Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Toshima Z Parris"'
Autor:
Malin Larsson, Nils Rudqvist, Johan Spetz, Emman Shubbar, Toshima Z Parris, Britta Langen, Khalil Helou, Eva Forssell-Aronsson
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0259429 (2021)
[This corrects the article DOI: 10.1371/journal.pone.0244098.].
Externí odkaz:
https://doaj.org/article/6bd69e114f5944fe86eace4f74852b02
Autor:
Slavica Janeva, MD, Chenyang Zhang, MSc, Anikó Kovács, PhD, Toshima Z Parris, PhD, Jennifer A Crozier, MD, Christopher M Pezzi, MD, Barbro Linderholm, PhD, Riccardo A Audisio, ProfPhD, Roger Olofsson Bagge, PhD
Publikováno v:
The Lancet. Healthy Longevity, Vol 1, Iss 3, Pp e117-e124 (2020)
Summary: Background: Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer associated with poor survival, in which adjuvant systemic treatments are limited to chemotherapy. Due to competing mortality risks and comorbidities, old
Externí odkaz:
https://doaj.org/article/6af47ccba0a947cfa1d847d41dad9238
Autor:
Malin Larsson, Nils Rudqvist, Johan Spetz, Emman Shubbar, Toshima Z Parris, Britta Langen, Khalil Helou, Eva Forssell-Aronsson
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0244098 (2020)
BackgroundRadioiodide (131I) is commonly used to treat thyroid cancer and hyperthyroidis.131I released during nuclear accidents, have resulted in increased incidence of thyroid cancer in children. Therefore, a better understanding of underlying cellu
Externí odkaz:
https://doaj.org/article/691608dc95d84e2f98dbb8ed6e2d3170
Autor:
Nils Rudqvist, Johan Spetz, Emil Schüler, Toshima Z Parris, Britta Langen, Khalil Helou, Eva Forssell-Aronsson
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171797 (2017)
Humans are exposed to 131I in medical diagnostics and treatment but also from nuclear accidents, and better knowledge of the molecular response in thyroid is needed. The aim of the study was to examine the transcriptional response in thyroid tissue 2
Externí odkaz:
https://doaj.org/article/39c276427c7a4c1f9cc8ad1ee11e72be
Autor:
Peter Larsson, Maria Cristina De Rosa, Benedetta Righino, Maxim Olsson, Bogdan Iulius Florea, Eva Forssell-Aronsson, Anikó Kovács, Per Karlsson, Khalil Helou, Toshima Z. Parris
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Computational pharmacogenomics can potentially identify new indications for already approved drugs and pinpoint compounds with similar mechanism-of-action. Here, we used an integrated drug repositioning approach based on transcriptomics data
Externí odkaz:
https://doaj.org/article/1b44d542d84c498ebb49958dfa4cacc1
Autor:
Peter Larsson, Maxim Olsson, Sithumini Sarathchandra, Anna Fäldt Beding, Eva Forssell-Aronsson, Anikó Kovács, Per Karlsson, Khalil Helou, Toshima Z. Parris
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract Repurposing of FDA-approved drugs is a quick and cost-effective alternative to de novo drug development. Here, we identify genes involved in bortezomib sensitivity, predict cancer types that may benefit from treatment with bortezomib, and ev
Externí odkaz:
https://doaj.org/article/cb8556dc4f164843a07201a962a40d0f
Autor:
Malin Druid, Emman Shubbar, Johan Spetz, Toshima Z. Parris, Britta Langen, Charlotte Ytterbrink, Evelin Berger, Khalil Helou, Eva Forssell-Aronsson
Publikováno v:
Radiation, Vol 4, Iss 2, Pp 149-166 (2024)
The physiological process of iodine uptake in the thyroid is used for 131I treatment of thyroid diseases. Children are more sensitive to radiation compared to adults and may react differently to 131I exposure. The aims of this study were to evaluate
Externí odkaz:
https://doaj.org/article/c8da68c9e399443299056ea3d7f2c5d3
Autor:
Emil Schüler, Maria Larsson, Toshima Z Parris, Martin E Johansson, Khalil Helou, Eva Forssell-Aronsson
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136204 (2015)
UnlabelledThe kidneys are one of the main dose-limiting organs in peptide receptor radionuclide therapy and due to large inter-individual variations in renal toxicity, biomarkers are urgently needed in order to optimize therapy and reduce renal tissu
Externí odkaz:
https://doaj.org/article/31e4c2c2f3b3471c9b26db6075dca1ff
Autor:
Nils Rudqvist, Johan Spetz, Emil Schüler, Toshima Z Parris, Britta Langen, Khalil Helou, Eva Forssell-Aronsson
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131686 (2015)
Background211At-labeled radiopharmaceuticals are potentially useful for tumor therapy. However, a limitation has been the preferential accumulation of released 211At in the thyroid gland, which is a critical organ for such therapy. The aim of this st
Externí odkaz:
https://doaj.org/article/041ef855452e48a4b9366bbee8dd23cd
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112645 (2014)
AimThe aim of this study was to investigate the variation of the miRNA expression levels in normal renal cortical tissue after 177Lu-octreotate administration, a radiopharmaceutical used for treatment of neuroendocrine cancers.MethodsFemale BALB/c nu
Externí odkaz:
https://doaj.org/article/897f7c020edb44e3a9282c5dc366a096