Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Toshihiro U"'
Autor:
Masaru Tani, Koji Hatano, Akihiro Yoshimura, Yuki Horibe, Yutong Liu, Nesrine Sassi, Toshiki Oka, Yohei Okuda, Akinaru Yamamoto, Toshihiro Uemura, Gaku Yamamichi, Yu Ishizuya, Yoshiyuki Yamamoto, Taigo Kato, Atsunari Kawashima, Norio Nonomura
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Bone-modifying agents (BMA) are extensively used in treating patients with prostate cancer with bone metastases. However, this increases the risk of medication-related osteonecrosis of the jaw (MRONJ). The safety of long-term BMA administrat
Externí odkaz:
https://doaj.org/article/fc2b4f95788741b2a0b97445519c779c
Autor:
Tomohide Yoshie, Toshihiro Ueda, Yasuhiro Hasegawa, Masataka Takeuchi, Masafumi Morimoto, Yoshifumi Tsuboi, Ryoo Yamamoto, Shogo Kaku, Junichi Ayabe, Takekazu Akiyama, Daisuke Yamamoto, Kentaro Mori, Hiroshi Kagami, Hidemichi Ito, Hidetaka Onodera, Yasuyuki Kaga, Haruki Ohtsubo, Kentaro Tatsuno, Noriko Usuki, Satoshi Takaishi, Yoshihisa Yamano
Publikováno v:
Stroke: Vascular and Interventional Neurology, Vol 4, Iss 5 (2024)
Background The benefits of endovascular thrombectomy (EVT) for distal medium vessel occlusions (DMVOs) are not well established. This study aimed to determine the superiority of EVT over intravenous tissue‐type plasminogen activator (IV tPA) in the
Externí odkaz:
https://doaj.org/article/89199ac6480541ad843bbb66e14d30c8
Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101717- (2024)
Bacteria in the oral microbiome are poorly identified owing to the lack of established culture methods for them. Thus, this study aimed to use culture-free analysis techniques, including bacterial single-cell genome sequencing, to identify bacterial
Externí odkaz:
https://doaj.org/article/ccfee7d359ce4bba8c0abc3723900afb
Autor:
Kazutaka UCHIDA, Nobuyuki SAKAI, Hiroshi YAMAGAMI, Kohei UEMURA, Hirotoshi IMAMURA, Masataka TAKEUCHI, Manabu SHIRAKAWA, Fumihiro SAKAKIBARA, Koichi HARAGUCHI, Naoto KIMURA, Kentaro SUZUKI, Junichi AYABE, Daisuke YAMAMOTO, Seigo SHINDO, Atsushi KIMOTO, Kenichi MORITA, Yoshinori AKIYAMA, Hidesato TAKEZAWA, Shingo TOYOTA, Kanta TANAKA, Shigen KASAKURA, Eisuke TSUKAGOSHI, Toshihiro UEDA, Shinichi YOSHIMURA, Japan Trevo Registry Investigators
Publikováno v:
Neurologia Medico-Chirurgica, Vol 63, Iss 11, Pp 503-511 (2023)
Endovascular therapy (EVT) for real-world patients after extended time frames is associated with concerns about its efficacy and safety. We conducted a prospective registry at 77 centers between November 2019 and October 2020. The registry criteria i
Externí odkaz:
https://doaj.org/article/f78de34a2937465983b74792e408ab2e
Autor:
Emiko Tanaka Isomura, Shinichiro Suna, Hiroyuki Kurakami, Shungo Hikoso, Toshihiro Uchihashi, Yusuke Yokota, Yasushi Sakata, Susumu Tanaka
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract In this study, we investigated whether toothbrushing timing affects cardiovascular disease risk. We enrolled 1675 patients aged ≥ 20 years who were hospitalized for surgery, examination, or medical treatment. The participants were categori
Externí odkaz:
https://doaj.org/article/2bd846e3e44e4e9d8424d35397d2fed1
Autor:
Toshihiro Ueda, Satoshi Takaishi, Tomohide Yoshie, Noriko Usuki, Kentaro Tatsuno, Haruki Ohtsubo, Takashi Araga, Yasuyuki Kaga, Tatsuro Takada
Publikováno v:
BMC Neurology, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background The optimal treatment for intracranial artery stenosis (ICAS) has not been established. We retrospectively examined the initial and long-term outcomes associated with restenosis of a combination therapy of balloon angioplasty and
Externí odkaz:
https://doaj.org/article/7123e0bc67b44cf1b405ec177a5475d9
Autor:
Takayoshi Sasako, Toshihiro Umehara, Kotaro Soeda, Kazuma Kaneko, Miho Suzuki, Naoki Kobayashi, Yukiko Okazaki, Miwa Tamura-Nakano, Tomoki Chiba, Domenico Accili, C. Ronald Kahn, Tetsuo Noda, Hiroshi Asahara, Toshimasa Yamauchi, Takashi Kadowaki, Kohjiro Ueki
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Sasako et al. show that disruption of the insulin/IGF-1 signaling by suppressing Akt activity in mouse skeletal muscle can accelerate osteosarcopenia and shortens lifespan, which is reversed by inactivation of FoxOs rather than activation of mTOR, su
Externí odkaz:
https://doaj.org/article/485f04e2a5324e6780b6abc02a8a35ba
Autor:
Toshihiro Uemura, Atsunari Kawashima, Kentaro Jingushi, Daisuke Motooka, Takuro Saito, Sassi Nesrine, Toshiki Oka, Yohei Okuda, Akinaru Yamamoto, Gaku Yamamichi, Eisuke Tomiyama, Yu Ishizuya, Yoshiyuki Yamamoto, Taigo Kato, Koji Hatano, Kazutake Tsujikawa, Hisashi Wada, Norio Nonomura
Publikováno v:
Heliyon, Vol 9, Iss 9, Pp e19800- (2023)
This is the first study to determine the clinical importance of circulating bacterial DNA in patients with renal cell carcinoma (RCC). We performed 16S rRNA metagenomic analysis of serum extracellular vesicles (EVs) from 88 patients with RCC and 10 h
Externí odkaz:
https://doaj.org/article/773d78540e4440d9b22b02288d314b51
Autor:
Emi Fujibayashi, Satomi Mukai, Kosuke Torigata, Yumi Ando, Toshihiro Uchihashi, Masami Nozaki, Susumu Tanaka, Masato Okada, Mikihiko Kogo, Hiroshi Nojima, Norikazu Yabuta
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract The epithelial-to-mesenchymal transition (EMT) is a critical process by which cancer cells acquire malignant features. However, the molecular mechanism and functional implications of EMT and the mesenchymal-to-epithelial transition (MET) in
Externí odkaz:
https://doaj.org/article/48e63075d1b2460fa119cc1239c057f1
Autor:
Yoshiyuki Yamamoto, MD, PhD, Atsunari Kawashima, MD, PhD, Toshitaka Morishima, MD, PhD, Toshihiro Uemura, MD, Akinaru Yamamoto, MD, Gaku Yamamichi, MD, Eisuke Tomiyama, MD, Makoto Matsushita, MD, PhD, Taigo Kato, MD, PhD, Koji Hatano, MD, PhD, Isao Miyashiro, MD, PhD, Norio Nonomura, MD, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 8, Iss 3, Pp 101157- (2023)
Purpose: Radical cystectomy (RC) with neoadjuvant chemotherapy is the most commonly recommended treatment for muscle-invasive bladder cancer (MIBC), yet RC with urinary diversion remains an invasive treatment. Although some patients with MIBC gain go
Externí odkaz:
https://doaj.org/article/68cb5efd97ce497ab7e4c579e823a93a