Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Toshiki Ebisudani"'
Autor:
Toshiki Ebisudani, Junko Hamamoto, Kazuhiro Togasaki, Akifumi Mitsuishi, Kai Sugihara, Taro Shinozaki, Takahiro Fukushima, Kenta Kawasaki, Takashi Seino, Mayumi Oda, Hikaru Hanyu, Kohta Toshimitsu, Katsura Emoto, Yuichiro Hayashi, Keisuke Asakura, Todd A. Johnson, Hideki Terai, Shinnosuke Ikemura, Ichiro Kawada, Makoto Ishii, Tomoyuki Hishida, Hisao Asamura, Kenzo Soejima, Hidewaki Nakagawa, Masayuki Fujii, Koichi Fukunaga, Hiroyuki Yasuda, Toshiro Sato
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112212- (2023)
Summary: Human lung cancer is a constellation of tumors with various histological and molecular properties. To build a preclinical platform that covers this broad disease spectrum, we obtained lung cancer specimens from multiple sources, including sp
Externí odkaz:
https://doaj.org/article/9ae31700ae9f4c67b5d8de1d1a09cd18
Autor:
Kei Haga, Reiko Takai-Todaka, Yuta Matsumura, Chihong Song, Tomomi Takano, Takuto Tojo, Atsushi Nagami, Yuki Ishida, Hidekazu Masaki, Masayuki Tsuchiya, Toshiki Ebisudani, Shinya Sugimoto, Toshiro Sato, Hiroyuki Yasuda, Koichi Fukunaga, Akihito Sawada, Naoto Nemoto, Kazuyoshi Murata, Takuya Morimoto, Kazuhiko Katayama
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1009542 (2021)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes the disease COVID-19 can lead to serious symptoms, such as severe pneumonia, in the elderly and those with underlying medical conditions. While vaccines are now available, t
Externí odkaz:
https://doaj.org/article/977c1f70bb2049c3a2f6faef7c65e0e7
Autor:
Kenzo Soejima, Koichi Fukunaga, Katsuhisa Horimoto, Kazuhiko Fukui, Yuichiro Hayashi, Ichiro Kawada, Shinnosuke Ikemura, Keita Masuzawa, Keigo Kobayashi, Toshiki Ebisudani, Junko Hamamoto, Harumi Kagiwada, Hideki Terai, Hiroyuki Yasuda, Tadashi Manabe
Supplementary Methods includes 4 methods: "Preparation of cell lysates for protein array", "Phosphorylation activity measurement on the array", "Estimation of active pathway by protein array" and "Software".
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d233b3303c70c81469d69eb825b277d0
https://doi.org/10.1158/1541-7786.22516806.v1
https://doi.org/10.1158/1541-7786.22516806.v1
Autor:
Kenzo Soejima, Koichi Fukunaga, Katsuhisa Horimoto, Kazuhiko Fukui, Yuichiro Hayashi, Ichiro Kawada, Shinnosuke Ikemura, Keita Masuzawa, Keigo Kobayashi, Toshiki Ebisudani, Junko Hamamoto, Harumi Kagiwada, Hideki Terai, Hiroyuki Yasuda, Tadashi Manabe
Supplementary Figures includes 6 figures. Supplementary Figure S1: Bypass pathway activation detected using a protein array confers resistance in PC9 cells. Supplementary Figure S2: IGF2-IGF1R activation contributes to acquired resistance to osimerti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beeaa6af83edf82946e99a0debddbc0c
https://doi.org/10.1158/1541-7786.22516809
https://doi.org/10.1158/1541-7786.22516809
Autor:
Kenzo Soejima, Koichi Fukunaga, Katsuhisa Horimoto, Kazuhiko Fukui, Yuichiro Hayashi, Ichiro Kawada, Shinnosuke Ikemura, Keita Masuzawa, Keigo Kobayashi, Toshiki Ebisudani, Junko Hamamoto, Harumi Kagiwada, Hideki Terai, Hiroyuki Yasuda, Tadashi Manabe
Supplementary Tables includes 8 tables. Supplementary Table S1: Patient-derived cancer cells: Patient and model characteristics. Supplementary Table S2: List of primer sequences used in quantitative RT-PCR for gene expression analysis. Supplementary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a544231f1c26f9afcb34b3b4e09e5d
https://doi.org/10.1158/1541-7786.22516803
https://doi.org/10.1158/1541-7786.22516803
Autor:
Kenzo Soejima, Koichi Fukunaga, Katsuhisa Horimoto, Kazuhiko Fukui, Yuichiro Hayashi, Ichiro Kawada, Shinnosuke Ikemura, Keita Masuzawa, Keigo Kobayashi, Toshiki Ebisudani, Junko Hamamoto, Harumi Kagiwada, Hideki Terai, Hiroyuki Yasuda, Tadashi Manabe
EGFR-mutated lung cancer accounts for a significant proportion of lung cancer cases worldwide. For these cases, osimertinib, a third-generation EGFR tyrosine kinase inhibitor, is extensively used as a first-line or second-line treatment. However, lun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a314fd67cc3a05a181338e76f379fd51
https://doi.org/10.1158/1541-7786.c.6541491
https://doi.org/10.1158/1541-7786.c.6541491
Data from Upregulation of FGF9 in Lung Adenocarcinoma Transdifferentiation to Small Cell Lung Cancer
Autor:
Koichi Fukunaga, Kenzo Soejima, Tomoko Betsuyaku, David M. Ornitz, Hideo Watanabe, Takashi Kohno, Susumu S. Kobayashi, Ahmed E. Hegab, Yuichiro Hayashi, Katsuya Tsuchihara, Hisao Asamura, Takashi Ohtsuka, Morio Nakamura, Katsuhiko Naoki, Ichiro Kawada, Shinnosuke Ikemura, Mari Ozaki, Takahiro Fukushima, Toshiki Ebisudani, Akifumi Mitsuishi, Taro Shinozaki, Tadashi Manabe, Keita Masuzawa, Tetsuo Tani, Keiko Ohgino, Daisuke Arai, Sachiyo Mimaki, Takashi Kamatani, Shigemichi Hirose, Tae-Jung Kim, Katsura Emoto, Hideki Terai, Junko Hamamoto, Hiroyuki Yasuda, Kota Ishioka
Transdifferentiation of lung adenocarcinoma to small cell lung cancer (SCLC) has been reported in a subset of lung cancer cases that bear EGFR mutations. Several studies have reported the prerequisite role of TP53 and RB1 alterations in transdifferen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddaf045411379d63d8936cc785bb6772
https://doi.org/10.1158/0008-5472.c.6513297.v1
https://doi.org/10.1158/0008-5472.c.6513297.v1
Autor:
Koichi Fukunaga, Kenzo Soejima, Tomoko Betsuyaku, David M. Ornitz, Hideo Watanabe, Takashi Kohno, Susumu S. Kobayashi, Ahmed E. Hegab, Yuichiro Hayashi, Katsuya Tsuchihara, Hisao Asamura, Takashi Ohtsuka, Morio Nakamura, Katsuhiko Naoki, Ichiro Kawada, Shinnosuke Ikemura, Mari Ozaki, Takahiro Fukushima, Toshiki Ebisudani, Akifumi Mitsuishi, Taro Shinozaki, Tadashi Manabe, Keita Masuzawa, Tetsuo Tani, Keiko Ohgino, Daisuke Arai, Sachiyo Mimaki, Takashi Kamatani, Shigemichi Hirose, Tae-Jung Kim, Katsura Emoto, Hideki Terai, Junko Hamamoto, Hiroyuki Yasuda, Kota Ishioka
Supplementary Table S1. Mutation signature analysis. Supplementary Table S2. Baseline characteristics of the transdifferentiated SCLC patients included in this study. Supplementary Table S3. Intensity of EGFR and Ki67 staining in lung cancer tissues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f942e0b008c8e2dd7ed6842636f4dcf
https://doi.org/10.1158/0008-5472.22429245
https://doi.org/10.1158/0008-5472.22429245
Autor:
Junko Hamamoto, Harumi Kagiwada, Keigo Kobayashi, Yuichiro Hayashi, Koichi Fukunaga, Hiroyuki Yasuda, Hideki Terai, Kazuhiko Fukui, Tadashi Manabe, Katsuhisa Horimoto, Ichiro Kawada, Shinnosuke Ikemura, Kenzo Soejima, Toshiki Ebisudani, Keita Masuzawa
Publikováno v:
Molecular Cancer Research. 18:549-559
EGFR-mutated lung cancer accounts for a significant proportion of lung cancer cases worldwide. For these cases, osimertinib, a third-generation EGFR tyrosine kinase inhibitor, is extensively used as a first-line or second-line treatment. However, lun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1baf510bc64917d371e7684004b87c8f
https://doi.org/10.1158/1541-7786.mcr-19-0956
https://doi.org/10.1158/1541-7786.mcr-19-0956
Autor:
Toshiki Ebisudani, Akiko Tateishi, Masafumi Misawa, Kazuei Hoshi, Yu Oyama, Kei Nakashima, Masahiro Aoshima
Publikováno v:
Internal Medicine
Pulmonary tumor thrombotic microangiopathy (PTTM) is a complication characterized by dyspnea, pulmonary hypertension, and occasionally sudden death. We encountered a man who developed PTTM and had an inhalation history of chemical herbicides and abno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2918c50fb4e68300897c5a7b4d64990
https://doi.org/10.2169/internalmedicine.1796-18
https://doi.org/10.2169/internalmedicine.1796-18