Výsledky vyhledávání - "Toshikazu HADA"

Involvement of hepatoma-derived growth factor in the growth inhibition of hepatocellular carcinoma cells by vitamin K2

Autor: T. Yamamoto, Hideji Nakamura, Hiroko Iijima, Yoshinori Iwata, Toshikazu Hada, Soji Shimomura, Shuhei Nishiguchi, Masaki Saito, Weidong Liu, Shohei Yoshikawa, Hiroyasu Imanishi, Hirayuki Enomoto, Noritoshi Koh, Ke Cao

Publikováno v: Journal of Gastroenterology. 44:228-235

Vitamin K(2) has been reported to suppress the growth of human hepatocellular carcinoma (HCC) in vitro and hepatocarcinogenesis in hepatitis C virus (HCV)-related cirrhosis in vivo. Hepatoma-derived growth factor (HDGF) is a unique nuclear targeting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3fce6cf5c67dad48931dfc031ce7ebc
https://doi.org/10.1007/s00535-008-2304-4

Zobrazit plný text záznamu

Successful pediatric living donor liver transplantation from carrier to carrier of hereditary butyrylcholinesterase variant

Autor: Takeshi Saito, Hideo Kawarasaki, Masami Ohmori, Weidong Liu, Toshikazu Hada, Koichi Mizuta, Koichi Sakamoto, T. Fujiwara, Yoshikazu Yasuda, Yukihiro Sanada, Shuhei Nishiguchi, Youichi Kawano, Satoshi Egami, Yuka Takatsuka, Shuji Hisikawa

Publikováno v: Pediatric Transplantation. 11:694-697

Hypocholinesterasemia is often observed clinically, especially in various liver diseases. Not well known, however, is the fact that some patients have a hereditary BChE variant. Little has been reported on liver transplants associated with this hered

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6454f3dc76b7a1c471eec6f7e591e35e
https://doi.org/10.1111/j.1399-3046.2007.00750.x

Zobrazit plný text záznamu

Vitamin K2 inhibits the proliferation of HepG2 cells by up-regulating the transcription of p21 gene

Autor: Toshikazu Hada, Naoto Ikeda, Shuhei Nishiguchi, Soji Shimomura, Weidong Liu, Masaki Saito, Tetsuo Yamamoto, T. Yamamoto, Masao Ohno, Hideji Nakamura, Toshiyuki Sakai, Naoki Hara, Hiroyasu Imanishi

Publikováno v: Hepatology Research. 37:360-365

Aim: Vitamin K2 has been reported to inhibit the growth of human hepatocellular carcinoma (HCC) in vitro and suppress hepatocarcinogenesis in vivo. However, its inhibitory mechanism has not yet been clarified. Methods: Different concentrations of vit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d1f69a3e25483a556d87fe41f2c114
https://doi.org/10.1111/j.1872-034x.2007.00058.x

Zobrazit plný text záznamu

Triple therapy of initial high-dose interferon with ribavirin and amantadine for patients with chronic hepatitis C

Autor: Eijiro Hayashi, Hirayuki Enomoto, Hiroyuki Ogawa, Toshikazu Hada, Hirokazu Uyama, Norio Hayashi, Yorihide Okuda, Kenya Yoshida, Mitsunari Yamamoto, Hideji Nakamura

Publikováno v: Hepatology Research. 37:325-330

Aims: We previously reported the potential effect of combination therapy of an initial high-dose interferon (IFN) and amantadine on the eradication of HCV-RNA in patients with chronic hepatitis C. The additive effects of amantadine on interferon and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67478a63598a5d7ef21d6a42b72305a8
https://doi.org/10.1111/j.1872-034x.2007.00044.x

Zobrazit plný text záznamu

Hemochromatosis with Mutation of the Ferroportin 1 (IREG1) Gene

Autor: Naoto Ikeda, Tetsuo Yamamoto, Toshikazu Hada, S. Shimomura, Naoki Hara, Hiroyasu Imanishi, Masao Ohno, Weidong Liu, Yuna Iwamoto, Masaki Saito, Hideji Nakamura

Publikováno v: Internal Medicine. 44:285-289

The HFE, H ferritin, TFR2, and ferroportin 1 genes of a Japanese patient diagnosed as having hemochromatosis were amplified by PCR and sequenced. A novel mutation in the ferroportin 1 was found in the patient. It was located in the noncoding region o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57fde376b708cd1d4377155cf92b0884
https://doi.org/10.2169/internalmedicine.44.285

Zobrazit plný text záznamu

Involvement of Interleukin-18 in Acute Graft-Versus-Host Disease in Mice

Autor: Haruki Okamura, Hisayuki Itoi, Nobuyuki Terada, Hiroko Tsutsui, Toshikazu Hada, Yoshihiro Fujimori, Eizo Kakishita, Kenji Nakanishi, Ayako Sugihara, Kiyoshi Matsui, Hiroshi Hara

Publikováno v: Transplantation. 78:1245-1250

BACKGROUND Interleukin (IL)-18 stimulates T helper 1 (Th1)-mediated immune responses and the development of cytotoxic T lymphocytes (CTLs). Antihost CTLs are major effectors in acute graft-versus-host disease (aGvHD), a potentially fatal complication

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4221662e9eb0fb1a89ca1f34ac028da
https://doi.org/10.1097/01.tp.0000137934.25190.b9

Zobrazit plný text záznamu

IL-18 together with anti-CD3 antibody induces human Th1 cells to produce Th1- and Th2-cytokines and IL-8

Autor: Toshikazu Hada, Hitomi Hata, Kenji Nakanishi, Tomohiro Yoshimoto, Nobuki Hayashi

Publikováno v: International Immunology. 16:1733-1739

Although IL-18 was initially regarded as a factor that enhances IFN-gamma production from Th1 cells, later studies revealed its potential to induce Th2 cytokine production from T cells, NK cells and basophils/mast cells. Very recently, we demonstrate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94c60726dc41c06b7706b97dfa0b001
https://doi.org/10.1093/intimm/dxh174

Zobrazit plný text záznamu

Peroxisome proliferator-activated receptor γ ligands, 15-deoxy-Δ12,14-prostaglandin J2, and ciglitazone, induce growth inhibition and cell cycle arrest in hepatic oval cells

Autor: Hiroyasu Imanishi, Toshikazu Hada, Toshihiro Sugiyama, Hideji Nakamura, Takayuki Morisaki, Jidong Cheng, Weidong Liu

Publikováno v: Biochemical and Biophysical Research Communications. 322:458-464

There is growing evidence to show that hepatic oval cells contribute to liver regeneration, dysplastic nodule formation, and hepato-carcinogenesis. Peroxisome proliferator-activated receptors (PPARs) and their ligands play an important role in cell g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b655d7a98839ccefecd44225f430803
https://doi.org/10.1016/j.bbrc.2004.07.133

Zobrazit plný text záznamu

Involvement of cell cycle regulatory proteins and MAP kinase signaling pathway in growth inhibition and cell cycle arrest by a selective cyclooxygenase 2 inhibitor, etodolac, in human hepatocellular carcinoma cell lines

Autor: Hideji Nakamura, Weidong Liu, Takayuki Morisaki, Toshikazu Hada, Jidong Cheng, Hiroyasu Imanishi, Kazuya Higashino

Publikováno v: Cancer Science. 95:666-673

Recent studies have shown that selective cyclooxygenase-2 (COX-2) inhibitors induce growth inhibition and cell cycle arrest in hepatocellular carcinoma (HCC) cell lines. However, the mechanism by which COX-2 inhibitors regulate the cell cycle and whe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f302f8898e445fb2ced066783576e1f
https://doi.org/10.1111/j.1349-7006.2004.tb03327.x

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání