Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Toshihiro Inubushi"'
Autor:
Namiki Nagata, Hiroshi Kurosaka, Kotaro Higashi, Masaya Yamaguchi, Sayuri Yamamoto, Toshihiro Inubushi, Miho Nagata, Yasuki Ishihara, Ayumi Yonei, Yohei Miyashita, Yoshihiro Asano, Norio Sakai, Yasushi Sakata, Shigetada Kawabata, Takashi Yamashiro
Publikováno v:
Human Genome Variation, Vol 11, Iss 1, Pp 1-4 (2024)
Abstract Germline loss-of-function mutations in USP9X have been reported to cause a wide spectrum of congenital anomalies. Here, we report a Japanese girl with a novel heterozygous nonsense mutation in USP9X who exhibited intellectual disability with
Externí odkaz:
https://doaj.org/article/b9393595a854481382cc04985167cc60
Autor:
Naoki Yoshida, Toshihiro Inubushi, Takumi Hirose, Gozo Aoyama, Hiroshi Kurosaka, Takashi Yamashiro
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/9cb71f21d5cf468480c6ae24f2895168
Autor:
Toshihiro Inubushi, Nag Priyanka, Masakatsu Watanabe, Yusuke Takahashi, Shinnosuke Kusano, Hiroshi Kurosaka, Silvana Papagerakis, Petros Papagerakis, Mikako Hayashi, Takashi Yamashiro
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Heparan sulfate proteoglycans (HSPGs) surround the surface of odontoblasts, and their modification affects their affinity for Wnt ligands. This study proposes applying Matching Transformation System® (MA-T), a novel chlorinated oxidant, to enhance d
Externí odkaz:
https://doaj.org/article/f443846049b34432ab7cd321498f9c0c
Autor:
Eriko Nakamura, Kenji Hata, Yoshifumi Takahata, Hiroshi Kurosaka, Makoto Abe, Takaya Abe, Miho Kihara, Toshihisa Komori, Sachi Kobayashi, Tomohiko Murakami, Toshihiro Inubushi, Takashi Yamashiro, Shiori Yamamoto, Haruhiko Akiyama, Makoto Kawaguchi, Nobuo Sakata, Riko Nishimura
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Nakamura et al. used expression studies to identify an enrichment of Zfhx4 in cartilage and revealed through global gene knock-down that it is required for proper endochondral ossification in mice. They further demonstrated a physical and genetic int
Externí odkaz:
https://doaj.org/article/c38c2a6d2d8844b3af9e0bfa858e2f81
Autor:
Toshihiro Inubushi, Yuichiro Nakanishi, Makoto Abe, Yoshifumi Takahata, Riko Nishimura, Hiroshi Kurosaka, Fumitoshi Irie, Takashi Yamashiro, Yu Yamaguchi
Publikováno v:
PLoS Genetics, Vol 18, Iss 7, p e1009765 (2022)
Hyaluronan (HA) is a major extracellular matrix component whose tissue levels are dynamically regulated during embryonic development. Although the synthesis of HA has been shown to exert a substantial influence on embryonic morphogenesis, the functio
Externí odkaz:
https://doaj.org/article/0cd697f61c53400785290da4a9539e1f
Autor:
Toshihiro Inubushi, Ayaka Fujiwara, Takumi Hirose, Gozo Aoyama, Toshihiro Uchihashi, Naoki Yoshida, Yuki Shiraishi, Yu Usami, Hiroshi Kurosaka, Satoru Toyosawa, Susumu Tanaka, Tetsuro Watabe, Mikihiko Kogo, Takashi Yamashiro
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 2 (2022)
Cleft palate is one of the major congenital craniofacial birth defects. The etiology underlying the pathogenesis of cleft palate has yet to be fully elucidated. Dissociation of the medial edge epithelium (MEE) at the contacting region of palatal shel
Externí odkaz:
https://doaj.org/article/805075ca0a4a4c0b9d653a0aa7fbbc3a
Autor:
Shunryou Yanagisawa, Karin Nagasaki, Chanbora Chea, Toshinori Ando, Nurina Febriyanti Ayuningtyas, Toshihiro Inubushi, Atsushi Ishikado, Hiromichi Imanaka, Eiji Sugiyama, Ichiro Takahashi, Mutsumi Miyauchi, Takashi Takata
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0263254 (2022)
Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammatory bone destruction in which tumor necrosis factor alpha (TNF-α) plays a key role. Bovine lactoferrin (bLF) is a multifunctional protein with anti-inflammatory and immunom
Externí odkaz:
https://doaj.org/article/4acf2dc8bae94106a8de521df161a395
Autor:
Chanbora Chea, Mutsumi Miyauchi, Toshihiro Inubushi, Kana Okamoto, Sivmeng Haing, Takashi Takata
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 562 (2023)
Lactoferrin (LF), an iron-binding glycoprotein, has been reported to have anticancer properties. However, the molecular mechanisms behind its anticancer effects on oral squamous cell carcinoma (OSCC) have not yet been elucidated. Therefore, we aimed
Externí odkaz:
https://doaj.org/article/14c79dcd5473489e9a12c8d156f0c980
Autor:
Nurina Febriyanti Ayuningtyas, Chanbora Chea, Toshinori Ando, Karina Erda Saninggar, Keiji Tanimoto, Toshihiro Inubushi, Nako Maishi, Kyoko Hida, Masanobu Shindoh, Mutsumi Miyauchi, Takashi Takata
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 165 (2023)
Tumor angiogenesis is essential for tumor progression. The inhibition of tumor angiogenesis is a promising therapy for tumors. Bovine lactoferrin (bLF) has been reported as an anti-tumor agent. However, bLF effects on tumor angiogenesis are not well
Externí odkaz:
https://doaj.org/article/53599e68a9154c01b41fd243c29d80de
Autor:
Sayuri Yamamoto, Hiroshi Kurosaka, Jiro Miura, Gozo Aoyama, Safiye Esra Sarper, Ayaka Oka, Toshihiro Inubushi, Kohei Nakatsugawa, Yu Usami, Satoru Toyosawa, Takashi Yamashiro
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Epithelial fusion is critical in palatogenesis, and incomplete fusion results in various type of facial cleft, depending on the region that fails to fuse. In mammalian palatogenesis, the bilateral secondary palatal processes fuse in the middle of the
Externí odkaz:
https://doaj.org/article/50ce6048223c4027a13c80f37b3cbb7d