Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Toshimitsu Kajiwara"'
Autor:
Yasuaki Tamura, Yoshiharu Okamoto, Koichi Hirata, Toshimitsu Kajiwara, Noriyuki Sato, Yoshihiko Hirohashi, Toshihiko Torigoe, Tsutomu Tanaka, Vitaly Kochin, Takayuki Kanaseki, Goro Kutomi, Tomohide Tsukahara, Kazuharu Kukita
Publikováno v:
Oncotarget
// Tsutomu Tanaka 1, 2 , Goro Kutomi 3 , Toshimitsu Kajiwara 1 , Kazuharu Kukita 3 , Vitaly Kochin 1 , Takayuki Kanaseki 1 , Tomohide Tsukahara 1 , Yoshihiko Hirohashi 1 , Toshihiko Torigoe 1 , Yoshiharu Okamoto 4 , Koichi Hirata 3 , Noriyuki Sato 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5590dd05323ad1c08b5ab5b96ad85aa6
https://doi.org/10.18632/oncotarget.14960
https://doi.org/10.18632/oncotarget.14960
Autor:
Takehiro Kurotaki, Toshihiko Torigoe, Tomohide Tsukahara, Keita Saito, Yoshiharu Okamoto, Koichi Hirata, Yoshihiko Hirohashi, Noriyuki Sato, Goro Kutomi, Takayuki Kanaseki, Tsutomu Tanaka, Toshimitsu Kajiwara, Yasuaki Tamura
Publikováno v:
Immunology Letters. 167:34-40
Plasmacytoid dendritic cells (pDCs) are the main producers of IFN-α in response to unmethylated DNA molecules, including cytosine guanine dinucleotide (CpG)-DNA in vivo. pDCs specifically express toll-like receptor (TLR) 9 and are therefore able to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad8d052abda296b6223c6b1ad5977b7
https://doi.org/10.1016/j.imlet.2015.06.014
https://doi.org/10.1016/j.imlet.2015.06.014
Autor:
Yasuaki Tamura, Yoshiharu Okamoto, Noriyuki Sato, Tsutomu Tanaka, Toshihiko Torigoe, Toshimitsu Kajiwara
Publikováno v:
The Journal of Immunology. 194:2004-2010
Endoplasmic reticulum disulfide oxidase ERO1-α plays a role in the formation of disulfide bonds in collaboration with protein disulfide isomerase. Disulfide bond formation is required for the proper conformation and function of secreted and cell sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7c152d510d86d0af4bd526ea0a074b
https://doi.org/10.4049/jimmunol.1402538
https://doi.org/10.4049/jimmunol.1402538
Autor:
Yoshiharu Okamoto, Koichi Hirata, Koichi Okuya, Toshihiko Torigoe, Yoshihiko Hirohashi, Goro Kutomi, Yasuaki Tamura, Noriyuki Sato, Toshimitsu Kajiwara, Takayuki Kanaseki, Tomohide Tsukahara, Akari Takaya, Tsutomu Tanaka
Publikováno v:
Cancer Science
The presentation of an exogenous antigen in a major histocompatibility complex class-I- restricted fashion to CD8(+) T cells is called cross-presentation. Heat shock proteins (HSPs) such as Hsp70, gp96, and Hsp90 have been shown to elicit efficient C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5c9a3873a7323d2fbb15dca43b4427
https://doi.org/10.1111/cas.12570
https://doi.org/10.1111/cas.12570
Autor:
Toshimitsu, Kajiwara, Tsutomu, Tanaka, Kazuharu, Kukita, Goro, Kutomi, Keita, Saito, Koichi, Okuya, Akari, Takaya, Vitaly, Kochin, Takayuki, Kanaseki, Tomohide, Tsukahara, Yoshihiko, Hirohashi, Toshihiko, Torigoe, Koichi, Hirata, Noriyuki, Sato, Yasuaki, Tamura
Publikováno v:
European journal of immunology. 46(12)
To establish an effective cancer immunotherapy, it is crucial that cancer cells present a cancer-specific antigen in a hypoxic area, a hallmark of the tumor microenvironment. Here, we show the impact of hypoxia on MHC class I antigen presentation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7798cd00f4f3b74fe0cd95b3ccfdc8e5
https://pubmed.ncbi.nlm.nih.gov/27667124
https://pubmed.ncbi.nlm.nih.gov/27667124
Publikováno v:
Biochemical and Biophysical Research Communications. 386:202-206
In this study, we evaluated the signaling ability of SIGNR1 in murine macrophage-like RAW264.7 cells that stably expressed FLAG-tagged SIGNR1 (SIGNR1-FLAG). Cross-linking of SIGNR1-FLAG expressed on the cells by an anti-FLAG antibody induced JNK phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f06e6d2c55b3e8b73e76ca3cdae2c7
https://doi.org/10.1016/j.bbrc.2009.06.011
https://doi.org/10.1016/j.bbrc.2009.06.011
Autor:
Toshimitsu Kajiwara, Maki Numazaki, Chiaki Kato, Yu Abe, Hideaki Takagi, Mariko Ishii, Naoya Kojima
Publikováno v:
Glycobiology. 19:258-266
Resident peritoneal macrophages (PEMs) express SIGNR1 on the cell surface as a major mannose receptor. These cells also ingest oligomannose-coated liposomes (OMLs) in an oligomannose-dependent manner following intraperitoneal administration. Therefor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b124c47c53451e0bb4d95a51c4a4dc91
https://doi.org/10.1093/glycob/cwn128
https://doi.org/10.1093/glycob/cwn128
Publikováno v:
Journal of Autoimmunity. 29:164-173
Beta(2)-glycoprotein I (beta(2)GPI) is known as a major autoantigen for antiphospholipid antibodies. Our recent data show that binding of beta(2)GPI to oxidized low-density lipoprotein (oxLDL) or to liposomes containing anionic phospholipid(s) may fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb74fdfa470d96c2b51932a97c59a2c5
https://doi.org/10.1016/j.jaut.2007.07.003
https://doi.org/10.1016/j.jaut.2007.07.003
Autor:
Toshimitsu Kajiwara, Goro Kutomi, Yasuaki Tamura, Keita Saito, Tsutomu Tanaka, Noriyuki Sato, Takayuki Kanaseki, Yoshihiko Hirohashi, Koichi Hirata, Tomohisa Furuhata, Kazuharu Kukita, Koichi Okuya, Akari Takaya, Tomohide Tsukahara, Toshihiko Torigoe
Publikováno v:
Scopus-Elsevier
ERO1-α is an oxidizing enzyme that exists in the endoplasmic reticulum and is induced under hypoxia. It reoxidizes the reduced form of protein disulfide isomerase that has oxidized target proteins. We found that ERO1-α is overexpressed in a variety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12e06f23e91667f58a37bfadc8be957d
https://pubmed.ncbi.nlm.nih.gov/25870246
https://pubmed.ncbi.nlm.nih.gov/25870246
Autor:
Kazuharu Kukita, Tomoko Takamaru, Toshihiko Torigoe, Fukino Satomi, Tsutomu Tanaka, Yasuyo Suzuki, Toshimitsu Kajiwara, Hiroaki Shima, Noriyuki Sato, Koichi Hirata, Goro Kutomi, Tousei Ohmura, Yasuaki Tamura
Publikováno v:
Cancer Sci
Human endoplasmic reticulum oxidoreductin 1-α (hERO1-α) is an oxidizing enzyme that exists in the endoplasmic reticulum and its expression is augmented under hypoxia. It regulates a redox state of various kinds of protein through reoxidation of "cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4bf0777a3a4c782f995a83839c7f68
https://europepmc.org/articles/PMC7657143/
https://europepmc.org/articles/PMC7657143/
