Výsledky vyhledávání - "Toshimi Okada"

Akademický článek

ELF/VLF emission observation by Polar Patrol Balloons

Autor: Hisao Yamagishi, Taketoshi Miyake, Toshimi Okada, Akihiro Chino, Akira Kadokura, Yusuke Ebihara, Natsuo Sato, Hiroshi Takano

Publikováno v: Antarctic Record, Vol 50, Iss 2, Pp 115-131 (2006)

Circum-Antarctic balloons were launched from Syowa Station by the 44th Japanese Antarctic Research Experiment team in January 2003. Two balloons equipped with identical instruments were flown in formation around the Antarctic continent, in an attempt

Externí odkaz: https://doaj.org/article/f9aea7a04822476592bb1e98ac147201

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Akademický článek

Squalene synthase inhibitors suppress triglyceride biosynthesis through the farnesol pathway in rat hepatocytes

Autor: Hironobu Hiyoshi, Mamoru Yanagimachi, Masashi Ito, Nobuyuki Yasuda, Toshimi Okada, Hironori Ikuta, Daisuke Shinmyo, Keigo Tanaka, Nobuyuki Kurusu, Ichiro Yoshida, Shinya Abe, Takao Saeki, Hiroshi Tanaka

Publikováno v: Journal of Lipid Research, Vol 44, Iss 1, Pp 128-135 (2003)

We recently demonstrated that squalene synthase (S111111148) inhibitors reduce plasma triglyceride through an LDL receptor-independent mechanism in Watanabe heritable hyperlipidemic rabbits (Hiyoshi et al. 2001. Eur. J. Pharmacol. 431: 345–352). Th

Externí odkaz: https://doaj.org/article/68795c48eefe49edb03dfb9508144b44

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Supplementary Table S1 from E7090, a Novel Selective Inhibitor of Fibroblast Growth Factor Receptors, Displays Potent Antitumor Activity and Prolongs Survival in Preclinical Models

IC50 values for the inhibition of 93 human kinases by E7090.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727d71c17112f88bd1dc928969d95751
https://doi.org/10.1158/1535-7163.22506370

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Supplementary Figure S5 from E7090, a Novel Selective Inhibitor of Fibroblast Growth Factor Receptors, Displays Potent Antitumor Activity and Prolongs Survival in Preclinical Models

Western blot analysis of FGFR1 in human lung cancer cell lines harboring FGFR1 amplifications.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f0cbd7b4c4157ac6029645427248557
https://doi.org/10.1158/1535-7163.22506373

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Data from E7090, a Novel Selective Inhibitor of Fibroblast Growth Factor Receptors, Displays Potent Antitumor Activity and Prolongs Survival in Preclinical Models

The FGFR signaling pathway has a crucial role in proliferation, survival, and migration of cancer cells, tumor angiogenesis, and drug resistance. FGFR genetic abnormalities, such as gene fusion, mutation, and amplification, have been implicated in se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99edbb82e8632667d9aa9e5d5b108ead
https://doi.org/10.1158/1535-7163.c.6538381.v1

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Supplementary information from E7090, a Novel Selective Inhibitor of Fibroblast Growth Factor Receptors, Displays Potent Antitumor Activity and Prolongs Survival in Preclinical Models

Supplementary Table legends and Supplementary Figure legends.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c2fb8189ca1bb305f817e3eb3cfb0e
https://doi.org/10.1158/1535-7163.22506364.v1

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E7090, a Novel Selective Inhibitor of Fibroblast Growth Factor Receptors, Displays Potent Antitumor Activity and Prolongs Survival in Preclinical Models

Publikováno v: Molecular cancer therapeutics. 15(11)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a8ec020032fde1c69aa6790e1f3c5c1
https://pubmed.ncbi.nlm.nih.gov/27535969

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Low Frequency Generation and Detection of the Lamb Wave A0 Mode Using EMAT

Autor: Toshimi Okada, Songsong Li, Xiaoming Chen, Hongwei Dai

Publikováno v: IEEJ Transactions on Electronics, Information and Systems. 127:367-372

The study of using Electromagnetic Acoustic Transducer (EMAT) to generate and detect the low frequency Lamb wave A0 mode in the thin steel plate is described. On the base of analysis of dispersion curves, a Lorentz force type EMAT is designed to gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::16d39b0e8e67d4ec73997fb00e943449
https://doi.org/10.1541/ieejeiss.127.367

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E3024, 3-but-2-ynyl-5-methyl-2-piperazin-1-yl-3,5-dihydro-4H-imidazo[4,5-d]pyridazin-4-one tosylate, is a novel, selective and competitive dipeptidyl peptidase-IV inhibitor

Autor: Toshimi Okada, Nobuyuki Yasuda, Kazuto Yamazaki, Seiji Yoshikawa, Osamu Asano, Tadashi Nagakura, Osamu Takenaka, Richard Clark, Naruo Katsutani, Hironori Ikuta, Takashi Inoue, Isao Tanaka, Fumiyoshi Matsuura, Kazunobu Kira, Takao Saeki, Eita Emori

Publikováno v: European Journal of Pharmacology. 548:181-187

Dipeptidyl peptidase IV (DPP-IV) inhibitors are expected to become a useful new class of anti-diabetic agent. The aim of the present study is to characterize the in vitro and in vivo profile of E3024, 3-but-2-ynyl-5-methyl-2-piperazin-1-yl-3,5-dihydr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4594c4fb6af722e43dfac4a63e9e54c8
https://doi.org/10.1016/j.ejphar.2006.08.011

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Electromagnetic Acoustic Transducer for Generation and Detection of Guided Waves

Autor: Song Song Li, Xiaoming Chen, Toshimi Okada

Publikováno v: Japanese Journal of Applied Physics. 45:4541-4546

This paper presents a study of the use of low frequency electromagnetic acoustic transducers (EMATs) to generate and detect the single mode of Lamb waves in steel plates and pipes of different thickness. Using a small EMAT of the Lorentz force type,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5502e0ec496259535ef4203bad1c24bb
https://doi.org/10.1143/jjap.45.4541

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