Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Toshiki Yabe-Wada"'
Publikováno v:
FEBS Open Bio, Vol 10, Iss 3, Pp 407-413 (2020)
Post‐transcriptional regulation of cytokine production is crucial to ensure appropriate immune responses. We previously demonstrated that poly‐rC‐binding protein‐1 (PCBP1) can act as a trans‐acting factor to stabilize transcripts encoding s
Externí odkaz:
https://doaj.org/article/98d501dccafd466eae7d2f1b5ef39c72
Autor:
Xinquan Yang, Toshiki Yabe-Wada, Jia Han, Fumiji Saito, Chie Ogasawara, Sohsuke Yamada, Nobuyuki Onai
Publikováno v:
International Immunology. 35:287-299
Intestinal macrophages with functional plasticity play essential roles in gut immune responses by increasing chemokines and cytokines, thereby contributing to the pathogenesis of inflammatory bowel disease (IBD). Poly(rC)-binding protein 1 (PCBP1), w
Publikováno v:
FEBS Open Bio, Vol 10, Iss 3, Pp 407-413 (2020)
FEBS Open Bio
FEBS Open Bio
Post‐transcriptional regulation of cytokine production is crucial to ensure appropriate immune responses. We previously demonstrated that poly‐rC‐binding protein‐1 (PCBP1) can act as a trans‐acting factor to stabilize transcripts encoding s
Crystal structure of the ligand‐free form of the Vps10 ectodomain of dimerized Sortilin at acidic pH
Publikováno v:
FEBS Letters. 592:2647-2657
Sortilin is a multifunctional sorting receptor involved in cytokine production in immune cells. To understand the mechanism of Sortilin-mediated cytokine trafficking, we determined the 2.45-Å structure of the dimerized Sortilin ectodomain (sSortilin
Autor:
Anna Nagai, Nobutaka Shimizu, Toshiki Yabe-Wada, Saya Kinjo, Ryutaro Mashimo, Kenji Kizawa, Hidenari Takahara, Masaki Unno, Shinya Saijo, Megumi Akimoto
Publikováno v:
Proceedings of the 3rd International Symposium of Quantum Beam Science at Ibaraki University "Quantum Beam Science in Biology and Soft Materials (ISQBSS2018)".
Autor:
Toshiki Yabe-Wada, Yoichiro Iwakura, Takashi Mochizuki, Shintaro Matsuba, Koichi Makimura, Kazushi Anzawa, Mari Higashino-Kameda, Kazuya Takeda, Hirohisa Toga, Akira Nakamura, Shinobu Saijo
Publikováno v:
Inflammation Research. 65:235-244
Hypersensitivity pneumonitis (HP) is a pulmonary disease caused by repeated exposure to various aspiration antigens, including bacteria and fungi. Although TLRs are known to be required for the generation of HP triggered by bacteria, the significance
Autor:
Tetsuya Sato, Toshiyuki Takai, Toshiki Yabe-Wada, Toshihiro Nukiwa, Akira Nakamura, Toshiaki Kikuchi, Kazuya Takeda, Mikita Suyama, Shintaro Matsuba
Publikováno v:
Frontiers in Immunology
Mast cells, basophils, and eosinophils are central effectors in allergic inflammatory disorders. These cells secrete abundant serine proteases as well as chemical mediators and cytokines; however, the expression profiles and functions of their endoge
Autor:
Kazuya Takeda, Toshiyuki Takai, Yoshiya Mitsuhashi, Toshiki Yabe-Wada, Toshihiro Nukiwa, Akira Nakamura, Shota Endo
Publikováno v:
Blood. 120:3256-3259
Plasmacytoid dendritic cells (PDCs) produce type I interferons (IFNs) in response to viral nucleic acids to exert antiviral immunity. However, PDCs are related to the progress and severity of autoimmune diseases, such as systemic lupus erythematosus,
Autor:
Shintaro Matsuba, Toshiki Yabe-Wada, Kazuya Takeda, Tetsuya Sato, Mikita Suyama, Toshiyuki Takai, Toshiaki Kikuchi, Toshihiro Nukiwa, Akira Nakamura
Publikováno v:
Frontiers in Immunology; 11/13/2017, p1-15, 15p