Výsledky vyhledávání - "Toshihisa Maekawa"

Preclinical Study of Tacrolimus Ointment for Prevention of Its Systemic Absorption in Atopic Dermatitis Model Mice According to Their Skin Conditions

Autor: Wataru Uchida, Ryotaro Miki, Osamu Hosoya, Toshihisa Maekawa, Yutaro Hazama, Toshinobu Seki, Yuya Egawa, Shinji Oshima

Publikováno v: Japanese Journal of Pharmaceutical Health Care and Sciences

Tacrolimus (TL) is used topically for atopic dermatitis (AD) treatment. In AD, the skin shows various physiological alterations across individuals, body sites, and time-courses. Our previous study using rats showed that alterations in the skin barrie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cbe2799cca31d8d5084629d95b49756
https://doi.org/10.5649/jjphcs.43.477

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Effect of Physiological Changes in the Skin on Systemic Absorption of Tacrolimus Following Topical Application in Rats

Autor: Toshihisa Maekawa, Kazuhiro Morimoto, Ryotaro Miki, Yutaro Hazama, Toshinobu Seki, Shinji Oshima, Yuya Egawa

Publikováno v: Scopus-Elsevier

Tacrolimus (TL) ointment is a topical treatment for atopic dermatitis, a disease that exhibits various skin conditions. The effect of skin pathologies on the systemic absorption of TL and related side effects remains unknown. This study aimed to inve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf4879eee5dd01185146b4a95de09f9b
https://doi.org/10.1248/bpb.b15-00727

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