Zobrazeno 1 - 10 of 542 pro vyhledávání: '"Toshihiro, Nohara"'
1
Akademický článek
Saponin Esculeoside A and Aglycon Esculeogenin A from Ripe Tomatoes Inhibit Dendritic Cell Function by Attenuation of Toll-like Receptor 4 Signaling
Autor: Jian-Rong Zhou, Shigenori Kinno, Kenta Kaihara, Madoka Sawai, Takumi Ishida, Shinji Takechi, Jun Fang, Toshihiro Nohara, Kazumi Yokomizo
Publikováno v: Nutrients, Vol 16, Iss 11, p 1699 (2024)
Dendritic cells (DCs) can initiate immune response through the presenting antigens to naïve T lymphocytes. Esculeoside A (EsA), a spirosolane glycoside, is reported as a major component in the ripe fruit of tomato. Little is known about the effect o
Externí odkaz: https://doaj.org/article/b46b7d9618e7478392be83b20830a95a
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2
Akademický článek
Different effects on the tonus of colon and ileum isolated from mouse by resin glycoside (pharbitin) of Pharbitidis Semen
Autor: Jian-Rong Zhou, Naofumi Tokutomi, Yuusuke Satou, Shin Yasuda, Hideki Kinoshita, Toshihiro Nohara, Kazumi Yokomizo, Masateru Ono
Publikováno v: BMC Complementary Medicine and Therapies, Vol 22, Iss 1, Pp 1-7 (2022)
Abstract Background Pharbitidis Semen (the seeds of Pharbitis nil), traditionally used as a purgative in Japan, China and Korea, contains a resin glycoside fraction named pharbitin, which is known as a purgative ingredient. Due to the complex nature
Externí odkaz: https://doaj.org/article/5d96df1d16d14582bc10a1296df8ae0d
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3
Akademický článek
Garlicnin B1, an Active Cyclic Sulfide from Garlic, Exhibits Potent Anti-Inflammatory and Anti-Tumor Activities
Autor: Shanghui Gao, Kai Yang, Toshihiro Nohara, Tsuyoshi Ikeda, Jian-Rong Zhou, Kazumi Yokomizo, Jun Fang
Publikováno v: Antioxidants, Vol 12, Iss 4, p 869 (2023)
This study aimed to investigate the pharmacological activities of garlicnin B1, a cyclic sulfide compound found abundantly in garlic and structurally similar to onionin A1, which has been shown to possess strong anti-tumor effects. In vitro studies d
Externí odkaz: https://doaj.org/article/cb3935d2aa85460e86ccc91ab9424875
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4
Onionin A inhibits small-cell lung cancer proliferation through suppressing STAT3 activation induced by macrophages-derived IL-6 and cell–cell interaction with tumor-associated macrophage
Autor: Remi Mito, Toyohisa Iriki, Yukio Fujiwara, Cheng Pan, Tsuyoshi Ikeda, Toshihiro Nohara, Makoto Suzuki, Takuro Sakagami, Yoshihiro Komohara
Publikováno v: Human Cell. 36:1068-1080
Tumor-associated macrophage (TAM)-derived IL-6 is involved in small-cell lung cancer (SCLC) progression and chemoresistance via the activation of signal transducer and activator of transcription 3 (STAT3) in the tumor microenvironment. This study aim
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74f7666a294383f958f9d32f33df0358
https://doi.org/10.1007/s13577-023-00895-6
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5
Akademický článek
Ripe Tomato Saponin Esculeoside A and Sapogenol Esculeogenin A Suppress CD4+ T Lymphocyte Activation by Modulation of Th2/Th1/Treg Differentiation
Autor: Jian-Rong Zhou, Rie Yamada, Erina Huruiti, Nozomi Kitahara, Honami Nakamura, Jun Fang, Toshihiro Nohara, Kazumi Yokomizo
Publikováno v: Nutrients, Vol 14, Iss 10, p 2021 (2022)
We report that esculeoside A (EsA), a glycoside and a major component in ripe tomato fruit, ameliorated experimental dermatitis in mice. However, the underlying immunologic molecular mechanisms are unknown. The present study examined its underlying i
Externí odkaz: https://doaj.org/article/0198c7e9619042249c189b1dea479ce5
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9
Thiolane-type sulfides from garlic, onion, and Welsh onion
Autor: Daisuke Nakano, Masateru Ono, Toshihiro Nohara, Mona El-Aasr, Junei Kinjo, Tsuyoshi Ikeda, Yukio Fujiwara
Publikováno v: Journal of Natural Medicines
In this paper, we review our work in the last 10 years wherein we examined the sulfides in the acetone extracts of garlic (Allium sativum), onion (A. cepa), and Welsh onion (A. fistulosum), obtained and characterized the structures of new sulfides, t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e68ed619ec1e9b1e76f78bc8179f15ad
http://europepmc.org/articles/PMC8397685
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10
Two new triterpenoids from the leaves and stems of Lantana camara
Autor: Masateru Ono, Aimi Sakata, Shuhei Tsutsumi, Masafumi Okawa, Mizuki Shimode, Mayu Miyajima, Hitoshi Yoshimitsu, Shin Yasuda, Asami Hashimoto, Toshihiro Nohara, Junei Kinjo, Chisato Furusawa
Publikováno v: Natural Product Research. 35:3757-3765
Two new oleanane-type triterpenoids with an epoxy bridge between C-3 and C-25, named lantacamaric acids A and B, were isolated from the leaves and stems of Lantana camara L. (Verbenaceae). In addition, seven known triterpenoids, two known iridoid gly
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b3820389ffde609d678c3484c08d9c
https://doi.org/10.1080/14786419.2020.1736063
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