Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Toshihisa, Kawai"'
Autor:
Alexander Bontempo, Alexandra Chirino, Alireza Heidari, Alexandra Lugo, Satoru Shindo, Maria R. Pastore, Riccardo Madonia, Sibel A. Antonson, Cristina Godoy, Frank C. Nichols, Jan Potempa, Mary Ellen Davey, Toshihisa Kawai, Mark J. Cayabyab
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 10 (2024)
ABSTRACT The COVID-19 pandemic persists despite the availability of vaccines, and it is, therefore, crucial to develop new therapeutic and preventive approaches. In this study, we investigated the potential role of oral microbiome in SARS-CoV-2 infec
Externí odkaz:
https://doaj.org/article/ca9be7f51c8d413ea79582e6281a76ce
Autor:
Sharlene Demehri, Saynur Vardar, Cristina Godoy, Jose V. Lopez, Paisley Samuel, Toshihisa Kawai, Andrew T. Ozga
Publikováno v:
Microorganisms, Vol 12, Iss 9, p 1921 (2024)
Trillions of microbes comprise the human oral cavity, collectively acting as another bodily organ. Although research is several decades into the field, there is no consensus on how oral microbiomes differ in underrepresented groups such as Hispanic,
Externí odkaz:
https://doaj.org/article/ee44797c9bb24d24a06cabd280ea3849
Autor:
Shohei Yamashita, Motoki Okamoto, Melanie Mendonca, Natsumi Fujiwara, Eiko Kitamura, Chang-Sheng Sam Chang, Susanne Brueckner, Satoru Shindo, Nanako Kuriki, Marion A. Cooley, Navi Gill Dhillon, Toshihisa Kawai, John D. Bartlett, Eric T. Everett, Maiko Suzuki
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9600 (2024)
Excessive fluoride ingestion during tooth development can cause dental fluorosis. Previously, we reported that fluoride activates histone acetyltransferase (HAT) to acetylate p53, promoting fluoride toxicity in mouse ameloblast-like LS8 cells. Howeve
Externí odkaz:
https://doaj.org/article/ef5a752d2cde443ab9db243d520b0a3f
Autor:
Janaki Chandra, Shin Nakamura, Satoru Shindo, Elizabeth Leon, Maria Castellon, Maria Rita Pastore, Alireza Heidari, Lukasz Witek, Paulo G. Coelho, Toshiyuki Nakatsuka, Toshihisa Kawai
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1835 (2024)
Surface pre-reacted glass-ionomer (S-PRG) is a new bioactive filler utilized for the restoration of decayed teeth by its ability to release six bioactive ions that prevent the adhesion of dental plaque to the tooth surface. Since ionic liquids are re
Externí odkaz:
https://doaj.org/article/cfa0c8411e4444649d849a009e716997
Autor:
Kenta Yamamoto, Shin-Ichi Sawada, Satoru Shindo, Shin Nakamura, Young M. Kwon, Nazanin Kianinejad, Saynur Vardar, Maria Hernandez, Kazunari Akiyoshi, Toshihisa Kawai
Publikováno v:
Gels, Vol 10, Iss 6, p 377 (2024)
Osteoclast stimulatory transmembrane protein (OC-STAMP) plays a pivotal role in the promotion of cell fusion during osteoclast differentiation (osteoclastogenesis) in the context of pathogenic bone resorption. Thus, it is plausible that the suppressi
Externí odkaz:
https://doaj.org/article/c641e1ddfb294b369c85bdaeb6f10516
Autor:
Shengyuan Huang, Guoqin Cao, Dong Dai, Qiuping Xu, Sunniva Ruiz, Satoru Shindo, Shin Nakamura, Toshihisa Kawai, Jiang Lin, Xiaozhe Han
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Diabetic retinopathy (DR) is one of the leading causes of blindness. Periodontitis is one of the highest oral incidences and has been closely related to various systemic conditions through Porphyromonas gingivalis (P. gingivalis). P. gingivalis OMVs,
Externí odkaz:
https://doaj.org/article/b8ee002ef36247cb90958d55c13c0657
Autor:
Giuseppe Pezzotti, Tetsuya Adachi, Hayata Imamura, Davide Redolfi Bristol, Keiji Adachi, Toshiro Yamamoto, Narisato Kanamura, Elia Marin, Wenliang Zhu, Toshihisa Kawai, Osam Mazda, Toru Kariu, Tomonori Waku, Frank C. Nichols, Pietro Riello, Flavio Rizzolio, Tania Limongi, Kazu Okuma
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13351 (2023)
The aim of this study was to elucidate the chemistry of cellular degeneration in human neuroblastoma cells upon exposure to outer-membrane vesicles (OMVs) produced by Porphyromonas gingivalis (Pg) oral bacteria by monitoring their metabolomic evoluti
Externí odkaz:
https://doaj.org/article/d3cefbd980d6476ab931588fa1c36d9a
Publikováno v:
Biology, Vol 12, Iss 7, p 976 (2023)
The immune system plays an important role in the skeletal system during bone repair and regeneration. The controlled release of biological factors from the immune system could facilitate and optimize the bone remodeling process through the regulation
Externí odkaz:
https://doaj.org/article/39f38256cad2469abca3cea8603fa855
Autor:
Satoru Shindo, Roodelyne Pierrelus, Atsushi Ikeda, Shin Nakamura, Alireza Heidari, Maria Rita Pastore, Elizabeth Leon, Sunniva Ruiz, Harsh Chheda, Rhea Khatiwala, Tomoki Kumagai, George Tolson, Islam Elderbashy, Kazuhisa Ouhara, Xiaozhe Han, Maria Hernandez, Saynur Vardar-Sengul, Hideki Shiba, Toshihisa Kawai
Publikováno v:
Cells, Vol 12, Iss 8, p 1109 (2023)
Elevated osteoclast (OC)-mediated bone resorption, a common pathological feature between periodontitis and rheumatoid arthritis (RA), implicates a possible mutually shared pathogenesis. The autoantibody to citrullinated vimentin (CV), a representativ
Externí odkaz:
https://doaj.org/article/3d850b305bea4815b3b3f71e2b316641
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6693 (2023)
Immune cell pattern-recognition receptors such as Toll-like receptors (TLRs) play important roles in the regulation of host responses to periodontal pathogens. Our previous studies have demonstrated that immune regulatory B cells were activated by TL
Externí odkaz:
https://doaj.org/article/d8f2f2affe174affa5dd3149c22257d8