Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Toshikatsu Nakashima"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 94, Iss 1, Pp 31-38 (2004)
To elucidate the anti-inflammatory action of nicotine-induced corticosterone elevation on the passive skin Arthus reaction (PSAR), we investigated the inflammatory process in the PSAR. The polymorphonuclear leukocyte (PMNs) infiltration was observed
Externí odkaz:
https://doaj.org/article/186b44be2aa149a8988bf38b3bbbde63
Autor:
Norikazu Ohno, Takeshi Tanaka, Taizo Kita, Kaoru Kubo, Keiji Shimada, Yukio Yonetani, Noboru Konishi, Toshikatsu Nakashima
Publikováno v:
Journal of Pharmacological Sciences, Vol 94, Iss 3, Pp 287-296 (2004)
The present study was conducted to evaluate the contribution of endothelin (ET) to the pharmacodynamic response to chronic cigarette smoke in spontaneously hypertensive rats (SHR). The contribution of ET was studied consequent to the hemodynamic resp
Externí odkaz:
https://doaj.org/article/4e8b495216b144b8ad8bb27e8cdce0df
Publikováno v:
Journal of Pharmacological Sciences, Vol 92, Iss 3, Pp 178-195 (2003)
Methamphetamine (METH)-induced neurotoxicity is characterized by a long-lasting depletion of striatal dopamine (DA) and serotonin as well as damage to striatal dopaminergic and serotonergic nerve terminals. Several hypotheses regarding the mechanism
Externí odkaz:
https://doaj.org/article/40ea6c2d3787440c99ee14fd3327f4a9
Development of High Accurate and High-Speed, Worm Form Rolling Technology with V Character Wedge Die
Publikováno v:
Journal of the Japan Society for Technology of Plasticity. 51:1130-1134
Autor:
Toshikatsu Nakashima, Md. Joynal Abdin, Tomoya Kitayama, Katsuya Morita, Toshihiro Dohi, Norimitsu Morioka, Shigeo Kitayama
Publikováno v:
Life Sciences. 80(1):9-16
The activation of cholinergic pathways by nicotine elicits various physiological and pharmacological effects in mammals. For example, the stimulation of nicotinic acetylcholine receptors (nAChRs) leads to an antinociceptive effect. However, it remain
Systemic Meloxicam Reduces Tactile Allodynia Development After L5 Single Spinal Nerve Injury in Rats
Publikováno v:
Regional Anesthesia and Pain Medicine. 30:351-355
Background Although recent evidence suggests that cyclooxygenase-2 (COX-2) may contribute to the development and management of neuropathic pain, the efficacy of COX-2 inhibitor against neuropathic pain is still unclear. In this study, we investigated
Autor:
Nicole Avena, George C. Wagner, Hans Fisher, Alycia K. Halladay, Toshikatsu Nakashima, Taizo Kita
Publikováno v:
Neuropharmacology. 46:700-708
The behavioral and neurochemical effects of high doses of amphetamine administered to BALB/c mice were examined in the presence and absence of co-administered haloperidol (a D2 antagonist), SCH 23390 (a D1 antagonist) and risperidone (a mixed 5-HT2/D
Autor:
Masahiko Kawaguchi, Hitoshi Furuya, Noboru Konishi, Keiji Shimada, Masahiro Takahashi, Toshikatsu Nakashima
Publikováno v:
Neuroscience Letters. 356:37-40
To clarify the role of cyclooxygenase in the peripheral nerve on the development of neuropathic pain, we investigated the effects of peri-sciatic administration of indomethacin on the development of allodynia in a model of L5 single spinal nerve inju
Autor:
Toshiaki Nakatani, Taizo Kita, Kaoru Kubo, Itaru Narushima, Takeshi Tanaka, Toshikatsu Nakashima
Publikováno v:
Pharmacology & Toxicology. 92:125-130
To evaluate the relationship between nicotine and immunological inflammation, we investigated the effects of nicotine on plasma extravasation of the passive skin Arthus reaction, elicitated 4 hr after sensitizing skin with antiserum, and serum cortic
Autor:
Yohichi Ogawa, Toshiaki Yamanaka, Shino Inoue, Taizo Kita, Hiroshi Hosoi, Toshikatsu Nakashima
Publikováno v:
Neuroscience Letters. 323:234-238
The function of the 5-hydroxytryptamine (5-HT) system in the medial vestibular nucleus (MVN) was evaluated using KCl-evoked 5-HT release assessed by in vivo microdialysis. The release of 5-HT in the MVN was increased by the local application of KCl (