Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Toshihiro Umehara"'
Autor:
Takayoshi Sasako, Toshihiro Umehara, Kotaro Soeda, Kazuma Kaneko, Miho Suzuki, Naoki Kobayashi, Yukiko Okazaki, Miwa Tamura-Nakano, Tomoki Chiba, Domenico Accili, C. Ronald Kahn, Tetsuo Noda, Hiroshi Asahara, Toshimasa Yamauchi, Takashi Kadowaki, Kohjiro Ueki
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Sasako et al. show that disruption of the insulin/IGF-1 signaling by suppressing Akt activity in mouse skeletal muscle can accelerate osteosarcopenia and shortens lifespan, which is reversed by inactivation of FoxOs rather than activation of mTOR, su
Externí odkaz:
https://doaj.org/article/485f04e2a5324e6780b6abc02a8a35ba
Autor:
Toshihiro Umehara
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0197900 (2018)
BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) has been reported to have a negative effect on bone mineral density (BMD) in Asian populations. Whether such an association exists in Western populations is less clear. METHODS:This cross-sectional
Externí odkaz:
https://doaj.org/article/d8cef0a1667f441faa89ee4c8d64715a
Autor:
Toshihiro Umehara
Publikováno v:
Journal of Open Source Software. 6:3166
Data processing and data cleaning are essential steps before applying statistical or machine learning procedures. R provides a flexible way for data processing using vectors. R packages also provide other ways for manipulating data such as using SQL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e4e822572ca375df5101fce80b8bb29
https://doi.org/10.21105/joss.03166
https://doi.org/10.21105/joss.03166
Autor:
Tatsuhiko Kodama, Toshihiro Umehara, Kazuyuki Tobe, Aya Iwane, Takashi Kadowaki, Takao Hamakubo, Takayoshi Sasako, Yukiko Okazaki, Naoki Kobayashi, Hironori Waki, Mitsuru Ohsugi, Naoto Kubota, Masatoshi Kobayashi, Motoharu Awazawa, Seiichiro Aoe, Ryo Suzuki, Kohjiro Ueki, Keiko Horiuchi
Publikováno v:
Molecular and Cellular Biology
Adipocyte differentiation is regulated by various mechanisms, of which mitotic clonal expansion (MCE) is a key step. Although this process is known to be regulated by cell cycle modulators, the precise mechanism remains unclear.
Adipocyte differ
Adipocyte differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcaca2c2b52f4b1616f7f53083f56089
https://pubmed.ncbi.nlm.nih.gov/29866655
https://pubmed.ncbi.nlm.nih.gov/29866655
Autor:
Toshihiro Umehara
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0197900 (2018)
Background Nonalcoholic fatty liver disease (NAFLD) has been reported to have a negative effect on bone mineral density (BMD) in Asian populations. Whether such an association exists in Western populations is less clear. Methods This cross-sectional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d978c77efbe6ef801a9723f0a3e0f516
https://pubmed.ncbi.nlm.nih.gov/29897928
https://pubmed.ncbi.nlm.nih.gov/29897928
Autor:
Houda, Sellami-Mnif, Toshihiro, Umehara, Yuriko, Yamazaki, Hiroyuki, Otake, Reie, Matoba, Anna, Sakashita, Masafumi, Matsuda
Publikováno v:
Diabetology International; Jan2020, Vol. 11 Issue 1, p49-56, 8p
Autor:
Naoki Shinyashiki, Megumi Asano, Satoru Naito, Maysayuki Tokita, Hidenori Miyairi, Masami Shiotsubo, Gaku Yamada, Yoshihito Hayashi, Toshihiro Umehara, Tohru Nagahama, Satoru Mashimo, Nobuhiro Miura, Shin Yagihara
Publikováno v:
Subsurface Sensing Technologies and Applications. 2:15-30
Microwave dielectric measurements were performed in the frequency range from 1 mHz up to 30 GHz using a time domain reflectometry (TDR) method for emulsions and gels. Flat-end sample cells have been used in the TDR measurement to contact a small spot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::913b214e92affc8177b0ccf98f76c937
https://doi.org/10.1023/a:1010162025428
https://doi.org/10.1023/a:1010162025428
Publikováno v:
Esophagus. 6:259-261
We report a case of a fistula caused by cervical anastomotic leakage after pharyngo-laryngo-esophagectomy that was successfully and safely treated with a self-expandable covered stent. A patient with esophageal carcinoma and inferior pharyngeal carci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::578f4645987c0d192a31b36b4bcc0352
https://doi.org/10.1007/s10388-009-0207-y
https://doi.org/10.1007/s10388-009-0207-y
Autor:
Masatoshi Kobayashi, Mitsuru Ohsugi, Takayoshi Sasako, Motoharu Awazawa, Toshihiro Umehara, Aya Iwane, Naoki Kobayashi, Yukiko Okazaki, Naoto Kubota, Ryo Suzuki, Hironori Waki, Keiko Horiuchi, Takao Hamakubo, Tatsuhiko Kodama, Seiichiro Aoe, Kazuyuki Tobe, Takashi Kadowaki, Kohjiro Ueki
Publikováno v:
Molecular & Cellular Biology; Aug2018, Vol. 38 Issue 16, p1-25, 25p
Publikováno v:
The Journal of Chemical Physics. 102:9474-9479
The hydration structure of L‐xylo and D‐arabo ascorbic acids in aqueous solutions were investigated by a dielectric relaxation measurement over a wide frequency range from 10 MHz to 10 GHz from a standpoint on the difference of biological activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1f288c6813dfb3dac4deb555bdf2b71
https://doi.org/10.1063/1.468816
https://doi.org/10.1063/1.468816