Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Toshinobu Aoyama"'
Autor:
Yumiko Hironaga, Youichi Hachitanda, Keiichi Ikeda, Tetsuya Mitsuishi, Toshinobu Aoyama, Kenji Otubo, Kohji Sue, Akira Nakagawara
Publikováno v:
Medical and Pediatric Oncology. 17:496-500
Two cases with unresectable hepatoblastoma were treated by intrahepatic arterial injections of cisplatin-phosphatidylcholine-Lipiodol suspension (CPLS), combined with systemic chemotherapy. Unfortunately, the first patient who was given three injecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7169c5a2834a62c8737c8f158e98a7c0
https://doi.org/10.1002/mpo.2950170528
https://doi.org/10.1002/mpo.2950170528
Autor:
Yoshinobu Goto, Miho Yukawa, Toshinobu Aoyama, Eiji Yukawa, Shun Higuchi, Shigehiro Ohdo, Masao Minemoto, Fumihiro Suematu
Publikováno v:
Clinical Pharmacokinetics. 40:773-781
To clarify the observed variability of digoxin disposition by performing a population pharmacokinetic analysis in a Japanese population.Retrospective analysis of clinical pharmacokinetic data.Data were obtained from 106 patients with heart failure an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc7e55e7390cc7f83096afe523444d8c
https://doi.org/10.2165/00003088-200140100-00005
https://doi.org/10.2165/00003088-200140100-00005
Autor:
Tsuyoshi Hokazono, Masayasu Satou, Toshinobu Aoyama, Shigehiro Ohdo, Eiji Yukawa, Shun Higuchi
Publikováno v:
American Journal of Therapeutics. 7:303-308
With antiepileptic drugs, the marked inter- and intrapatient variability of the concentration-dose ratio makes it difficult to predict serum concentrations from the dose administered per kilogram. The effects of comedication on steady-state serum con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f0f587d07f2bb06f2a2bebe49729a7e
https://doi.org/10.1097/00045391-200007050-00006
https://doi.org/10.1097/00045391-200007050-00006
Publikováno v:
European Journal of Clinical Pharmacology. 54:69-74
Objective: Nonlinear mixed-effects modeling (NONMEM) was used to estimate the effects of drug–drug interaction on phenobarbitone clearance values, using 648 serum levels gathered during the routine clinical care of 349 pediatric and adult epileptic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ed84acdd89929243ddcd96d37ad034
https://doi.org/10.1007/s002280050423
https://doi.org/10.1007/s002280050423
Publikováno v:
The Journal of Clinical Pharmacology. 37:1160-1167
Nonlinear mixed effects modeling (NONMEM) was used to estimate the effects of drug-drug interaction on valproic acid relative clearance values using 792 serum levels gathered from 400 pediatric and adult patients with epilepsy (age range, 0.3-54.8 ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e13c180f04eb628769a2755844bb76
https://doi.org/10.1002/j.1552-4604.1997.tb04301.x
https://doi.org/10.1002/j.1552-4604.1997.tb04301.x
Publikováno v:
The Journal of Clinical Pharmacology. 37:92-100
The steady-state concentrations of digoxin at trough levels were studied to reestablish the role of patient characteristics in estimating doses for digoxin using routine therapeutic drug-monitoring data. The data (n = 548) showing steady-state serum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e950017a19ff703c8cd141dc3b7d19
https://doi.org/10.1002/j.1552-4604.1997.tb04766.x
https://doi.org/10.1002/j.1552-4604.1997.tb04766.x
Autor:
Toshinobu Aoyama, Eiji Yukawa
Publikováno v:
The Journal of Clinical Pharmacology. 36:752-759
Multiple peak approach screening was used to detect the effects of other antiepileptic drugs on the population estimates of relative clearance of carbamazepine. Routine clinical pharmacokinetic data (N = 1,010) collected from 466 patients receiving c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5297043a5dc8fe4d1dc1b6b4d8e63bcc
https://doi.org/10.1002/j.1552-4604.1996.tb04246.x
https://doi.org/10.1002/j.1552-4604.1996.tb04246.x
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics. 21:9-13
Filter occlusion during intravenous infusion of injectable menatetrenone in an electrolyte fluid was examined. The menatetrenone concentration and its emulsion droplet size were not changed by in-line filtration. However, particle counts in the admix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31745a9bcf661816c837f429880579da
https://doi.org/10.1046/j.1365-2710.1996.88875888.x
https://doi.org/10.1046/j.1365-2710.1996.88875888.x
Publikováno v:
Japanese Journal of Hospital Pharmacy. 21:56-62
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2839b371408c0c73d21b649dcd30857
https://doi.org/10.5649/jjphcs1975.21.56
https://doi.org/10.5649/jjphcs1975.21.56
Publikováno v:
Biological and Pharmaceutical Bulletin. 18:1793-1796
The quality of three commercial injections (Genotropin, Humatrope and Norditropin) of lyophilized recombinant human growth hormone (r-hGH) was evaluated in tests by visual inspection, high-performance gel permeation chromatography, polyacrylamide gel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77cf8aa0e39fe0846d046707e6fab5ce
https://doi.org/10.1248/bpb.18.1793
https://doi.org/10.1248/bpb.18.1793