Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Toshihiro Sekimoto"'
Autor:
Yoon Sik Shin, Noriko Yasuhara, Young Han Won, Toshihiro Sekimoto, Hye Rim Hong, Il Yeong Park, Jinsue Song, Eiki Yamashita, Se-Young Son, Soo Jae Lee, Saehae Choi, Yoshihiro Yoneda
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 70:1050-1060
Snail contributes to the epithelial–mesenchymal transition by suppressing E-cadherin in transcription processes. The Snail C2H2-type zinc-finger (ZF) domain functions both as a nuclear localization signal which binds to importin β directly and as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f83ef071fa228e3ddb032cfef3c60248
https://doi.org/10.1107/s1399004714000972
https://doi.org/10.1107/s1399004714000972
Publikováno v:
Cell Structure and Function. 36:57-67
Many transport factors, such as importins and exportins, have been identified, and the molecular mechanisms underlying nucleocytoplasmic transport have been characterized. The specific molecules that are carried by each transport factor and the tempo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6399916b3ff22ff2edf41eb008412d
https://doi.org/10.1247/csf.10026
https://doi.org/10.1247/csf.10026
Autor:
Takashi Miki, Sadanori Watanabe, Toshihiro Sekimoto, Toshimasa Ishizaki, Shuh Narumiya, Yoshihiro Yoneda, Katsuya Okawa
Publikováno v:
Journal of Biological Chemistry. 284:5753-5762
Mammalian homolog of Drosophila diaphanous (mDia) consisting of three isoforms, mDia1, mDia2, and mDia3, is an effector of Rho GTPases that catalyzes actin nucleation and polymerization. Although the mDia actions on actin dynamics in the cytoplasm ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c2cdbcb9ee87f5e3e07558f0d7f2ee0
https://doi.org/10.1074/jbc.m806191200
https://doi.org/10.1074/jbc.m806191200
Autor:
Reiner Peters, Wei Yao, Yoshihiro Yoneda, Toshihiro Sekimoto, Gert Bange, Klemens Wild, Bettina Bradatsch, Jun Katahira, Ed Hurt, Irmi Sinning, Guido Boese, Viola Baumgärtel, Eva Kowalinski, Jochen Bassler
Publikováno v:
Molecular Cell. 27(5):767-779
Shuttling transport receptors carry cargo through nuclear pore complexes (NPCs) via transient interactions with Phe-Gly (FG)-rich nucleoporins. Here, we identify Arx1, a factor associated with a late 60S preribosomal particle in the nucleus, as an un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6b239845f37a2dfb45c54a958f09fd
Autor:
Kunio Shiota, Tohru Kimura, Yoshikazu Arai, Masahito Ikawa, Hisaaki Taniguchi, Yoshihiro Yoneda, Toshinobu Nakamura, Hiroki Umehara, Masaru Okabe, Satoshi Tanaka, Masaaki Masuhara, Toru Nakano, Toshihiro Sekimoto
Publikováno v:
Nature Cell Biology. 9:64-71
DNA methylation is an important means of epigenetic gene regulation and must be carefully controlled as a prerequisite for normal early embryogenesis. Although global demethylation occurs soon after fertilization, it is not evenly distributed through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd5092c9db792e828f2efc48d495eb1
https://doi.org/10.1038/ncb1519
https://doi.org/10.1038/ncb1519
Autor:
Yukihiro Nagata, Hideki Yamasaki, Masayuki Ozawa, Tsutomu Douchi, Yoshihiro Yoneda, Tadashi Ohkubo, Toshihiro Sekimoto
Publikováno v:
Genes to Cells. 10:455-464
Snail, a DNA-binding zinc finger protein, functions as a transcriptional repressor for genes including E-cadherin during development and the acquisition of tumor cell invasiveness. Human Snail is a 264-amino acid nuclear protein with an amino-termina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1486471da9bd474f47aa22a63e436e4
https://doi.org/10.1111/j.1365-2443.2005.00850.x
https://doi.org/10.1111/j.1365-2443.2005.00850.x
Autor:
Atsushi Maruyama, Kenji Ogino, Yoshihiro Yoneda, Yoichi Miyamoto, Ryosuke Ushijima, Taro Tachibana, Arihiro Kano, Naoko Sakaguchi, Toshihiro Sekimoto
Publikováno v:
Biochemical and Biophysical Research Communications. 330(No. 3):880-886
The signal transducer and activator of transcription 3 (STAT3) is a transcription factor that is involved in a variety of biological functions. STAT3 is activated by cytokines and growth factors via the phosphorylation of a tyrosine residue, dimeriza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a92cb519363b380b75fc74fb471c3d
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100810367
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100810367
Publikováno v:
The EMBO Journal. 23:1934-1942
p27(Kip1) (p27), a CDK inhibitor, migrates into the nucleus, where it controls cyclin-CDK complex activity for proper cell cycle progression. We report here that the classical bipartite-type basic amino-acid cluster and the two downstream amino acids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa09f2f08e8b3e59a00a7f09845838a
https://doi.org/10.1038/sj.emboj.7600198
https://doi.org/10.1038/sj.emboj.7600198
Autor:
Masato Yoshimura, Tomitake Tsukihara, Hiroaki Sakai, Eiki Yamashita, Soo Jae Lee, Atsushi Nakagawa, Yoshihiro Yoneda, Emi Nagoshi, Naoko Imamoto, Khoon Tee Chong, Toshihiro Sekimoto
Publikováno v:
Science. 302:1571-1575
The sterol regulatory element–binding protein 2 (SREBP-2), a nuclear transcription factor that is essential for cholesterol metabolism, enters the nucleus through a direct interaction of its helix-loop-helix leucine zipper domain with importin-β.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baeeca62d4e62c55c7e463d4d4b66f1d
https://doi.org/10.1126/science.1088372
https://doi.org/10.1126/science.1088372
Publikováno v:
ACTA HISTOCHEMICA ET CYTOCHEMICA. 35:435-440
In eukaryotic cells, functional macromolecules such as protein and RNA traverse the nuclear envelope, thus permitting communication between the nucleus and the cytoplasm. The molecular mechanism of the nucleocytoplasmic transport has been extensively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17c2a28d5757ccd6464d4c79ebb9168b
https://doi.org/10.1267/ahc.35.435
https://doi.org/10.1267/ahc.35.435