Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Toshihito, Isono"'
Autor:
Kridtapat Sirisereephap, Hikaru Tamura, Jong-Hyung Lim, Meircurius Dwi Condro Surboyo, Toshihito Isono, Takumi Hiyoshi, Andrea L. Rosenkranz, Yurie Sato-Yamada, Hisanori Domon, Akari Ikeda, Tomoyasu Hirose, Toshiaki Sunazuka, Nagako Yoshiba, Hiroyuki Okada, Yutaka Terao, Takeyasu Maeda, Koichi Tabeta, Triantafyllos Chavakis, George Hajishengallis, Tomoki Maekawa
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108798- (2024)
Summary: Aging is associated with increased susceptibility to chronic inflammatory bone loss disorders, such as periodontitis, in large part due to the impaired regenerative potential of aging tissues. DEL-1 exerts osteogenic activity and promotes bo
Externí odkaz:
https://doaj.org/article/b4d1b2b7ec0e4334957f28a8a3880467
Autor:
Fumio Takizawa, Hisanori Domon, Satoru Hirayama, Toshihito Isono, Karin Sasagawa, Daisuke Yonezawa, Akiomi Ushida, Satomi Tsutsuura, Tomohiro Miyoshi, Hitomi Mimuro, Akihiro Yoshida, Koichi Tabeta, Yutaka Terao
Publikováno v:
PLoS ONE, Vol 19, Iss 7 (2024)
Externí odkaz:
https://doaj.org/article/aabec1a53eb649bb89e7daf679b35634
Autor:
Hisanori Domon, Satoru Hirayama, Toshihito Isono, Karin Sasagawa, Fumio Takizawa, Tomoki Maekawa, Katsunori Yanagihara, Yutaka Terao
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Over the past 2 decades, the prevalence of macrolide-resistant Streptococcus pneumoniae (MRSP) has increased considerably, due to widespread macrolide use. Although macrolide usage has been proposed to be associated with treatment failure in
Externí odkaz:
https://doaj.org/article/976d14813a364dcea648d3ffca5d044d
Autor:
Yoshihito Yasui, Satoru Hirayama, Takumi Hiyoshi, Toshihito Isono, Hisanori Domon, Tomoki Maekawa, Koichi Tabeta, Yutaka Terao
Publikováno v:
Microorganisms, Vol 11, Iss 12, p 2969 (2023)
Streptococcus pneumoniae causes otitis media, sinusitis, and serious diseases such as pneumonia and bacteremia. However, the in vivo dynamics of S. pneumoniae infections and disease severity are not fully understood. In this study, we investigated pn
Externí odkaz:
https://doaj.org/article/188916d16dc5469192031a3db61a9578
Autor:
Satoru Hirayama, Hisanori Domon, Takumi Hiyoshi, Toshihito Isono, Hikaru Tamura, Karin Sasagawa, Fumio Takizawa, Yutaka Terao
Publikováno v:
FEBS Open Bio, Vol 12, Iss 6, Pp 1206-1219 (2022)
Recruitment of plasminogen is an important infection strategy of the human pathogen Streptococcus pneumoniae to invade host tissues. In Streptococcus aureus, triosephosphate isomerase (TPI) has been reported to bind plasminogen. In this study, the TP
Externí odkaz:
https://doaj.org/article/d2c6b326ad8449e1991dd77f90e16170
Autor:
Takumi Hiyoshi, Hisanori Domon, Tomoki Maekawa, Hikaru Tamura, Toshihito Isono, Satoru Hirayama, Karin Sasagawa, Fumio Takizawa, Koichi Tabeta, Yutaka Terao
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Neutrophil elastase (NE) functions as a host defense factor; however, excessive NE activity can potentially destroy human tissues. Although NE activity is positively correlated to gingival crevicular fluid and clinical attachment loss in per
Externí odkaz:
https://doaj.org/article/cc6db9cf5dbd4ab4b12296ed372d3f3e
Autor:
Hisanori Domon, Tomoki Maekawa, Toshihito Isono, Kazuyuki Furuta, Chikara Kaito, Yutaka Terao
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Bacterial and viral respiratory infections can initiate acute lung injury and acute respiratory distress syndrome. Neutrophils and their granule enzymes, including neutrophil elastase, are key mediators of the pathophysiology of acute respir
Externí odkaz:
https://doaj.org/article/9e061a8128da47aa84b0502e11573205
Autor:
Hikaru Tamura, Tomoki Maekawa, Hisanori Domon, Kridtapat Sirisereephap, Toshihito Isono, Satoru Hirayama, Takumi Hiyoshi, Karin Sasagawa, Fumio Takizawa, Takeyasu Maeda, Yutaka Terao, Koichi Tabeta
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 303 (2023)
The macrolide erythromycin (ERM) inhibits excessive neutrophil accumulation and bone resorption in inflammatory tissues. We previously reported that the expression of developmental endothelial locus-1 (DEL-1), an endogenous anti-inflammatory factor i
Externí odkaz:
https://doaj.org/article/eb3da03291af4e20b0ae1cb1bcca8b3e
Autor:
Hisanori Domon, Toshihito Isono, Takumi Hiyoshi, Hikaru Tamura, Karin Sasagawa, Tomoki Maekawa, Satoru Hirayama, Katsunori Yanagihara, Yutaka Terao
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 2 (2021)
ABSTRACT Streptococcus pneumoniae, the most common cause of community-acquired pneumonia, causes severe invasive infections, including meningitis and bacteremia. The widespread use of macrolides has been reported to increase the prevalence of macroli
Externí odkaz:
https://doaj.org/article/aa09be56f725467b82dafad69c1e15f0
Autor:
Toshihito Isono, Hisanori Domon, Kosuke Nagai, Tomoki Maekawa, Hikaru Tamura, Takumi Hiyoshi, Katsunori Yanagihara, Eiji Kunitomo, Shoji Takenaka, Yuichiro Noiri, Yutaka Terao
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240329 (2020)
Streptococcus pneumoniae is often isolated from patients with community-acquired pneumonia. Antibiotics are the primary line of treatment for pneumococcal pneumonia; however, rising antimicrobial resistance is becoming more prevalent. Hinokitiol, whi
Externí odkaz:
https://doaj.org/article/5797dd3ae5d442799818bae250be4648