Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Toshiji Kanayama"'
Publikováno v:
Endocrine. 30:113-120
Chronic topical treatment of rats with a new RARgamma-selective retinoid, ER36009, resulted in a significant reduction of epididymal white adipose tissue and a significant increase of interscapular brown adipose tissue without affecting food intake.
Autor:
Taro Uchiyama, Tetsunori Matsumoto, Yoshiharu Suzuki, Toshiji Kanayama, Takeo Obara, Masami Ishida
Publikováno v:
Biological and Pharmaceutical Bulletin. 27:1907-1912
The effects of endogenous hyaluronan on cervical ripening during pregnancy were examined in rabbits. Hyaluronan of approximately 620 kilodalton (kDa) was detected in the uterine cervix on the 25th and 29th days of pregnancy, while it was not detected
Publikováno v:
Biochemical Pharmacology. 62:335-340
The action and the effect of the newly synthesized compounds 4GBE43 [ N -(1,2-diethyltetrahydro-1 H -pyrazol-4-yl)-4-[(2 E )-3,7-diethyl-2,6-octadienyl] oxybenzamide] and 2BBE43 [2-(benzyloxy)- N -(1,2-diethyltetrahydro-1 H -pyrazol-4-yl)benzamide] a
Publikováno v:
British Journal of Ophthalmology. 83:609-612
BACKGROUND/AIMS The biochemical basis for the development of subepithelial opacity of the cornea after excimer laser keratectomy has yet to be fully defined. The aim of this study was to evaluate the alterations of glycosaminoglycans (GAGs) after exc
Autor:
Toshiji Kanayama, Tomohiro Sakuta
Publikováno v:
International journal of dermatology. 45(11)
Background Photoaging (premature skin aging) results largely from repeated exposure of the skin to ultraviolet (UV) radiation from the sun. Topical all-trans retinoic acid (RA), the only agent that has been approved for the treatment of photoaging, h
Autor:
Tomohiro, Sakuta, Toshiji, Kanayama
Publikováno v:
European journal of dermatology : EJD. 15(6)
In addition to natural retinoids, new synthetic retinoids, such as adapalene and tazarotene, are currently available for the treatment of acne. In this study, we evaluated the comedolytic effect of a novel retinoic acid receptor (RAR)-gamma specific
Publikováno v:
Biochemical and biophysical research communications. 327(3)
We examined the expression pattern of hyaluronan synthase (HAS) mRNAs in the uterine cervix of pregnant mice. The expression levels of HAS-1 and -2 mRNAs peaked at delivery, whereas that of HAS-3 mRNA peaked on the 15th day of pregnancy. The regulati
Publikováno v:
Clinical biomechanics (Bristol, Avon). 14(5)
Objective. To assess the molecular weight dependence of the lubricating characteristics of additive hyaluronic acid in animal joints with experimental deterioration. Design. An experimental study in rabbits stifles in vitro. Background. Hyaluronic ac
Publikováno v:
Japanese Journal of Ophthalmology. 46:597-598
PURPOSE To investigate the effect of sodium hyaluronate molecular weight on corneal endothelial cells and intraocular pressure after penetrating keratoplasty in rabbits. MATERIAL AND METHOD Rotating autokeratoplasty was carried out on rabbits using s
Publikováno v:
Journal of cardiovascular pharmacology. 20(4)
The potential therapeutic value of a new prostacyclin analogue, (4z, 16s)-4,5,18,18,19,19-hexadehydro-16,20-dimethyl-delta 6(9a)- 9-(O)-methano-PGI1 (KP-10614), was studied in acute myocardial infarction in rats. Myocardial infarction was induced by