Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Toshiki Itoh"'
Autor:
Shinya Yuge, Koichi Nishiyama, Yuichiro Arima, Yasuyuki Hanada, Eri Oguri-Nakamura, Sanshiro Hanada, Tomohiro Ishii, Yuki Wakayama, Urara Hasegawa, Kazuya Tsujita, Ryuji Yokokawa, Takashi Miura, Toshiki Itoh, Kenichi Tsujita, Naoki Mochizuki, Shigetomo Fukuhara
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-25 (2022)
Chemical and mechanical cues coordinately regulate angiogenesis. Here, the authors show that blood flow-driven intraluminal pressure regulates wound angiogenesis. Findings indicate that TOCA family of F-BAR proteins act as actin regulators required f
Externí odkaz:
https://doaj.org/article/d6b4deab91e34aa196e28a5f5d3275e2
Autor:
Kaori Kanemaru, Makoto Shimozawa, Manabu Kitamata, Rikuto Furuishi, Hinako Kayano, Yui Sukawa, Yuuki Chiba, Takatsugu Fukuyama, Junya Hasegawa, Hiroki Nakanishi, Takuma Kishimoto, Kazuya Tsujita, Kazuma Tanaka, Toshiki Itoh, Junko Sasaki, Takehiko Sasaki, Kiyoko Fukami, Yoshikazu Nakamura
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Epithelial cells provide cell-cell adhesion to maintain the integrity of multicellular organisms. Here the authors show that phospholipid phosphatidylinositol (4,5)-bisphosphate is critical for the maintenance of epithelial characteristics.
Externí odkaz:
https://doaj.org/article/7823ce0d20e645f189c00d1084489ae8
Autor:
Kazuya Tsujita, Reiko Satow, Shinobu Asada, Yoshikazu Nakamura, Luis Arnes, Keisuke Sako, Yasuyuki Fujita, Kiyoko Fukami, Toshiki Itoh
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Changes in cell mechanics contribute to cancer cell dissemination. Here the authors show that high plasma membrane (PM) tension inhibits cancer dissemination by counteracting mechanosensitive BAR family protein assembly, while restoration of PM tensi
Externí odkaz:
https://doaj.org/article/cbe9da96697e4617972f9c2d3614eb29
Autor:
Tomoko Kamasaki, Yumi Miyazaki, Susumu Ishikawa, Kazuya Hoshiba, Keisuke Kuromiya, Nobuyuki Tanimura, Yusuke Mori, Motosuke Tsutsumi, Tomomi Nemoto, Ryota Uehara, Shiro Suetsugu, Toshiki Itoh, Yasuyuki Fujita
Publikováno v:
iScience, Vol 24, Iss 9, Pp 102994- (2021)
Summary: At the initial stage of carcinogenesis, cell competition often occurs between newly emerging transformed cells and the neighboring normal cells, leading to the elimination of transformed cells from the epithelial layer. For instance, when Ra
Externí odkaz:
https://doaj.org/article/fa958811e0e047c3bf59653c4f1490e6
Publikováno v:
Membranes, Vol 11, Iss 5, p 339 (2021)
We characterized the size, distribution, and fluidity of microdomains in a lipid bilayer containing phosphatidylinositol (PI) and revealed their roles during the two-dimensional assembly of a membrane deformation protein (FBP17). The morphology of th
Externí odkaz:
https://doaj.org/article/36cdb67828524dfa8f2a1585e3922c16
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 4, Pp 810-819 (2012)
Phosphoinositides (PI) play important regulatory roles in cell physiology. Localization and quantitation of PIs within the cell is necessary to understand their precise function. Currently, ectopic expression of green fluorescent protein (GFP)-fused
Externí odkaz:
https://doaj.org/article/fda1723c2b3441d5bc8a2eb0f5bfb5b6
Autor:
Hideaki Ando, Matsumi Hirose, Laura Gainche, Katsuhiro Kawaai, Benjamin Bonneau, Takeshi Ijuin, Toshiki Itoh, Tadaomi Takenawa, Katsuhiko Mikoshiba
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141569 (2015)
Phosphatidylinositol phosphate kinases (PIPKs) are lipid kinases that generate phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2), a critical lipid signaling molecule that regulates diverse cellular functions, including the activities of membrane chan
Externí odkaz:
https://doaj.org/article/112134259ee342e782b7d5aa18f05ee1
Autor:
Takashi Tsuruo, Kohei Miyazono, Tadaomi Takenawa, Toshiki Itoh, Ryohei Katayama, Atsuo Kurata, Shigeo Sato, Tomoko Oh-hara, Naoya Fujita, Emi Tokuda
Supplementary Figure Legends 1-5 from Casein Kinase 2–Interacting Protein-1, a Novel Akt Pleckstrin Homology Domain-Interacting Protein, Down-regulates PI3K/Akt Signaling and Suppresses Tumor Growth In vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4610e2948ac12a783fcbfcffffa30f92
https://doi.org/10.1158/0008-5472.22368245
https://doi.org/10.1158/0008-5472.22368245
Autor:
Tadaomi Takenawa, Miki Fukumoto, Yasuhiro Irino, Yukiko Takeuchi, Takeshi Ijuin, Junya Hasegawa, Toshiki Itoh, Emi Tokuda
PDF file - 263K, Supplementary Figure 4. Knockdown of PI4K variants.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b23ce42e85e0b732f5759216146e069
https://doi.org/10.1158/0008-5472.22398872
https://doi.org/10.1158/0008-5472.22398872
Autor:
Tadaomi Takenawa, Miki Fukumoto, Yasuhiro Irino, Yukiko Takeuchi, Takeshi Ijuin, Junya Hasegawa, Toshiki Itoh, Emi Tokuda
PDF file - 194K, Supplementary Figure 2. Quantification of phosphoinositides.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616159fdf8242c571638e8e29fd645a2
https://doi.org/10.1158/0008-5472.22398878.v1
https://doi.org/10.1158/0008-5472.22398878.v1