endocrinology
Osteoporosis is a complication of diabetes mellitus (DM). The pathology of diabetic osteoporosis is distinct from postmenopausal osteoporosis, and there are no specific treatment guidelines for diabetic osteoporosis. In the current study, this issue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a444f6905bd61ded2aa2205ed79c61
https://pubmed.ncbi.nlm.nih.gov/31504411
https://pubmed.ncbi.nlm.nih.gov/31504411
Autor:
Hiroshi Kuriyama, Emika Sugimoto, Yukihiro Isogai, Toshinori Ishizuya, Aya Takakura, Ryoko Takao-Kawabata, Ichiro Ikegaki, Osamu Nakazono
Publikováno v:
Calcified Tissue International
Intermittent repeated administration of teriparatide (TPTD) has potent anabolic effects on bones in vivo. However, TPTD has both anabolic and catabolic effects on osteoblasts in vitro, and the mechanisms underlying its promotion of bone formation are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf4f086833b971a74f31459722bee97
https://doi.org/10.1007/s00223-015-0026-1
https://doi.org/10.1007/s00223-015-0026-1
Autor:
Ryoko Takao-Kawabata, Ayano Sugie-Oya, Toshinori Ishizuya, Aya Takakura, Yukihiro Isogai, Yukari Shimazu, Hiroko Sano, Akira Yamaguchi
Publikováno v:
Journal of Bone and Mineral Metabolism. 34:303-314
Teriparatide and bisphosphonates are osteoporosis medications that increase bone mineral density (BMD) and prevent fracture, but each has a different mechanism of action. Teriparatide promotes bone formation, while bisphosphonates suppress bone resor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7623c2cd7007a86e12fb5bb84b8143
https://doi.org/10.1007/s00774-015-0670-6
https://doi.org/10.1007/s00774-015-0670-6
Autor:
Makoto Kajiwara, Aya Takakura, Ryoko Takao-Kawabata, Sadakazu Ejiri, Hisashi Murayama, Yukihiro Isogai, Toshinori Ishizuya
Publikováno v:
Journal of Bone and Mineral Metabolism. 34:291-302
Bone histomorphometry is usually performed on the iliac bone in humans and the tibia or vertebrae in rats. Bone metabolism differences among skeletal sites may be problematic when translating experimental results from rats to humans, but data on such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::235d48619d62fc8549f2bd4cc2149449
https://doi.org/10.1007/s00774-015-0678-y
https://doi.org/10.1007/s00774-015-0678-y