Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Toshimasa Osaka"'
Autor:
Toshimasa Osaka
Publikováno v:
Neuroscience. 494:25-37
Autor:
Toshimasa, Osaka
Publikováno v:
Neuroscience. 494
This study aimed to re-examine the receptor subtype that mediates the fever-producing effects of prostaglandin E
Autor:
Toshimasa Osaka
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 95:652-660
2-Mercaptoacetate (MA) is an antimetabolic drug that inhibits the utilization of fatty acids as an energy source. The intravenous injection of MA (1.2 mmol·kg−1) elicited an increase in tail skin temperature and a decrease in body core temperature
Autor:
Toshimasa Osaka
Publikováno v:
Brain Research Bulletin. 116:73-80
Systemic or central administration of 2-deoxy- d -glucose (2DG), a competitive inhibitor of glucose utilization, induces hypothermia in awake animals and humans. This response is mediated by the central nervous system, though the neural mechanism inv
Autor:
Toshimasa Osaka
Publikováno v:
Neuroscience. 267:46-56
Hypoxia evokes a regulated decrease in the body core temperature (Tc) in a variety of animals. The neuronal mechanisms of this response include, at least in part, glutamatergic activation in the lateral preoptic area (LPO) of the hypothalamus. As the
Autor:
Naoto Kubota, Haruaki Kageyama, Seiji Shioda, Akira Senoo, Tetsuya Kubota, Hiroyuki Shimizu, Shuji Inoue, Noriko Ishizuka, Yoko Suzuki, Masatomo Mori, Akiyo Matsumoto, Toshimasa Osaka, Satoshi Hirako, Takashi Kadowaki, Hyounju Kim
Publikováno v:
Diabetes. 63:1637-1648
In obese humans and animals, adiponectin production and release in adipose tissue are downregulated by feedback inhibition, resulting in decreased serum adiponectin. We investigated adiponectin production and release in ventromedial hypothalamic (VMH
Autor:
Kahoru Sasaki, Nobuo Imazeki, Akira Senoo, Kaori Hayashi, Shuji Inoue, Yuri Kintaka, Noriko Ishizuka, Hiroyuki Shimizu, Tosei Takahashi, Yuichi Suzuki, Ryota Haba, Yoko Kobayashi, Yoko Suzuki, Masako Kako, Katsumi Arai, Toshimasa Osaka
Publikováno v:
Obesity Research & Clinical Practice. 6:e241-e247
Summary Background We have found previously that ventromedial hypothalamic lesions (VMH) enhance cell proliferation in the visceral organs through vagal hyperactivity in rats. The goal of the current study was to determine the characteristics and nat
Autor:
Yuichi Suzuki, Yuri Kintaka, Shuji Inoue, Yoko Suzuki, Ikiko Kinoshita, Nobuo Imazeki, Tosei Takahashi, Ryota Haba, Kahoru Sasaki, Noriko Ishizuka, Yoko Kobayashi, Akira Senoo, Hiroyuki Shimizu, Takeo Hashiguchi, Kaori Hayashi, Toshimasa Osaka, Masako Kako, Katsumi Arai, Katsuaki Tanaka
Publikováno v:
Obesity Research & Clinical Practice. 6:e225-e232
Summary In neural regulation of the endocrine pancreas, there is much evidence to suggest that vagal efferents alter insulin and glucagon secretion, but less information on the effects of vagal afferents. In this study, we investigated the role and f
Autor:
Takashi Miki, Toshimasa Osaka, Hiroyuki Shimizu, Masako Kako, Akira Senoo, Shuji Inoue, Yoko Suzuki, Noriko Ishizuka, Eun Young Lee, Kahoru Sasaki, Nobuo Imazeki
Publikováno v:
Brain Research. 1421:82-89
Liver has a high regenerative capacity and restores its mass and function shortly after partial hepatectomy through increased proliferation and metabolic modification of hepatocytes. The proliferation of hepatocytes can be triggered by its mass reduc
Autor:
Eiko Nakata, Yoko Suzuki, Yuri Kintaka, Toshimasa Osaka, Shuji Inoue, Takayoshi Kiba, Yasuhito Ishigaki
Publikováno v:
Experimental Biology and Medicine. 233:1368-1373
The intestinal epithelium is continuously renewed through a balance between cell proliferation and apoptosis. We identified genes of which expression profiles showed significant modulation, and we investigated the cellular mechanisms of this gene reg