Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Toshinobu Nakamura"'
Autor:
Keisuke Toriyama, Wan Kin Au Yeung, Azusa Inoue, Kazuki Kurimoto, Yukihiro Yabuta, Mitinori Saitou, Toshinobu Nakamura, Toru Nakano, Hiroyuki Sasaki
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Genome-wide DNA demethylation occurs in mammalian primordial germ cells (PGCs) as part of the epigenetic reprogramming important for gametogenesis and resetting the epigenetic information for totipotency. Dppa3 (also known as Stel
Externí odkaz:
https://doaj.org/article/00e65864e7a743a1982400d04bcbce0c
Autor:
Yoichi Sekita, Yuki Sugiura, Akari Matsumoto, Yuki Kawasaki, Kazuya Akasaka, Ryo Konno, Momoka Shimizu, Toshiaki Ito, Eiji Sugiyama, Terushi Yamazaki, Eriko Kanai, Toshinobu Nakamura, Makoto Suematsu, Fumitoshi Ishino, Yoshio Kodera, Takashi Kohda, Tohru Kimura
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-15 (2021)
Abstract Background Phosphoinositide-3 kinase (PI3K)/AKT signaling participates in cellular proliferation, survival and tumorigenesis. The activation of AKT signaling promotes the cellular reprogramming including generation of induced pluripotent ste
Externí odkaz:
https://doaj.org/article/305914cc50854a9697a903f692dbfafd
Autor:
Xiaobo Yin, Shota Yamada, Hiroaki Kobayashi, Ryota Tanaka, Yuki Togo, Miho Hosoi, Mie Tsuchida, Tatsuki Kunoh, Shuichi Wada, Toshinobu Nakamura, Ryuzo Sasaki, Tamio Mizukami, Makoto Hasegawa
Publikováno v:
FEBS Open Bio, Vol 11, Iss 8, Pp 2110-2117 (2021)
Overexpression of human dynactin‐associated protein isoform a (dynAPa) transforms NIH3T3 cells. DynAPa is a single‐pass transmembrane protein with a carboxy‐terminal region exposed to the outside of cells. According to the NCBI RefSeq database,
Externí odkaz:
https://doaj.org/article/215a5b3280c54c8094d6e7033e48be49
Autor:
Daiki Haraguchi, Toshinobu Nakamura
Publikováno v:
Biochemistry and Biophysics Reports, Vol 30, Iss , Pp 101267- (2022)
Somatic cells can be reprogrammed into induced pluripotent stem (iPS) cells by forced expression of the transcription factors Oct3/4, Klf4, Sox2, and c-Myc (OKSM). Somatic cell nuclear transfer can also be utilized to reprogram somatic cells into tot
Externí odkaz:
https://doaj.org/article/d06af630ee79469e9983f5db429a8784
Autor:
Asuka FURUTA, Toshinobu NAKAMURA
Publikováno v:
The Journal of Reproduction and Development, Vol 67, Iss 2, Pp 79-81 (2021)
Embryonic stem (ES) cells, derived from the inner cell mass of a blastocyst, are believed to pluripotent cells and give rise to embryonic, but not extraembryonic, tissues. In mice, totipotent 2-cell stage embryo-like (2-cell-like) cells, which are id
Externí odkaz:
https://doaj.org/article/fb9913a53e524cecaa6c4f5b6eee3cb4
Autor:
Yuki Hatanaka, Takeshi Tsusaka, Natsumi Shimizu, Kohtaro Morita, Takehiro Suzuki, Shinichi Machida, Manabu Satoh, Arata Honda, Michiko Hirose, Satoshi Kamimura, Narumi Ogonuki, Toshinobu Nakamura, Kimiko Inoue, Yoshihiko Hosoi, Naoshi Dohmae, Toru Nakano, Hitoshi Kurumizaka, Kazuya Matsumoto, Yoichi Shinkai, Atsuo Ogura
Publikováno v:
Cell Reports, Vol 20, Iss 12, Pp 2756-2765 (2017)
At fertilization, the paternal genome undergoes extensive reprogramming through protamine-histone exchange and active DNA demethylation, but only a few maternal factors have been defined in these processes. We identified maternal Mettl23 as a protein
Externí odkaz:
https://doaj.org/article/1499703dd6374e0eae25b8331e82bcfd
Autor:
Satoshi Nakamura, Tomoko Yamada, Naoka Umemoto, Toshinobu Nakamura, Koji Wakatabi, Eri Iida, Masumi Masaki, Maki Kakurai, Toshio Demitsu
Publikováno v:
Case Reports in Dermatology, Vol 7, Iss 1, Pp 56-60 (2015)
We present clinically peculiar facial discoid lupus erythematosus (DLE) that mimicked tinea faciei. Although DLE is a chronic autoimmune dermatosis, it has a variety of rare clinical presentations, including periorbital DLE, comedonic DLE and hypertr
Externí odkaz:
https://doaj.org/article/a30196ae16524526befb64db251df545
Publikováno v:
Nutrition and Metabolic Insights, Vol 10 (2017)
We investigated the effects of vitamin B 1 deficiency on the meiosis maturation of oocytes. Female Crl:CD1 (ICR) mice were fed a 20% casein diet (control group) or a vitamin B 1 –free diet (test group). The vitamin B 1 concentration in ovary was ap
Externí odkaz:
https://doaj.org/article/1540b10ced34489d874ba5557da45bd3
Autor:
Tatsuki Kunoh, Weixiang Wang, Hiroaki Kobayashi, Daisuke Matsuzaki, Yuki Togo, Masahiro Tokuyama, Miho Hosoi, Koichi Koseki, Shu-Ichi Wada, Nobuo Nagai, Toshinobu Nakamura, Shintaro Nomura, Makoto Hasegawa, Ryuzo Sasaki, Tamio Mizukami
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135836 (2015)
Human dynactin-associated protein (dynAP) is a transmembrane protein that promotes AktSer473 phosphorylation. Here, we report the oncogenic properties of dynAP. In contrast to control NIH3T3 cells expressing LacZ (NIH3T3LacZ), NIH3T3dynAP cells vigor
Externí odkaz:
https://doaj.org/article/0ccf4a4d32ed447a9990bf8f709a722c
Autor:
Tohru Kimura, Fumitoshi Ishino, Eriko Kanai, Toshinobu Nakamura, Makoto Suematsu, Yoichi Sekita, Toshiaki Ito, Kazuya Akasaka, Terushi Yamazaki, Akari Matsumoto, Yuki Kawasaki, Takashi Kohda, Yoshio Kodera, Momoka Shimizu, Ryo Konno, Yuki Sugiura, Eiji Sugiyama
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-15 (2021)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
BackgroundPhosphoinositide-3 kinase (PI3K)/AKT signaling participates in cellular proliferation, survival and tumorigenesis. The activation of AKT signaling promotes the cellular reprogramming including generation of induced pluripotent stem cells (i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fae9652ec5e367ff60ae28d7fc1a3ee
https://doaj.org/article/305914cc50854a9697a903f692dbfafd
https://doaj.org/article/305914cc50854a9697a903f692dbfafd