Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Toshikatsu Tamai"'
Autor:
Miyabi Miura, Michiko Nishino, Kazunori Kawaguchi, Shihui Li, Tetsuro Shimakami, Toshikatsu Tamai, Hidetoshi Nakagawa, Takeshi Terashima, Noriho Iida, Hajime Takatori, Kuniaki Arai, Yoshio Sakai, Tatsuya Yamashita, Masao Honda, Shuichi Kaneko, Eishiro Mizukoshi, Taro Yamashita
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0299424 (2024)
Mutations in the non-structural protein regions of hepatitis C virus (HCV) are a cause of a non-sustained virological response (SVR) to treatment with direct-acting antivirals (DAAs) for chronic hepatitis; however, there are non-SVR cases without the
Externí odkaz:
https://doaj.org/article/fbb49edf38e544e891985400295f84b7
Autor:
Eishiro Mizukoshi, Hidetoshi Nakagawa, Toshikatsu Tamai, Masaaki Kitahara, Kazumi Fushimi, Kouki Nio, Takeshi Terashima, Noriho Iida, Kuniaki Arai, Tatsuya Yamashita, Taro Yamashita, Yoshio Sakai, Masao Honda, Shuichi Kaneko
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
The success of peptide vaccine treatment in cancer relies on the build-up of an efficient cytotoxic T cell response against the tumour antigen. Authors show here that tumour-specific memory CD8 T cells are able to persist and possibly even proliferat
Externí odkaz:
https://doaj.org/article/c46bdf6b393e4d2dbd7e95f80497ad0c
Autor:
Takayoshi Shirasaki, Satoshi Yamagoe, Tetsuro Shimakami, Kazuhisa Murai, Ryu Imamura, Kiyo-Aki Ishii, Hiroaki Takayama, Yukako Matsumoto, Natsumi Tajima-Shirasaki, Naoto Nagata, Ryogo Shimizu, Souma Yamanaka, Atsushi Abe, Hitoshi Omura, Kazunori Kawaguchi, Hikari Okada, Taro Yamashita, Tomoki Yoshikawa, Kazuhiro Takimoto, Motoko Taharaguchi, Shogo Takatsuka, Yoshitsugu Miyazaki, Toshikatsu Tamai, Yamato Tanabe, Makoto Kurachi, Yasuhiko Yamamoto, Shuichi Kaneko, Kunio Matsumoto, Toshinari Takamura, Masao Honda
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The innate antiviral immune response is an important defense against infection. Here, the authors show that leukocyte cell-derived chemotaxin 2 (LECT2) promotes RIG-I-mediated innate immune responses by preventing its degradation, and inhibits lympho
Externí odkaz:
https://doaj.org/article/255dc45f68324700bcce168ab5fc087f
Autor:
Taro Yamashita, Shuji Osawa, Kunio Ota, Takahiro Minami, Yuma Morisaki, Yutaro Takahashi, Tomoya Itatani, Satoshi Hara, Toshikatsu Tamai, Makoto Fujiu, Hideki Nomura, Rie Okamoto
Publikováno v:
Medical Education Online, Vol 26, Iss 1 (2021)
Online classes have been provided for health-care pre-licensure learners during the novel coronavirus disease 2019 pandemic. The purpose of this study was to evaluate the utility of online group work in interprofessional education. A total of 209 stu
Externí odkaz:
https://doaj.org/article/247ca746328247b1b8886bab751818a2
Autor:
Rika Horii, Kuniaki Arai, Eishiro Mizukoshi, Masao Honda, Shuichi Kaneko, Noriho Iida, Takeshi Terashima, Tatsuya Yamashita, Tetsuro Shimakami, Toshikatsu Tamai, Yoshio Sakai, Masaaki Kitahara, Taro Yamashita, Kazuki Nagai, Kazunori Kawaguchi
Publikováno v:
Kanzo. 62:413-419
Autor:
Kuniaki Arai, Masao Honda, Yoshio Sakai, Hikari Okada, Eishiro Mizukoshi, Tatsuya Yamashita, Takeshi Terashima, Noriho Iida, Kazumi Fushimi, Hidetoshi Nakagawa, Toshikatsu Tamai, Shuichi Kaneko, Taro Yamashita, Masaaki Kitahara, Atsushi Yonejima
Publikováno v:
Hepatology. 70:25-39
Dendritic cells (DCs) are antigen-presenting cells with a central role in host immune response. This study analyzed gene expression and DC function in hepatitis B virus (HBV) patients, functions impaired because of HBV, and identified the genes relat
Autor:
Kazumi Fushimi, Toshikatsu Tamai, Masao Honda, Taro Yamashita, Tatsuya Yamashita, Noriho Iida, Kuniaki Arai, Takeshi Terashima, Yuki Inada, Takuya Seike, Shuichi Kaneko, Eishiro Mizukoshi, Masaaki Kitahara
Publikováno v:
Hepatology. 69:653-665
Host antitumor immune responses may be different between hepatocellular carcinoma (HCC) caused by metabolic disorders and HCC associated with hepatitis virus infection. In this study, we examined the immune response of tumor-associated antigen (TAA)-
Peptide vaccine-treated, long-term surviving cancer patients harbor self-renewing tumor-specific CD8
Autor:
Eishiro Mizukoshi, Hidetoshi Nakagawa, Toshikatsu Tamai, Masaaki Kitahara, Kazumi Fushimi, Kouki Nio, Takeshi Terashima, Noriho Iida, Kuniaki Arai, Tatsuya Yamashita, Taro Yamashita, Yoshio Sakai, Masao Honda, Shuichi Kaneko
Publikováno v:
Nature communications. 13(1)
The behaviors and fates of immune cells in cancer patients, such as dysfunction and stem-like states leading to memory formation in T cells, are in intense focus of investigation. Here we show, by post hoc analysis of peripheral blood lymphocytes of
Autor:
Makoto Fujiu, Rie Okamoto, Yuma Morisaki, Kunio Ota, Toshikatsu Tamai, Takahiro Minami, Satoshi Hara, Shuji Osawa, Taro Yamashita, Tomoya Itatani, Hideki Nomura, Yutaro Takahashi
Publikováno v:
Medical Education
article-version (VoR) Version of Record
Medical Education Online, Vol 26, Iss 1 (2021)
article-version (VoR) Version of Record
Medical Education Online, Vol 26, Iss 1 (2021)
Online classes have been provided for health-care pre-licensure learners during the novel coronavirus disease 2019 pandemic. The purpose of this study was to evaluate the utility of online group work in interprofessional education. A total of 209 stu
Autor:
Taro Yamashita, Tatsuya Yamashita, Eishiro Mizukoshi, Noriho Iida, Tetsuro Shimakami, Kazuya Kitamura, Kuniaki Arai, Toshikatsu Tamai, Masaaki Kitahara, Kazumi Fushimi, Takeshi Terashima, Masao Honda, Masashi Kumagai, Shuichi Kaneko, Yoshio Sakai
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
α-Fetoprotein (AFP) is considered a good target for immunotherapy strategies against hepatocellular carcinoma (HCC); however, no immunodominant AFP-derived MHC class II-restricted helper T-lymphocyte (HTL) epitope has been reported. Therefore, we id