Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Toshiko Okuyama"'
Autor:
Kiyofumi Saijoh, Yoko Watanabe, Masafumi Tomita, Shigeko Fushimi, Koichiro Shimoya, Hironobu Katsuyama, Midori Katsuyama, Kunikazu Yamane, Toshiko Okuyama
Publikováno v:
Experimental and Therapeutic Medicine. 10:843-850
Vitamin K2 (VK2) has been used as a therapeutic agent for osteoporosis, since it has been suggested to be able to reduce the frequency of fractures by improving bone quality; however, bone turnover is strictly regulated by various cytokines and hormo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6312a9853b9b97afdf51be3d6f753831
https://doi.org/10.3892/etm.2015.2621
https://doi.org/10.3892/etm.2015.2621
Autor:
Shigeko Fushimi, Hironobu Katsuyama, Masayuki Nata, Yoko Watanabe, Takaki Ishikawa, Osamu Miyamoto, Toshiko Okuyama, Masafumi Tomita
Publikováno v:
Toxicology. 319:63-68
There is a close relationship between the central nervous system activity and bone metabolism. Therefore, methamphetamine (METH), which stimulates the central nervous system, is expected to affect bone turnover. The aim of this study was to investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a5c151eccd078f68836cab411de19f
https://doi.org/10.1016/j.tox.2014.01.014
https://doi.org/10.1016/j.tox.2014.01.014
Autor:
Yoko Watanabe, Hironobu Katsuyama, Takaki Ishikawa, Masayuki Nata, Masafumi Tomita, Kotaro Shinone, Toshiko Okuyama
Publikováno v:
Molecular Medicine Reports. 7:1786-1790
Methamphetamine (METH) abuse continues to be a worldwide problem, damaging the myocardial tissues, as well as the brains of individual users. In addition, stressors that increase drug cravings also contribute to cardiovascular diseases. The aim of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f649815dc3b464f81c7de5ae466125b7
https://doi.org/10.3892/mmr.2013.1408
https://doi.org/10.3892/mmr.2013.1408
Autor:
David Burgner, Masafumi Tomita, Ian G. Charles, Michihiro Matsuki, Toshiko Okuyama, Dominic P. Kwiatkowski, Lizhi Liu, Steve E. Humphries, Weiming Xu
Allelic frequencies of a (CCTTT)(n) pentanucleotide repeat in the NOS2A promoter region were determined in a total of 1393 unrelated individuals from five specific population groups in four continents: Africa, Europe, Asia, and the Caribbean. There w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8a9c777295eb3d61610115d55731bb
https://ora.ox.ac.uk/objects/uuid:f9bb3ce1-6dce-4083-bea4-2629f5e48742
https://ora.ox.ac.uk/objects/uuid:f9bb3ce1-6dce-4083-bea4-2629f5e48742
Autor:
Kazuo Hidaka, Toshiko Okuyama, Hironobu Katsuyama, Yasumitsu Nishimura, Masafumi Tomita, Takemi Otsuki, Yoshie Miura, Takaki Ishikawa
Publikováno v:
Toxicology. 231:200-209
Paraquat (PQ)-induced pulmonary toxicity is characterized by initial development of pulmonary edema, infiltration of inflammatory cells, and damage to the alveolar epithelium, which may progress to severe fibrosis. However, the exact role of PQ in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa5d140a048debfce8c863045e81b76
https://doi.org/10.1016/j.tox.2006.12.005
https://doi.org/10.1016/j.tox.2006.12.005
Publikováno v:
Free Radical Research. 38:821-829
Paraquat (PQ), a quaternary nitrogen herbicide, is highly toxic to humans and animals. Acute poisoning and death due to PQ exposure have been reported over the past few decades. Excessive production of oxygen free radicals has been proposed to play a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d8d7712852c66fff086a04566717f2
https://doi.org/10.1080/10715760410001713826
https://doi.org/10.1080/10715760410001713826
Publikováno v:
Forensic Science International. 127:119-127
We examined the complex short tandem repeat (STR) locus at the 3′-flanking region of the neurotensin receptor ( NTR ) gene. The polymorphism of this locus was first reported as a simple tetranucleotide repeat variation by Le et al. [1] , but it als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af11f765b3e2474e8d3f19581a652978
https://doi.org/10.1016/s0379-0738(02)00091-9
https://doi.org/10.1016/s0379-0738(02)00091-9
Autor:
Midori Katsuyama, Yoko Watanabe, Shigeko Fushimi, Kunikazu Yamane, Kiyofumi Saijoh, Masafumi Tomita, Hironobu Katsuyama, Toshiko Okuyama, Sri Ratna Rahayu
Publikováno v:
The FASEB Journal. 28
Vitamin K2 (VK2) has been used as a therapeutic agent for osteoporosis, and might reduce the frequency of fractures by improving bone quality. In the present study, effect of VK2 on bone turnover w...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82df713c8476d5c72bc7c6d13b5fd5b6
https://doi.org/10.1096/fasebj.28.1_supplement.1033.1
https://doi.org/10.1096/fasebj.28.1_supplement.1033.1
The role of nitric oxide in paraquat-induced cytotoxicity in the human A549 lung carcinoma cell line
Publikováno v:
Free Radical Research. 34:193-202
Paraquat (PQ) is a well-known pneumotoxicant that exerts its toxic effect by elevating intracellular levels of superoxide. In addition, production of pro-inflammatory cytokines has possibly been linked to PQ-induced inflammatory processes through rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adedc22bc7ad5844444f79d81402fe31
https://doi.org/10.1080/10715760100300181
https://doi.org/10.1080/10715760100300181
Autor:
Masayuki Nata, Takemi Otsuki, Hideo Ishizu, Fumio Moriya, Toshiko Okuyama, Hironobu Katsuyama, Yoko Watanabe, Kazuo Hidaka, Masafumi Tomita
Publikováno v:
Legal Medicine. 11:S437-S439
Stress-induced gastric mucosal injury is a common clinical entity. On the other hand, abuse of methamphetamine (MA) represents a growing social problem. MA users are frequently in stressful situations. In this study, we examined the effects of MA on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c9264065de8fcfee56963a08b879fc
https://doi.org/10.1016/j.legalmed.2009.01.020
https://doi.org/10.1016/j.legalmed.2009.01.020