Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Toshiki Hyodo"'
Autor:
Haruka Miyazaki, Namiko Hoshi, Tsukasa Ishida, Chiharu Nishioka, Sachiko Ouchi, Daisuke Shirasaka, Tomoo Yoshie, Yoshinori Munetomo, Yoshio Sakamoto, Tatsuya Osuga, Saori Matsui, Toshiki Hyodo, Tamami Denda, Daisuke Watanabe, Makoto Ooi, Yuzo Kodama
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Not all patients with ulcerative colitis (UC) respond initially to treatment with biologic agents, and predicting their efficacy prior to treatment is difficult. Vedolizumab, a humanized monoclonal antibody against alpha 4 beta 7 (α4β7) in
Externí odkaz:
https://doaj.org/article/feac46e1e16e4db6837ec810e6c4879f
Autor:
Shunsuke Fujisawa, Junya Furukawa, Takuto Hara, Keiske Okada, Kouji Chiba, Yuzo Nakano, Toshiki Hyodo, Yoji Nagashima, Masato Fujisawa
Publikováno v:
Clinical Case Reports, Vol 11, Iss 11, Pp n/a-n/a (2023)
Key Clinical Message Renal cell carcinoma as a secondary malignant neoplasm is relatively rare; however, the possibility of secondary renal cell carcinoma following chemoradiotherapy for childhood nephroblastoma should be considered. Abstract The occ
Externí odkaz:
https://doaj.org/article/0c86693b01204a1e83ab7f08b0cb58ca
Autor:
Yoshiaki Kitsukawa, Chonji Fukumoto, Toshiki Hyodo, Yuske Komiyama, Ryo Shiraishi, Aya Koike, Shuma Yagisawa, Yosuke Kunitomi, Tomonori Hasegawa, Wataru Kotani, Kazuyuki Ishida, Takahiro Wakui, Hitoshi Kawamata
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3821 (2024)
Immune checkpoint inhibitors (ICIs), including anti-programmed cell death 1 ligand 1 (PD-L1) antibodies, are significantly changing treatment strategies for human malignant diseases, including oral cancer. Cancer cells usually escape from the immune
Externí odkaz:
https://doaj.org/article/cf7227ad3bec4005b172008212422667
Autor:
Toshiki Hyodo, Nobuyuki Kuribayashi, Chonji Fukumoto, Yuske Komiyama, Ryo Shiraishi, Ryouta Kamimura, Yuta Sawatani, Erika Yaguchi, Tomonori Hasegawa, Sayaka Izumi, Takahiro Wakui, Koh-ichi Nakashiro, Daisuke Uchida, Hitoshi Kawamata
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Mutations in p53 are common in human oral squamous cell carcinoma (OSCC). However, in previous analyses, only detection of mutant p53 protein using immunohistochemistry or mutations in some exons have been examined. Full length mutant p53 pr
Externí odkaz:
https://doaj.org/article/c3273cc919d246c78c8e65a976e85db2
Autor:
Chonji Fukumoto, Manabu Zama, Toshiki Hyodo, Ryo Shiraishi, Ryouta Kamimura, Shuma Yagisawa, Tomonori Hasegawa, Yuske Komiyama, Sayaka Izumi, Takahiro Wakui, Hitoshi Kawamata
Publikováno v:
Journal of International Medical Research, Vol 51 (2023)
The main symptom in primary syphilis is a small, painless, sore or ulcer called a chancre on the penis, vagina, or around the anus, although chancres can sometimes appear in the mouth or on the lips, fingers, or buttocks. We present the case of a man
Externí odkaz:
https://doaj.org/article/f381217696604341be377126220bf0ae
Autor:
Chonji Fukumoto, Shouhei Ogisawa, Masashi Tani, Toshiki Hyodo, Ryouta Kamimura, Yuta Sawatani, Tomonori Hasegawa, Yuske Komiyama, Atsushi Fujita, Takahiro Wakui, Yasuo Haruyama, Gen Kobashi, Hitoshi Kawamata
Publikováno v:
BMC Geriatrics, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background The status of oral cancer therapy in elderly patients in Japan, where ageing is rapidly progressing, may serve as a model for other countries with similar demographics. There is controversy over what kind of treatment should be ap
Externí odkaz:
https://doaj.org/article/2adb1d5acb574aa8b9cd1dc54e943378
Autor:
Yasuko Hyogo, Naomi Kiyota, Naoki Otsuki, Shunsuke Goto, Yoshinori Imamura, Naoko Chayahara, Masanori Toyoda, Ken-ichi Nibu, Toshiki Hyodo, Shigeo Hara, Hiroo Masuoka, Toshihiko Kasahara, Yasuhiro Ito, Akihiro Miya, Mitsuyoshi Hirokawa, Akira Miyauchi, Hironobu Minami
Publikováno v:
Case Reports in Oncology, Vol 11, Iss 3, Pp 735-741 (2018)
Standard therapy for radioactive iodine (RAI)-refractory differentiated thyroid cancer (DTC) is multi-targeted kinase inhibitors (m-TKIs), represented by sorafenib and lenvatinib. One of the main target molecules of m-TKIs is vascular endothelial gro
Externí odkaz:
https://doaj.org/article/b0d0c9d7672e45e898a65b676b42e0c5
Autor:
Chonji Fukumoto, Ryo Oshima, Yuta Sawatani, Ryo Shiraishi, Toshiki Hyodo, Ryouta Kamimura, Tomonori Hasegawa, Yuske Komiyama, Sayaka Izumi, Atsushi Fujita, Takahiro Wakui, Hitoshi Kawamata
Publikováno v:
Cancers, Vol 13, Iss 22, p 5843 (2021)
Background: The surveillance methods oral squamous cell carcinoma (OSCC) patients may be chosen by considering the risk for recurrence, and it is important to establish appropriate methods during the period in which latent/dormant cancer cells become
Externí odkaz:
https://doaj.org/article/4da3c54da4f94464b655713c6639c0e4
Autor:
Ryouta Kamimura, Daisuke Uchida, Shin-ichiro Kanno, Ryo Shiraishi, Toshiki Hyodo, Yuta Sawatani, Michiko Shimura, Tomonori Hasegawa, Maki Tsubura-Okubo, Erika Yaguchi, Yuske Komiyama, Chonji Fukumoto, Sayaka Izumi, Atsushi Fujita, Takahiro Wakui, Hitoshi Kawamata
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 10913 (2021)
TSC-22 (TGF-β stimulated clone-22) has been reported to induce differentiation, growth inhibition, and apoptosis in various cells. TSC-22 is a member of a family in which many proteins are produced from four different family genes. TSC-22 (correspon
Externí odkaz:
https://doaj.org/article/8c8151a8504c4f5c9762369fc826c3c7
Autor:
Yuta Sawatani, Yuske Komiyama, Koh-ichi Nakashiro, Daisuke Uchida, Chonji Fukumoto, Michiko Shimura, Tomonori Hasegawa, Ryouta Kamimura, Masayo Hitomi-Koide, Toshiki Hyodo, Hitoshi Kawamata
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6292 (2020)
Administration of cetuximab (C-mab) in combination with paclitaxel (PTX) has been used for patients with head and neck squamous cell carcinoma (SCC) clinically. In this study, we attempted to clarify the molecular mechanisms of the enhancing anticanc
Externí odkaz:
https://doaj.org/article/9aa895be0ca04626be704e3e5eba7e04