Zobrazeno 1 - 10
of 296
pro vyhledávání: '"Toshihiro, Sato"'
Autor:
Masaki Kumondai, Reika Ogawa, Nagomi Hayashi, Yurika Ishida, Hanae Oshikiri, Yuji Sato, Masafumi Kikuchi, Yu Sato, Toshihiro Sato, Masamitsu Maekawa, Nariyasu Mano
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 4, Pp n/a-n/a (2024)
Abstract Lenvatinib (LEN), a multitarget tyrosine kinase inhibitor used in various cancer treatments, is mainly metabolized by cytochrome P450 3A (CYP3A) enzymes. The importance of therapeutic drug monitoring (TDM) in patients administered LEN has be
Externí odkaz:
https://doaj.org/article/3c3b7eda38744636833b54cae65ec9d1
Autor:
Minami Yamauchi, Masamitsu Maekawa, Toshihiro Sato, Yu Sato, Masaki Kumondai, Mio Tsuruoka, Jun Inoue, Atsushi Masamune, Nariyasu Mano
Publikováno v:
Metabolites, Vol 14, Iss 9, p 513 (2024)
Imaging tests, tumor marker (TM) screening, and biochemical tests provide a definitive diagnosis of hepatocellular carcinoma (HCC). However, some patients with HCC may present TM-negative results, warranting a need for developing more sensitive and a
Externí odkaz:
https://doaj.org/article/f6e718526f93447587c02a0a64d33fa2
Autor:
Yu Sato, Hiroki Kondo, Yuji Sato, Ai Abe, Masafumi Kikuchi, Toshihiro Sato, Masaki Kumondai, Kohei Yoshikawa, Yoshihiro Hayakawa, Masamitsu Maekawa, Nariyasu Mano
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1138 (2024)
Therapeutic drug monitoring (TDM) is a personalized treatment approach that involves optimizing drug dosages based on patient-specific factors, such as drug plasma concentrations, therapeutic efficacy, or adverse reactions. The plasma concentration o
Externí odkaz:
https://doaj.org/article/797592a7facb4fbb992499f588035371
Autor:
Masaki Maruyama, Suguru Miida, Toshihiro Sato, Takazumi Kimura, Azuma Watanabe, Hideo Watanabe, Masafumi Nishizawa, Kyohei Horikawa, Takahiro Kajiwara, Yusuke Karasawa, Yuko Hasebe, Kazutaka Nozawa, Shuji Terai
Publikováno v:
JGH Open, Vol 7, Iss 9, Pp 610-617 (2023)
Abstract Background and Aim Stimulant laxatives may cause electrolyte abnormalities, dehydration, and abdominal pain; their long‐term use can lead to tolerance and subsequent refractory constipation. We investigated the effectiveness, safety, and q
Externí odkaz:
https://doaj.org/article/a859dfd9f6cc48efa567bebe5ac1dc2a
Autor:
Masanori Akashi, Daiki Miyazaki, Kazuaki Hashimoto, Shogo Fukutomi, Shoichiro Arai, Yuichi Goto, Toshihiro Sato, Hisamune Sakai, Toru Hisaka
Publikováno v:
Surgical Case Reports, Vol 9, Iss 1, Pp 1-8 (2023)
Abstract Background Among congenital anomalies of the portal venous system, prepancreatic postduodenal portal vein (PPPV) is very rare and has only been reported to date. Herein, we report a case of PPPV identified in preoperative examinations for he
Externí odkaz:
https://doaj.org/article/a78c4ff35ac44b4c89b47192a65a51ba
Autor:
Haremaru Kubo, Shojiro Sawada, Michihiro Satoh, Yoichiro Asai, Shinjiro Kodama, Toshihiro Sato, Seitaro Tomiyama, Junro Seike, Kei Takahashi, Keizo Kaneko, Junta Imai, Hideki Katagiri
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Insulin like growth factor-1 (IGF-1) plays important roles in metabolic functions, especially in adulthood. Additionally, obese subjects are reportedly predisposed to having low absolute IGF-1 levels. However, the prevalence and clinical cha
Externí odkaz:
https://doaj.org/article/d316480ed876402eae1d68b175b6139b
Autor:
Masato Kohata, Junta Imai, Tomohito Izumi, Junpei Yamamoto, Yohei Kawana, Akira Endo, Hiroto Sugawara, Junro Seike, Haremaru Kubo, Hiroshi Komamura, Toshihiro Sato, Shinichiro Hosaka, Yuichiro Munakata, Yoichiro Asai, Shinjiro Kodama, Kei Takahashi, Keizo Kaneko, Hideki Katagiri
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 10, Pp 1666-1676 (2022)
ABSTRACT Aims/Introduction Whether basal β‐cell proliferation during adulthood is involved in maintaining sufficient β‐cell mass, and if so, the molecular mechanism(s) underlying basal β‐cell proliferation remain unclear. FoxM1 is a critical
Externí odkaz:
https://doaj.org/article/d05dbe7f5379427983242b019fd55228
Autor:
Tensei Hirasawa, Masafumi Kikuchi, Shinya Takasaki, Masaki Kumondai, Yu Sato, Toshihiro Sato, Eishi Imoto, Yoshihiro Hayakawa, Masamitsu Maekawa, Nariyasu Mano
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e16926- (2023)
Many types of oral molecular-targeted anticancer drugs are clinically used in cancer genomic medicine. Combinations of multiple molecular-targeted anticancer drugs are also being investigated, expecting to prolong the survival of patients with cancer
Externí odkaz:
https://doaj.org/article/5548934ceb984d27b8cf4fd6c31ce6d8
Autor:
Toshihiro Sato, Ayaka Yagi, Minami Yamauchi, Masaki Kumondai, Yu Sato, Masafumi Kikuchi, Masamitsu Maekawa, Hiroaki Yamaguchi, Takaaki Abe, Nariyasu Mano
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 991 (2024)
Flavonoids have garnered attention because of their beneficial bioactivities. However, some flavonoids reportedly interact with drugs via transporters and may induce adverse drug reactions. This study investigated the effects of food ingredients on o
Externí odkaz:
https://doaj.org/article/0497556de20d400491c0339bc4826882
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 7, Pp 1161-1174 (2022)
Abstract Aims/Introduction Many East Asians with type 2 diabetes are elderly and have a low body mass index (BMI), especially in 'super‐aged' populations, such as Japan. This post‐hoc analysis assessed once‐weekly semaglutide efficacy and safet
Externí odkaz:
https://doaj.org/article/c6ae2524a7344751b610849a1437e6e2