Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Toshiki Hiraki"'
Autor:
Takaaki Hikima, Toshiki Hiraki, Nobuo Kamiya, Tsutomu Mikawa, Shukuko Ikawa, Takeshi Shinohara, Naoto Arai, Takehiko Shibata, Wakana Iwasaki
Publikováno v:
Nucleic Acids Research
In all organisms, RecA-family recombinases catalyze homologous joint formation in homologous genetic recombination, which is essential for genome stability and diversification. In homologous joint formation, ATP-bound RecA/Rad51-recombinases first bi
Autor:
Masaaki Konishi, Chiaki Kato, Tadashi Maruyama, Yuji Hatada, Takayoshi Sekiguchi, Fumiyoshi Abe, Toshiki Hiraki
Publikováno v:
Journal of Bioscience and Bioengineering. 113:220-223
For efficient oxygen supply to pressurized culture, we developed a method using a highly pressurized membrane reactor with an air-saturated medium circulation system. The new method increased the cell growth of aerobic yeast approximately 20 folds la
Autor:
Fumiyoshi Abe, Takashi Ushimaru, Katsue Daicho, Toshiki Hiraki, Masaru Ueno, Masahiro Uritani, Nishiho Makino
Publikováno v:
FEMS Microbiology Letters. 298:218-227
Cholesterol (ergosterol in yeast) in conjunction with sphingolipids forms tight-packing microdomains, 'lipid rafts,' which are thought to be critical for intracellular protein sorting in eukaryotic cells. When the activity of Erg9 involved in the fir
Publikováno v:
Biochemistry. 48:8494-8504
Azole anitifungal drugs such as fluconazole inhibit 14alpha-demethylase. The mechanism of fluconazole action on the plasma membrane is assumed to be ergosterol depletion and accumulation of a toxic sterol, 14alpha-methyl-3,6-diol, that differs in C-6
Autor:
Fumiyoshi Abe, Toshiki Hiraki
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1788(3):743-752
Mutants of Saccharomyces cerevisiae defective in the late steps of ergosterol biosynthesis are viable but accumulate structurally altered sterols within the plasma membrane. Despite the significance of pleiotropic abnormalities in the erg mutants, li
Publikováno v:
Biochemistry. 43:8711-8717
A number of ligand binding studies of human adult hemoglobin (HbA) cross-linked between Lys 82beta(1) and Lys 82beta(2) with bis(3,5-dibromosalicyl)fumarate have been reported. The oxygen binding properties of native HbA, including the cooperativity
Publikováno v:
Eukaryotic cell. 12(7)
Cells of Saccharomyces cerevisiae express two tryptophan permeases, Tat1 and Tat2, which have different characteristics in terms of their affinity for tryptophan and intracellular localization. Although the high-affinity permease Tat2 has been well d
Autor:
Yuji Hatada, Katsuyuki Uematsu, Akihiro Tame, Taishi Tsubouchi, Kozue Mori, Keiko Usui, Shigeru Shimamura, Tadashi Maruyama, Toshiki Hiraki, Yasuhiro Shimane
Publikováno v:
International journal of systematic and evolutionary microbiology. 63(Pt 6)
A novel Gram-negative, aerobic, psychrotolerant, alkali-tolerant, heterotrophic and dimorphic prosthecate bacterium, designated strain TAR-001T, was isolated from deep-sea floor sediment in Japan. Cells of this strain had a dimorphic life cycle and d
Autor:
Tatsuo Kurihara, Fumiyoshi Abe, Keiko Usui, Toshiki Hiraki, Chiaki Kato, Yuichi Nogi, Jun Kawamoto
Publikováno v:
Biochimica et biophysica acta. 1818(3)
Shewanella violacea DSS12 is a psychrophilic piezophile that optimally grows at 30 MPa. It contains a substantial amount of eicosapentaenoic acid (EPA) in the membrane. Despite evidence linking increased fatty acid unsaturation and bacterial growth u
Autor:
Toshiki Hiraki, Fumiyoshi Abe
Publikováno v:
FEBS letters. 584(1)
Tryptophan permease Tat2 in Saccharomyces cerevisiae undergoes Rsp5-dependent degradation upon exposure to high hydrostatic pressure and it limits the growth of tryptophan auxotrophs. Overexpression of SNA3 encoding an endosomal/vacuolar protein poss