Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Toshihiro Matsuzaki"'
Autor:
Katsuhiko Noguchi, Toshihiro Matsuzaki, Mayuko Sakanashi, Naobumi Hamadate, Taro Uchida, Mika Kina-Tanada, Haruaki Kubota, Junko Nakasone, Matao Sakanashi, Shinichiro Ueda, Hiroaki Masuzaki, Shogo Ishiuchi, Yusuke Ohya, Masato Tsutsui
Publikováno v:
Journal of Pharmacological Sciences, Vol 127, Iss 2, Pp 217-222 (2015)
Recent epidemiological studies have demonstrated that coffee drinking is associated with reduced mortality of cardiovascular disease. However, its precise mechanisms remain to be clarified. In this study, we examined whether single ingestion of caffe
Externí odkaz:
https://doaj.org/article/e1377cd0d5564a7b8c98ed790563cb26
Autor:
Naobumi Hamadate, Katsuhiko Noguchi, Mayuko Sakanashi, Toshihiro Matsuzaki, Junko Nakasone, Matao Sakanashi
Publikováno v:
Journal of Pharmacological Sciences, Vol 107, Iss 1, Pp 49-56 (2008)
Tetrahydrobiopterin (BH4) deficiency has been suggested to be an important factor in vascular endothelial dysfunction. In this study, we investigated the influence of decreased BH4 level produced by administration of 2,4-diamino-6-hydroxypyrimidine (
Externí odkaz:
https://doaj.org/article/06346dff34e145469183e7aa18b18979
Autor:
Yusuke Ohya, Masato Tsutsui, Hiroaki Shimokawa, Junko Nakasone, Mayuko Sakanashi, Katsuhiko Noguchi, Akira Arasaki, Toshihiro Matsuzaki, Mika Kina-Tanada
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO2-7
Autor:
Akihide Tanimoto, Taro Uchida, Shiro Maeda, Tadashi Kaname, Yuji Taira, Akira Arasaki, Hiroaki Masuzaki, Katsuhiko Noguchi, Kimio Satoh, Masayuki Matsushita, Yuichi Totsuka, Chisayo Kozuka, Toshihiro Matsuzaki, Junichi Omura, Masato Tsutsui, Haruaki Kubota, Shin ichiro Kina, Nobuyuki Yanagihara, Junko Nakasone, Mika Kina-Tanada, Mayuko Sakanashi, Hiroaki Shimokawa, Hajime Sunakawa, Masayoshi Ishida, Yusuke Ohya
Publikováno v:
Diabetologia. 60:1138-1151
Nitric oxide (NO) is synthesised not only from l-arginine by NO synthases (NOSs), but also from its inert metabolites, nitrite and nitrate. Green leafy vegetables are abundant in nitrate, but whether or not a deficiency in dietary nitrite/nitrate spo
Autor:
Taro Uchida, Mayuko Sakanashi, Shinichiro Ueda, Hiroaki Masuzaki, Toshihiro Matsuzaki, Matao Sakanashi, Naobumi Hamadate, Haruaki Kubota, Yusuke Ohya, Masato Tsutsui, Junko Nakasone, Katsuhiko Noguchi, Mika Kina-Tanada, Shogo Ishiuchi
Publikováno v:
Journal of Pharmacological Sciences, Vol 127, Iss 2, Pp 217-222 (2015)
Recent epidemiological studies have demonstrated that coffee drinking is associated with reduced mortality of cardiovascular disease. However, its precise mechanisms remain to be clarified. In this study, we examined whether single ingestion of caffe
Autor:
Kanako Kuniyoshi, Jyunko Nakasone, Toshihiro Matsuzaki, M. Kakinohana, Katsuhiko Noguchi, Masato Tsutsui, Kazuhiro Sugahara, Haruaki Kubota, Mayuko Sakanashi, Hiroaki Shimokawa
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 92:2
Publikováno v:
Vascular Pharmacology. 58:319-325
The objective of this study was to determine the mechanism by which Na(+)/H(+) exchanger (NHE) inhibitors induce vasodilatation. The NHE inhibitors, 5-(N,N-dimethyl)-amiloride (DMA), cariporide, and amiloride, evoked endothelium-dependent relaxation
Autor:
Hiroaki Masuzaki, Toshihiro Matsuzaki, Katsuhiko Noguchi, Akihide Tanimoto, Haruaki Kubota, Makiko Sakanashi, Matao Sakanashi, Mayuko Sakanashi, Nobuyuki Yanagihara, Kumiko Arakaki, Masato Tsutsui, Junko Nakasone, Taro Uchida, Mika Kina-Tanada, Kazuhiro Sugahara, Yusuke Ohya, Shogo Ishiuchi
Publikováno v:
Circulation Journal. 77:1827-1837
Background Hormone replacement therapy has failed to reduce ischemic cardiovascular events in climacteric women. To explore alternative therapy, we examined whether san'o-shashin-to (TJ-113), a kampo medicine, ameliorates cardiac ischemia-reperfusion
Autor:
Junko Nakasone, Satoshi Yamashiro, Matao Sakanashi, Tatsushi Itomine, Toshihiro Matsuzaki, Makie Higuchi, Kanako Miyagi, Mayuko Sakanashi, Katsuhiko Noguchi
Publikováno v:
Arzneimittelforschung. 50:1078-1083
The influence of extracellular Ca 2+ concentration on contractile responses of aortae isolated from diabetic rats to KCl and α-adrenoceptor agonists was compared with that of non-diabetic rat aortae. Diabetic rats 6 weeks after administration of str
Autor:
Kazuhiro Sugahara, Naobumi Hamadate, Toshihiro Matsuzaki, Shogo Ishiuchi, Haruaki Kubota, Mayuko Sakanashi, Katsuhiko Noguchi, Taro Uchida, Matao Sakanashi, Masato Tsutsui, Junko Nakasone, Kumiko Arakaki, Hiroaki Masuzaki, Yusuke Ohya
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 301:H721-H729
An elevation of oxidized forms of tetrahydrobiopterin (BH4), especially dihydrobiopterin (BH2), has been reported in the setting of oxidative stress, such as arteriosclerotic/atherosclerotic disorders, where endothelial nitric oxide synthase (eNOS) i