Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Toshihiro Tomii"'
Autor:
Azusa Mayumi, Toshihiro Tomii, Takuyo Kanayama, Takashi Mikami, Kuniaki Tanaka, Hiroo Ueno, Hideki Yoshida, Itaru Kato, Machiko Kawamura, Tatsutoshi Nakahata, Junko Takita, Hajime Hosoi, Toshihiko Imamura
Publikováno v:
Cancer Gene Therapy. 29:1930-1938
JAK2 rearrangements can occur in Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL). Here, we performed functional analysis of the SPAG9::JAK2 fusion, which was identified in a pediatric patient with Ph-like ALL, to establish mol
Autor:
Nobutaka Kiyokawa, Takashi Mikami, Keizo Horibe, Tatsutoshi Nakahata, Makiko Morita, Mio Yano, Itaru Kato, Souichi Adachi, Junko Takita, Hajime Hosoi, Kuniaki Tanaka, Toshihiro Tomii, Kenichi Sakamoto, Azusa Mayumi, Toshihiko Imamura, Emi Soma
Publikováno v:
Leukemia. 35:2092-2096
Autor:
Masashi Sanada, Hiroaki Goto, Junko Takita, Hajime Hosoi, Shotaro Iwamoto, Mio Yano, Daisuke Asai, Takeshi Inukai, Masayoshi Minegishi, Chihiro Tomoyasu, Toshihiro Tomii, Akira Shimada, Toshihiko Imamura, Kanji Sugita
Publikováno v:
International Journal of Hematology. 108:312-318
In this study, we performed genetic analysis of 83 B cell precursor acute lymphoblastic leukemia (B-ALL) cell lines. First, we performed multiplex ligation-dependent probe amplification analysis to identify copy number abnormalities (CNAs) in eight g
Autor:
Hideki Yoshida, Takuyo Kanayama, Azusa Mayumi, Tatsutoshi Nakahata, Toshihiko Imamura, Junko Takita, Takashi Mikami, Toshihiro Tomii, Machiko Kawamura, Hajime Hosoi, Kuniaki Tanaka, Itaru Kato
Publikováno v:
Blood. 138:4326-4326
[Background and aim of this study] Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is a distinct subtype of B-ALL with poor prognosis. JAK2 related fusion genes have been identified in this subtype, especially in adolescent an
Autor:
Shinichi Tamura, Hajime Hosoi, Junko Do, Hiroyuki Ishida, Hiroshi Kuroda, Mari Gen, Miki Kobayashi, Toshihiko Imamura, Takayo Urata, Shinya Osone, Toshihiro Tomii
Publikováno v:
Journal of Pediatric Hematology/Oncology. 39:e394-e398
Although bone marrow failure in patients with dyskeratosis congenita (DKC) can be successfully treated with allogeneic hematopoietic cell transplantation (allo-HCT) using a reduced intensity conditioning (RIC) regimen, the outcome of nonhematological
Development of acute lymphoblastic leukemia with IgH-EPOR in a patient with secondary erythrocytosis
Autor:
Kazutaka Takagi, Mio Yano, Seiji Tanaka, Tsutsumi Yasuhiko, Toshihiko Imamura, Toshihiro Tomii, Chihiro Tomoyasu, Hiroshi Komatsu, Nobuhiko Uoshima, Kenichi Sakamoto
Publikováno v:
International Journal of Hematology. 104:741-743
We report the first patient to develop ALL with a fusion gene of the erythropoietin receptor (EPOR) with immunoglobulin heavy chain (IgH) 22 years after a diagnosis of secondary erythrocytosis with unknown etiology. The IgH-EPOR rearrangement is know
Publikováno v:
Blood. 134:5044-5044
[Background and aim of this study] Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is a distinct subtype of B-ALL with poor prognosis. JAK2 related fusion genes with diverse partner genes have been identified in this subtype,
Autor:
Makiko Morita, Mio Yano, Kenichi Sakamoto, Junko Takita, Takashi Mikami, Toshihiro Tomii, Nobutaka Kiyokawa, Toshihiko Imamura, Souichi Adachi, Keizo Horibe, Hajime Hosoi, Kuniaki Tanaka, Itaru Kato
Publikováno v:
Blood. 132:1557-1557
[Background and aim of this study] Kinase fusion protein is putative therapeutic target of hematological malignancies. Previously, we identified NCOR1-LYN fusion gene in which NCOR1 exon 34 was fused in-frame to LYN exon 7 in a pediatric patient with
Publikováno v:
European Journal of Medical Genetics. 55:763-765