Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Toshihiro Obayashi"'
Autor:
Takayuki Ozawa, Hideo Yamamoto, Makoto Katayama, Toshihiro Obayashi, Masashi Tanaka, Yuji Nimura
Publikováno v:
Biochemical and Biophysical Research Communications. 182:913-920
To understand the role of mitochondria in carcinogenesis, we compared the amount of deleted mtDNAs between human hepatic tumors and surrounding cirrhotic portion of the liver of ten patients by using polymerase chain reaction (PCR). Multiple mtDNA de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bcb3d88f7f718d5ab6533b7a6178cf0
https://doi.org/10.1016/0006-291x(92)91819-c
https://doi.org/10.1016/0006-291x(92)91819-c
Autor:
Junpei Asai, Toshihiro Obayashi, Tatsuo Satake, Makoto Nagano, Takayuki Ito, Yoshihiro Hanaki, Kazuki Hattori, Takayuki Ozawa, Masashi Tanaka, Satoru Sugiyama
Publikováno v:
American Heart Journal. 121:1735-1742
Cardiac function deteriorates with age, and endogenous damage to mitochondrial DNA (mt DNA) is believed to be a major contributory factor to aging. Mitochondria occupy a pivotal position in energy metabolism, and mitochondria have their own DNA, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4b577dd6dddbb4a7422d2da46c95b0
https://doi.org/10.1016/0002-8703(91)90020-i
https://doi.org/10.1016/0002-8703(91)90020-i
Autor:
Toshihiro, Obayashi, Takayuki, Ito
Publikováno v:
Nihon rinsho. Japanese journal of clinical medicine. 60
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b3d0ff04c6d7c3c129dabdd6ded733a2
https://pubmed.ncbi.nlm.nih.gov/12013935
https://pubmed.ncbi.nlm.nih.gov/12013935
Publikováno v:
Heart (British Cardiac Society). 79(1)
A 20 year old man with severe chest pain was hospitalised for acute myocardial infarction. Coronary angiography revealed total obstruction of his right coronary artery, which was successfully recanalised by direct percutaneous transluminal coronary a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee45ac96a100f4ef190a42e7483adc8
https://pubmed.ncbi.nlm.nih.gov/9505929
https://pubmed.ncbi.nlm.nih.gov/9505929
Autor:
Toshikatsu Ichihara, Kyo Adachi, Takayuki Ozawa, Yoshimune Hiruta, Masashi Tanaka, Mamoru Mochizuki, Keisho Chin, Toshihiro Obayashi, Kouzou Shitomi
Publikováno v:
Internal medicine (Tokyo, Japan). 34(7)
In a 24-year-old woman with mitochondrial encephalomyopathy presenting hypertrophic cardiomyopathy, microscopical examination of myocardial biopsy specimen disclosed severe vacuolar degeneration of myocardium and aggregates of enlarged mitochondria w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ce89daf6707d3873c6092f61b59cbb
https://pubmed.ncbi.nlm.nih.gov/7496082
https://pubmed.ncbi.nlm.nih.gov/7496082
Autor:
Takayuki Ozawa, Sergey A. Kovalenko, Makoto Yoneda, Toshihiro Obayashi, Masashi Tanaka, Satoru Sugiyama
Publikováno v:
Musclenerve. Supplement. 3
Mutations occur in mitochondrial DNA (mtDNA) in a strand-asymmetric manner. The suppressed usage of cysteine residues in the H-strand-encoded subunits can be ascribed to the mutational instability of the codon for cysteine. The usage of cysteine was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::473a05d9ad64b421227fc11f96cafeaa
https://pubmed.ncbi.nlm.nih.gov/7603519
https://pubmed.ncbi.nlm.nih.gov/7603519
Autor:
Nobuakira Takeda, Keishiro Kawamura, Takayuki Ito, Kazuki Hattori, Yoshinori Koga, Makoto Nagano, Satoru Sugiyama, Shinji Itoyama, Taihei Tanaka, Masashi Tanaka, Takayuki Ozawa, Hironori Toshima, Hirofumi Deguchi, Toshihiro Obayashi
Publikováno v:
American heart journal. 124(5)
Recent advances suggest that mutations in nuclear DNA are involved in the etiology of autosomal dominant hypertrophic cardiomyopathy. Mitochondria have their own DNA, and mutations in mitochondrial DNA have been shown to contribute to the genesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b35921c989b2ad9b222b7dd94e4975b9
https://pubmed.ncbi.nlm.nih.gov/1442494
https://pubmed.ncbi.nlm.nih.gov/1442494
Autor:
Takayuki Ito, Toshihiro Obayashi, Satoru Sugiyama, Takayuki Ozawa, Masashi Tanaka, Kazuki Hattori
Publikováno v:
Japanese circulation journal. 56(10)
Deletions and point mutations of mitochondrial DNA (mtDNA) of patients with dilated or hypertrophic cardiomyopathy were analyzed using the polymerase chain reaction and fluorescence-based direct sequencing. The patients included are with hypertrophic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c4a47917b27c703a1d61a7b748aa685
https://pubmed.ncbi.nlm.nih.gov/1433821
https://pubmed.ncbi.nlm.nih.gov/1433821
Autor:
Toshihiro Obayashi, Takayuki Ozawa, Kazuki Hattori, Masashi Tanaka, Satoru Sugiyama, Takayuki Ito
Publikováno v:
New Aspects in the Treatment of Failing Heart ISBN: 9784431682219
Mitochondria have their own DNA, 16,569 base pairs, which encodes mRNA genes for 13 subunits of four complexes of the oxidative phosphorylation system, 22 tRNAs required for translation of their mRNA, and two rRNA [1]. The mutation rate in mitochondr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca0cc8fd9770970cf0dbec953f60f3e0
https://doi.org/10.1007/978-4-431-68219-6_8
https://doi.org/10.1007/978-4-431-68219-6_8
Autor:
Takayuki Ito, Hiroyasu Esumi, Masaaki Takasawa, Kazuki Hattori, Satoru Sugiyama, Takayuki Ozawa, Toshihiro Obayashi
Publikováno v:
Journal of Molecular and Cellular Cardiology. 24:184
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9aa722f8c9ef06b01c1b669b3e5e6fe4
https://doi.org/10.1016/0022-2828(92)90576-l
https://doi.org/10.1016/0022-2828(92)90576-l