Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Toshimitsu Kishimoto"'
Autor:
Yayoi Yoshimura, Toshimitsu Kishimoto, Hiroki Shimizu, Yasunori Chiba, Izuru Nagashima, Takayuki Yokoe
Publikováno v:
Carbohydrate research. 492
Glycopeptides are fragments of glycoproteins and are important in evaluating the biological roles of carbohydrates in glycoproteins. Fmoc solid-phase peptide synthesis using acetyl-protected glycosylated amino acids is a common strategy for the prepa
Autor:
Toshimitsu Kishimoto, Tatsuro Irimura, Hiroki Shimizu, Yayoi Yoshimura, Shigeyuki Shichino, Kaori Denda-Nagai, Yoshie Takahashi, Izuru Nagashima, Yasunori Chiba, Miki Noji
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Anti-mucin1 (MUC1) antibodies have long been used clinically in cancer diagnosis and therapy and specific bindings of some of them are known to be dependent on the differential glycosylation of MUC1. However, a systematic comparison of the binding sp
Autor:
Yuko Ono, Yuuichi Ono, Yasushi Horai, Toshimitsu Kishimoto, Hiroyuki Utsumi, Atsushi Fukunari
Publikováno v:
International journal of experimental pathology. 97(1)
Summary SHRSP5/Dmcr is a newly established substrain of stroke-prone spontaneously hypertensive rat (SHRSP). Recently, high-fat and high-cholesterol (HFC) diet-fed SHRSP5/Dmcr has been reported as a novel rat model of developing hepatic lesions simil
Publikováno v:
European Journal of Neuroscience. 17:2231-2235
The objective of the present study was to investigate the potential role of corticotropin-releasing factor receptor subtype 2 (CRFR2) in autonomic regulation of heart rate and heart rate variability under physiological conditions in conscious mice. H
Autor:
Helen C. Christian, Holly A. Thomas, Edward T. Wei, Toshimitsu Kishimoto, Julia C. Buckingham
Publikováno v:
Peptides. 19:1183-1190
The activities of corticotropin-releasing hormone (CRH)-related peptides and several analogs were examined in cells transfected with either CRH1 or CRH2β receptors, in suppression of heat-induced rat paw edema in pentobarbital-anesthetised animals a
Autor:
Toshimitsu Kishimoto, Kunji Kawai, Yoshihiro Fuchigami, Wakako Watanabe, Hideo Kubodera, Takahide Kaji, Sawako Yoshida
Publikováno v:
Biochemical and biophysical research communications. 395(2)
Apoptosis signal-regulating kinase 1 (ASK1) and ASK2 are both members of mitogen-activated protein kinase kinase kinase (MAP3K) family that are implicated in apoptotic cell death, stress responses, and various diseases. We have determined that NT2RI3
Publikováno v:
The European journal of neuroscience. 17(10)
The objective of the present study was to investigate the potential role of corticotropin-releasing factor receptor subtype 2 (CRFR2) in autonomic regulation of heart rate and heart rate variability under physiological conditions in conscious mice. H
Autor:
Michael G. Rosenfeld, Toshimitsu Kishimoto, Ola Hermanson, Jelena Radulovic, Marko Radulovic, Farideh Hooshmand, Joachim Spiess, Christina Schrick, Chijen R. Lin
Publikováno v:
Karolinska Institutet
Corticotropin-releasing hormone (Crh), a 41-residue polypeptide, activates two G-protein-coupled receptors, Crhr1 and Crhr2, causing (among other transductional events) phosphorylation of the transcription factor Creb. The physiologic role of these r
Autor:
Elvira Lopez-Perez, Toshimitsu Kishimoto, Sergio Iavicoli, Gertrude C. Buehring, Edward T. Wei, Holly A. Thomas
Publikováno v:
European journal of pharmacology. 349(2-3)
Human neutrophils in whole blood become bipolar in shape after exposure to chemokinetic stimuli. In normal blood, the proportion of non-spherical neutrophils was 1.2 +/- 0.07% (n = 101). After incubation of blood samples with corticotropin-releasing
Publikováno v:
European journal of pharmacology. 306(1-3)
Corticotropin-releasing factor (CRF) acts on at least two types of CRF receptors. To search for selective CRF receptor agonists, 37 ovine CRF analogs, systematically substituted with d -amino acids, were tested for inhibitory activity on edema induce