Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Toshimitsu Fukumura"'
Autor:
Winn Aung, Zhao-Hui Jin, Takako Furukawa, Michael Claron, Didier Boturyn, Chizuru Sogawa, Atsushi B. Tsuji, Hidekatsu Wakizaka, Toshimitsu Fukumura, Yasuhisa Fujibayashi, Pascal Dumy, Tsuneo Saga
Publikováno v:
Molecular Imaging, Vol 12 (2013)
The purpose of this study was to develop a clinically relevant orthotopic xenotransplantation model of pancreatic cancer and to perform a preclinical evaluation of a new positron emission tomography (PET) imaging probe, 64 Cu-labeled cyclam-RAFT-c(-R
Externí odkaz:
https://doaj.org/article/67845eb1784e410a860d6316707620c0
Autor:
Yukie Yoshii, Takako Furukawa, Nobuyuki Oyama, Yoko Hasegawa, Yasushi Kiyono, Ryuichi Nishii, Atsuo Waki, Atsushi B Tsuji, Chizuru Sogawa, Hidekatsu Wakizaka, Toshimitsu Fukumura, Hiroshi Yoshii, Yasuhisa Fujibayashi, Jason S Lewis, Tsuneo Saga
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64570 (2013)
Fatty acid synthase (FASN) expression is elevated in several cancers, and this over-expression is associated with poor prognosis. Inhibitors of FASN, such as orlistat, reportedly show antitumor effects against cancers that over-express FASN, making F
Externí odkaz:
https://doaj.org/article/1f05c698d43041ccb4452ef9e7cbc8d2
Autor:
Takeaki Saijo, Jun Maeda, Takashi Okauchi, Jun-ichi Maeda, Yasunori Morio, Yasuhiro Kuwahara, Masayuki Suzuki, Nobuharu Goto, Toshimitsu Fukumura, Tetsuya Suhara, Makoto Higuchi
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42589 (2012)
A novel investigational antidepressant with high affinity for the serotonin transporter and the serotonin 1A (5-HT(1A)) receptor, called Wf-516 (structural formula: (2S)-1-[4-(3,4-dichlorophenyl)piperidin-1-yl]-3-[2-(5-methyl-1,3,4-oxadiazol-2-yl)ben
Externí odkaz:
https://doaj.org/article/69d91aaed4ba43c4bbce2afdcffb70e6
Autor:
Akiko Hatori, Joji Yui, Tomoteru Yamasaki, Lin Xie, Katsushi Kumata, Masayuki Fujinaga, Yuichiro Yoshida, Masanao Ogawa, Nobuki Nengaki, Kazunori Kawamura, Toshimitsu Fukumura, Ming-Rong Zhang
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45065 (2012)
PURPOSE: The translocator protein (18 kDa) (TSPO) is highly expressed on the bronchial and bronchiole epithelium, submucosal glands in intrapulmonary bronchi, pneumocytes and alveolar macrophages in human lung. This study aimed to perform positron em
Externí odkaz:
https://doaj.org/article/e52b38ac317940859f49cb580984f3f7
Autor:
Kenichi Odaka, Ichio Aoki, Junji Moriya, Kaoru Tateno, Hiroyuki Tadokoro, Jeff Kershaw, Tohru Minamino, Toshiaki Irie, Toshimitsu Fukumura, Issei Komuro, Tsuneo Saga
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25487 (2011)
BACKGROUND: Transplantation of mononuclear cells (MNCs) has previously been tested as a method to induce therapeutic angiogenesis to treat limb ischemia in clinical trials. Non-invasive high resolution imaging is required to track the cells and evalu
Externí odkaz:
https://doaj.org/article/f6a9827e12f44e1d9fd03aa11f2b5033
Autor:
Fukumura, Toshimitsu, Mori, Wakana, Ogawa, Masanao, Fujinaga, Masayuki, Ming-Rong, Zhang, Toshimitsu, Fukumura, Wakana, Mori, Masanao, Ogawa, Masayuki, Fujinaga, Zhang, Ming-Rong
Publikováno v:
Nuclear Medicine and Biology. 92:138-148
Carbon-11-labeled phosgene ([11C]phosgene, [11C]COCl2) is a useful labeling agent that connects two heteroatoms by inserting [11C]carbonyl (11C=O) function in carbamates, ureas, and carbonates, which are components of biologically important heterocyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::ffea7714755190874d3f1e4e042d2de3
https://repo.qst.go.jp/records/80191
https://repo.qst.go.jp/records/80191
Publikováno v:
Nuclear Medicine and Biology. 92:138-148
Carbon-11-labeled phosgene ([11C]phosgene, [11C]COCl2) is a useful labeling agent that connects two heteroatoms by inserting [11C]carbonyl (11C=O) function in carbamates, ureas, and carbonates, which are components of biologically important heterocyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4474f46422e66ce14a278bbb385c5d7
https://doi.org/10.1016/j.nucmedbio.2020.04.007
https://doi.org/10.1016/j.nucmedbio.2020.04.007
Autor:
Makoto Takei, Satoshi Shiomi, Kazunori Kawamura, Hiroki Hashimoto, Kenji Furutsuka, Masanao Ogawa, Ming-Rong Zhang, Toshimitsu Fukumura, Tomoya Fujishiro, Nobuki Nengaki, Masayuki Hanyu
Publikováno v:
Nuclear Medicine and Biology. 43:679-684
Introduction Recently, 6-[(1-cyclobutylpiperidin-4-yl)oxy]-1-(6-[ 11 C]methoxypyridin-3-yl)-3,4-dihydroquinolin-2(1 H )-one ([ 11 C]TASP457, [ 11 C] 2 ) has been developed as a novel PET ligand for histamine H 3 receptors in brain. [ 11 C] 2 is poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e66ec21e09ce49ce6623cdcc7765c60a
https://doi.org/10.1016/j.nucmedbio.2016.08.004
https://doi.org/10.1016/j.nucmedbio.2016.08.004
Autor:
Tomoyuki Ohya, Kotaro Nagatsu, Hisashi Suzuki, Masayuki Hanyu, Toshimitsu Fukumura, Katsuyuki Minegishi, Masami Fukada, Ming-Rong Zhang
Publikováno v:
Nuclear Medicine and Biology. 43:685-691
Introduction Copper-64 is an attractive radionuclide for positron emission tomography and is emerging as a radiotherapeutic agent. The demand of 64 Cu with low metallic impurities has increased because of its wide applications when incorporated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3436a346af8fef8a0ac3da6e85c61f5e
https://doi.org/10.1016/j.nucmedbio.2016.07.007
https://doi.org/10.1016/j.nucmedbio.2016.07.007
Autor:
Maiko Ono, Hiroshi Ito, Ryosuke Arakawa, Hitoshi Shimada, Hidehiko Takahashi, Makoto Higuchi, Kazuhiko Yanai, Yoko Eguchi, Hitoshi Shinotoh, Nobuyuki Okamura, Tetsuya Suhara, Fumitoshi Kodaka, Toshimitsu Fukumura, Michie Miyoshi, Harumasa Takano
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 41:745-754
The characteristic neuropathological changes in Alzheimer's disease (AD) are deposition of amyloid senile plaques and neurofibrillary tangles. The (18)F-labeled amyloid tracer, [(18)F]2-[(2-{(E)-2-[2-(dimethylamino)-1,3-thiazol-5-yl]vinyl}-1,3-benzox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de57ec491b875986c504ef7624df700c
https://doi.org/10.1007/s00259-013-2620-7
https://doi.org/10.1007/s00259-013-2620-7