Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Toshihiro Ohgawara"'
Autor:
Kazuki Nabeshima, Shiho Tanaka, Seiji Kondo, Katsumi Kobata, Jiro Kawashima, Toshihiro Ohgawara, Toshihiro Kikuta
Publikováno v:
Diagnostic Cytopathology
Pemphigus vulgaris (PV) is a chronic autoimmune bullous disease characterized by the formation of suprabasal cleavage and acantholysis. As this disease almost always affects the oral mucosa, conventional cytological smears of oral lesions can be used
Autor:
Nao Ikeda, Toshihiro Ohgawara, Takashi Nishida, Masaharu Takigawa, Kazumi Kawata, Takashi Yamashiro, Tarek Abd El Kader, Kumi Sumiyoshi, Satoshi Kubota, Tsuyoshi Shimo
Publikováno v:
Journal of Cellular Biochemistry. 114:2094-2100
Micro RNA (miRNA) is a small non-coding post-transcriptional RNA regulator that is involved in a variety of biological events. In order to specify the role of miRNAs in cartilage metabolism, we comparatively analyzed the expression profile of known m
Autor:
Masaharu Takigawa, Toshihiro Ohgawara, Makoto Suzuki, Akiko Suzuki, Teruko Takano-Yamamoto, Bernard Perbal, Kumiko Kohsaka, Kenji Hoshi, Toshiya Fujii, Takeyasu Maeda, Noureddine Lazar, Harumi Kawaki, Satoshi Kubota
Publikováno v:
Bone. 49:975-989
CCN family proteins play diverse roles in many aspects of cellular processes such as proliferation, differentiation, adhesion, migration, angiogenesis and survival. In the bone tissue of vertebrate species, the expression of most CCN family members h
Autor:
Naito Kurio, Mitsuhiro Hoshijima, Tarek Abd El Kader, Akira Sasaki, Tsuyoshi Shimo, Harumi Kawaki, Toshihiro Ohgawara, Bernard Perbal, Danilo Janune, Masaharu Takigawa, Satoshi Kubota
Publikováno v:
Journal of Cell Communication and Signaling. 5:291-299
The CCN family of proteins consists of six members with conserved structural features. These proteins play several roles in the physiology and pathology of cells. Among the pathological roles of the CCN family, one of the most important and controver
Regulation of chondrocytic phenotype by micro RNA 18a: Involvement ofCcn2/Ctgfas a major target gene
Autor:
Toshihiro Ohgawara, Harumi Kawaki, Naito Kurio, Masaharu Takigawa, Akira Sasaki, Satoshi Kubota, Eriko Aoyama, Takanori Eguchi, Seiji Kondo
Publikováno v:
FEBS Letters. 583:1006-1010
We searched for miRNAs that were down-regulated in chondrocytic cells and predicted to target CCN2/connective tissue growth factor (CCN2/CTGF) that promotes endochondral ossification. Among them, expression of miR-18a was most strongly repressed in c
Autor:
Harumi Kawaki, Bernard Perbal, Takeyasu Maeda, Karen M. Lyons, Akiko Suzuki, Satoshi Kubota, Toshihiro Ohgawara, Noureddine Lazar, Tomohiro Yamada, Masaharu Takigawa, Tatsushi Matsumura
Publikováno v:
Journal of Bone and Mineral Research. 23:1751-1764
CCN2 is best known as a promoter of chondrocyte differentiation among the CCN family members, and its null mice display skeletal dysmorphisms. However, little is known concerning roles of the other CCN members in chondrocytes. Using both in vivo and
Autor:
Akira Sasaki, Soichiro Ibaragi, Junji Uehara, Toshihiro Ohgawara, Takuo Kuboki, Yoshiki Mukudai, Satoshi Kubota, Masaharu Takigawa, Takanori Eguchi, Kazumi Kawata
Publikováno v:
Molecular and Cellular Biology. 28:2391-2413
Matrix metalloproteinase 3 (MMP3) is well known as a secretory endopeptidase that degrades extracellular matrices. Recent reports indicated the presence of MMPs in the nucleus (A. J. Kwon et al., FASEB J. 18:690-692, 2004); however, its function has
Autor:
Kumi, Sumiyoshi, Satoshi, Kubota, Toshihiro, Ohgawara, Kazumi, Kawata, Tarek, Abd El Kader, Takashi, Nishida, Nao, Ikeda, Tsuyoshi, Shimo, Takashi, Yamashiro, Masaharu, Takigawa
Publikováno v:
Journal of cellular biochemistry. 114(9)
Micro RNA (miRNA) is a small non-coding post-transcriptional RNA regulator that is involved in a variety of biological events. In order to specify the role of miRNAs in cartilage metabolism, we comparatively analyzed the expression profile of known m
Autor:
Takashi Nishida, Toshihiro Ohgawara, Kazumi Kawata, Masaharu Takigawa, Satoshi Kubota, Tsuyoshi Shimo, Takashi Yamashiro, Kumi Sumiyoshi
Publikováno v:
Biochemical and biophysical research communications. 402(2)
The process of endochondral ossification is strictly regulated by a variety of extracellular and intracellular factors. Recently, it has become recognized that specific miRNAs are involved in this process by regulating the expression of the relevant
Autor:
Satoshi Kubota, Tsuyoshi Shimo, Harumi Kawaki, Toshihiro Ohgawara, Yoshiki Mukudai, Seiji Kondo, Masaharu Takigawa, Kumi Sumiyoshi, Takanori Eguchi
Publikováno v:
CCN Proteins in Health and Disease ISBN: 9789048137787
CCN2/CTGF is a multifunctional molecule that has been shown to play a central role in chondrocyte differentiation. During this process, the expression of ccn2 is tightly regulated to confer a maximal level at prehypertrophic – hypertrophic stages,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee384d889d67df4171751beeda8a564b
https://doi.org/10.1007/978-90-481-3779-4_4
https://doi.org/10.1007/978-90-481-3779-4_4