Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Toshiko Eki"'
Publikováno v:
Drug Metabolism and Pharmacokinetics. 13:229-236
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::559d62b56c1646fc9d75549474b19e6f
https://doi.org/10.2133/dmpk.13.229
https://doi.org/10.2133/dmpk.13.229
Publikováno v:
Drug Metabolism and Pharmacokinetics. 13:237-251
The metabolism of NKH477 by the rat liver 9000×g supernatant was investigated. Also the metabolites of NKH477 in plasma, tissue, urine, feces and bile were analyzed after intravenous administration of 14C-NKH477 to rats and dogs or NKH477 to human.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd196a6b083205df8b3fa2640e37c187
https://doi.org/10.2133/dmpk.13.237
https://doi.org/10.2133/dmpk.13.237
Autor:
Kouwa Yamashita, Shin-ichi Ninomiya, Matsuo Takaichi, Yoshio Esumi, Tsuyoshi Irie, Shin-ichi Matsumoto, Miwa Ootubo, Atsushi Takao, Toshiko Eki, Hideaki Seki
Publikováno v:
Drug Metabolism and Pharmacokinetics. 13:221-228
The blood concentration, distribution and excretion of radioactivity were investigated in male rats after daily intravenous administration of 14C-NKH477 for 21 days. The effects of NKH477 on hepatic drug metabolizing enzyme system were also investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e9ca574c86051baba8f3a4ee3f2aa98
https://doi.org/10.2133/dmpk.13.221
https://doi.org/10.2133/dmpk.13.221
Publikováno v:
Drug Metabolism and Pharmacokinetics. 13:207-220
The pharmacokinetics, distribution and excretion of NKH477, a novel water-soluble forskolin derivative, improving acute cardiac failure, were investigated in rats and dogs after a single intravenous administration of 14C-labeled NKH477 and unlabeled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8005eb1464f36f6abf1090ad7a41636
https://doi.org/10.2133/dmpk.13.207
https://doi.org/10.2133/dmpk.13.207
Publikováno v:
ChemInform. 22
7-Acylmethylbicyclo[3.3.0]octanones were readily converted to bicyclo[3.2.1]oct-2-ene derivatives by treatment with BF 3 -etherate/ethylene glycol.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::893f7a1805ade0b9cf52227a1c9149f5
https://doi.org/10.1002/chin.199150080
https://doi.org/10.1002/chin.199150080
Publikováno v:
ChemInform. 23
By treatment with BF 3 -etheratelethylene glycol, cyclohexanone with a carbonyl function at the 2′-(or 3′-) position of γ-side chain underwent novel ring transformation to afford five- (or six-) membered rings, and the fused bicyclic rings (bicy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39cff1c64999967a5f232014f52e4216
https://doi.org/10.1002/chin.199239082
https://doi.org/10.1002/chin.199239082
Publikováno v:
Tetrahedron. 48:4517-4524
By treatment with BF 3 -etheratelethylene glycol, cyclohexanone with a carbonyl function at the 2′-(or 3′-) position of γ-side chain underwent novel ring transformation to afford five- (or six-) membered rings, and the fused bicyclic rings (bicy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fe84acac83fe6b896d3ef31d341c07b
https://doi.org/10.1016/s0040-4020(01)81224-2
https://doi.org/10.1016/s0040-4020(01)81224-2
Publikováno v:
Tetrahedron Letters. 32:515-516
7-Acylmethylbicyclo[3.3.0]octanones were readily converted to bicyclo[3.2.1]oct-2-ene derivatives by treatment with BF 3 -etherate/ethylene glycol.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3f4a6036c55ca191e26d452b6cc4e61
https://doi.org/10.1016/s0040-4039(00)79483-4
https://doi.org/10.1016/s0040-4039(00)79483-4