Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Toshiki Yamashiro"'
Publikováno v:
Chemistry, Vol 5, Iss 1, Pp 452-462 (2023)
C3–N1′ bond formation of bisindoles has been a great challenge due to the intrinsic reactivity of indoles as both C3 and N1-nucleophilic character. Herein, we demonstrate an C3–N1′ cross-coupling reaction of indoles using N-methoxyindoles as
Externí odkaz:
https://doaj.org/article/efe7a63d0b79492f992d6686f7c1770f
Publikováno v:
IDCases, Vol 8, Iss C, p 47 (2017)
Externí odkaz:
https://doaj.org/article/2a540d54b1664efdbad6abd393a99f4b
Publikováno v:
The Journal of Organic Chemistry. 88:3992-3997
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00c64526437b9f17c5382c1b91118ad4
https://doi.org/10.1021/acs.joc.3c00013
https://doi.org/10.1021/acs.joc.3c00013
Publikováno v:
Organic Chemistry Frontiers. 9:1897-1903
We report herein a formal cine-substitution/hydrolysis of 3-azidoindoles generated from 3-azido-2-methoxyindolines (AZINs). This protocol enables the introduction of various carboxylic acids and alcohols into indolin-3-ones at the C2-position, afford
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85bb1bef296631719122e641f8db8b7c
https://doi.org/10.1039/d2qo00048b
https://doi.org/10.1039/d2qo00048b
Publikováno v:
Journal of natural products. 85(8)
Echinosulfonic acid D, a sponge metabolite whose structure was recently reassigned, was synthesized for the first time. The key step is the double indolization of dimethylbarbituric acid using the umpolung indole reagent, followed by a hydrolysis/dec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b4f602f349d5b2de06a8df67a68b4e
https://pubmed.ncbi.nlm.nih.gov/35976728
https://pubmed.ncbi.nlm.nih.gov/35976728
Publikováno v:
Chemical Communications. 57:13381-13384
Use of 3-azidoindoles in organic synthesis remains a difficult task owing to their instabilities. Herein, we report a general and concise approach for tackling this problem by using 3-azidoindole surrogates. The surrogates are bench-stable, presumabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18405ab9bc6361c18de15064cdd32248
https://doi.org/10.1039/d1cc06033c
https://doi.org/10.1039/d1cc06033c
Publikováno v:
Chemical and Pharmaceutical Bulletin. 68:555-558
The regioselective synthesis of both 2- and 3-alkoxyindoles from a common intermediate, 2-alkoxy-3-bromoindolines (ROBIN), is described. The 2-alkoxyindoles are obtained by a base-promoted regioselective elimination of HBr from ROBIN, whereas the syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47725b84e92d94d137144ffeb1c5b7fe
https://doi.org/10.1248/cpb.c20-00135
https://doi.org/10.1248/cpb.c20-00135
Publikováno v:
Chemical Communications. 56:5139-5142
2,3-Dimethoxyindolines (DiMeOINs) have emerged as a latent electrophile in indium-catalyzed SNAr reactions. They are easily obtained from commercially available indoles and allowed access to 3-substituted indoles. The reaction proceeds via SNAr react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aab9e7a8d95343647084d2ef324fe410
https://doi.org/10.1039/d0cc01210f
https://doi.org/10.1039/d0cc01210f
Publikováno v:
Chemical communications (Cambridge, England). 56(70)
Enamines undergo α-indolization with ammonium salts in the presence of Et3N to form α-indolylketones. This is the first example of transition metal-, oxidant-, and fluorous solvent-free α-indolization of ketones. Key to the success of this conveni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70616102c721b1906b5513ede089e2d
https://pubmed.ncbi.nlm.nih.gov/32748921
https://pubmed.ncbi.nlm.nih.gov/32748921
Publikováno v:
Chemicalpharmaceutical bulletin. 68(6)
The regioselective synthesis of both 2- and 3-alkoxyindoles from a common intermediate, 2-alkoxy-3-bromoindolines (ROBIN), is described. The 2-alkoxyindoles are obtained by a base-promoted regioselective elimination of HBr from ROBIN, whereas the syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::407392d075e588b61131b6ffefe5388b
https://pubmed.ncbi.nlm.nih.gov/32475861
https://pubmed.ncbi.nlm.nih.gov/32475861