Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Toshiko Hayatsu"'
1
Identification of mutagenic heterocyclic amines (IQ, Trp-P-1 and AαC) in the water of the Danube River
Autor: Siegfried Knasmüller, Gerhard Hietsch, Toshiko Hayatsu, Hans Steinkellner, Hikoya Hayatsu, Hiroyuki Kataoka, Sachiko Nishioka, Shizuo Narimatsu
Publikováno v: Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 466:27-35
Three mutagenic heterocyclic amines, 2-amino-3-methylimidazo-[4,5- f ]quinoline (IQ), 3-amino-1,4-dimethyl-5 H -pyrido[4,3- b ]indole (Trp-P-1) and 2-amino-9 H -pyrido[2,3- b ]indole (AαC), were isolated and identified in water from the Danube River
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389c279db81a9fb63c71c9e93f619423
https://doi.org/10.1016/s1383-5718(99)00235-1
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2
Protection against the bacterial mutagenicity of heterocyclic amines by purpurin, a natural anthraquinone pigment
Autor: Toshiko Hayatsu, Kazuo Nakayama, Hikoya Hayatsu, Sakae Arimoto-Kobayashi, Ken-ichi Fujita, Mikio Tada, Tetsuya Kamataki, Timothy H. Marczylo
Publikováno v: Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 444:451-461
Purpurin (1,2,4-trihydroxy-9,10-anthraquinone) is a naturally occurring anthraquinone pigment found in species of madder root. We have found that the presence of purpurin in bacterial mutagenicity assays is responsible for a marked inhibition of muta
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d4427adc2b54056d89158650c9d5c4
https://doi.org/10.1016/s1383-5718(99)00109-6
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3
Evaluation of blue-chitin column, blue-rayon hanging, and XAD-resin column techniques for concentrating mutagens from two Japanese rivers
Autor: Hiroshi Sakamoto, Toshiko Hayatsu, Hikoya Hayatsu, Takeshi Ohe
Publikováno v: Mutation Research/Genetic Toxicology. 371:79-85
Highly mutagenic water of the Katsura River, Kyoto, and moderately mutagenic of the Asahi River, Okayama, were used to evaluate the efficacy of three concentration techniques, the blue-chitin column, the blue-rayon hanging, and the XAD-2 column. Thes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c704967d308fe305c936c55e8c12f7c1
https://doi.org/10.1016/s0165-1218(96)90097-x
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4
Porphyrins as potential inhibitors against exposure to carcinogens and mutagens
Autor: Sakae Arimoto, Toshiko Hayatsu, Tomoe Negishi, Hikoya Hayatsu
Publikováno v: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 290:79-85
Studies have shown that there are many substances that can interfere with the actions of carcinogens and mutagens. Porphyrins, which often are constituents of diet, are a class of such inhibitors. Hemin can inhibit selectively the activity of mutagen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20de28fc2d8a025b41d2858e8dc6ae52
https://doi.org/10.1016/0027-5107(93)90035-e
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6
Inhibition of N-nitrosation of secondary amines in vitro by tea extracts and catechins
Autor: Toshiko Hayatsu, Tomoe Negishi, Hikoya Hayatsu, Kuniyuki Tanaka
Publikováno v: Mutation research. 412(1)
Inhibition of nitrite-mediated N-nitrosation of dimethylamine, morpholine and N-methylaniline by tea extracts and by 6 individual catechins in the extracts was studied. The inhibitions were detected by quantifying the nitrosamines formed. Eight diffe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf2be69f6911dd10e3b25a865f19d9e
https://pubmed.ncbi.nlm.nih.gov/9508368
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7
A short-column technique for concentrating mutagens/carcinogens having polycyclic structures
Autor: Hiroshi Sakamoto, Toshiko Hayatsu, Hikoya Hayatsu, Sakae Arimoto
Publikováno v: Analytical biochemistry. 235(2)
Copper phthalocyanine trisulfonate ( cpt ) is known to form complexes with polycyclic planar compounds and for that reason has been used in a rayon fiber-supported form as a ligand to selectively trap polycyclics, e.g., mutagenic/carcinogenic heteroc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24beef74b7919bb7713900265c36d4e8
https://pubmed.ncbi.nlm.nih.gov/8833326
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8
Suppressing effect of Lactobacillus casei administration on the urinary mutagenicity arising from ingestion of fried ground beef in the human
Autor: Toshiko Hayatsu, Hikoya Hayatsu
Publikováno v: Cancer letters. 73(2-3)
It is known that the ingestion of cooked meat which contains carcinogenic heterocyclic amines causes increase in urinary mutagenicity in humans. Using 6 healthy non-smokers, we examined the effect of 3-week oral administration of Lactobacillus casei
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4da02e76595c449141ca100f5de4de7
https://pubmed.ncbi.nlm.nih.gov/8221630
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10
Use of blue cotton for detection of mutagenicity in human feces excreted after ingestion of cooked meat
Autor: Yusuke Wataya, Toshiko Hayatsu, Hikoya Hayatsu
Publikováno v: Environmental Health Perspectives
Fried ground beef has been shown to contain mutagens, and the major mutagenic component has been identified as 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx). Mutagens in feces of three adult volunteers were fractionated by treatment of the fe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246c934ed2b0661227419d2017ddbed1
https://doi.org/10.1289/ehp.866731
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