Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Toshihiko Morikage"'
Autor:
Nagahiro Saijo, Yasuhiro Fujiwara, Yasutsuna Sasaki, Toshihiko Morikage, Terumi Takahashi, Kazuo Kasahara, Kazuto Nishio, Yoshikazu Sugimoto, Tohru Ohmori, Sei Ohta
Publikováno v:
Japanese Journal of Cancer Research : Gann
A cisplatin‐resistant non‐small cell lung cancer cell line, PC‐14/CDDP, was established from PC‐14 by stepwise escalation of CDDP concentrations in vitro. PC‐14/CDDP cells were 11.4‐fold more resistant to CDDP compared with PC‐14 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352ca4fcfd1253c4afc5bdc727b90d5e
http://europepmc.org/articles/PMC5919029
http://europepmc.org/articles/PMC5919029
Autor:
Nagahiro Saijo, Yuichiro Takeda, Naohiro Kubota, Toshihiko Morikage, Kaoru Abe, Kazuto Nishio, Tohru Ohmori, Keizaburo Miki, Yasuhiro Fujiwara
Publikováno v:
Japanese Journal of Cancer Research : Gann
A cyclic adenosine 3′,5′-monophosphate (cAMP) analogue, 8-chloro-cAMP (8-Cl-cAMP), had a collateral growth-inhibitory effect on a cis-diamminedichloroplatinum(II) (CDDP)-resistant human cancer cell lines (PC-14/CDDP). The non-selective analogues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57fc14723e21af8b6598d16965aa13a7
http://europepmc.org/articles/PMC5918934
http://europepmc.org/articles/PMC5918934
Publikováno v:
Oncology. 48:431-437
We examined death rates in Fisher rats when chemotherapeutic drugs were administered in a prescribed amount by either a single or divided dose. Lower death rates were observed when nimustine hydrochloride (ACNU) was given in a divided dose, or when c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7e86bbad3c0fe96eecc7f1a521fde19
https://doi.org/10.1159/000226974
https://doi.org/10.1159/000226974
Publikováno v:
The Tohoku Journal of Experimental Medicine. 163:47-57
In order to make clear the characteristic biological properties of IL-1 alpha, its protective capabilities on bacteria-induced and LPS-induced lethality were compared with other BRMs in BALB/c mice. Pretreatment with IL-1 alpha (i.p., s.c.) or OK-432
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::773df8f8ac6f338dca706d758588fafc
https://doi.org/10.1620/tjem.163.47
https://doi.org/10.1620/tjem.163.47
Autor:
Akimi Takashima, Keiko Konishi, Saburo Yano, Toshihiko Morikage, Akira Kawasaki, Tatsuhiko Kashii, Hitoshi Hirata, Yutaka Mizushima, Kiyoshi Hoshino
Publikováno v:
Japanese Journal of Medicine. 29:146-155
A survey regarding the revelation of the diagnosis of cancer to patients was conducted on 116 medical doctors (MD), 206 paramedical personnel (PP) and 789 lay persons (LP) in June 1989 in Toyama prefecture, Japan. When asked in the case that their pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55aa528f30f0baea7a75901be9f66b0e
https://doi.org/10.2169/internalmedicine1962.29.146
https://doi.org/10.2169/internalmedicine1962.29.146
Autor:
Kazuto Nishio, Nagahiro Saijo, Hisanobu Niitani, Tohru Ohmori, Yuichiro Takeda, Kaoru Miura, Naohiro Kubota, Shoji Kudoh, Toshihiko Morikage
Publikováno v:
International journal of cancer. 58(6)
Okadaic acid (OA), a specific protein phosphatase inhibitor, has various biological functions. To elucidate the mechanism of OA resistance, we have established a small-cell lung-cancer subline (H69/OA100) resistant to the growth-inhibitory effect of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132addc5f21b31d17530bf05d2eccbe6
https://pubmed.ncbi.nlm.nih.gov/7927883
https://pubmed.ncbi.nlm.nih.gov/7927883
Autor:
Tohru Ohmori, Sei Ohta, Yuichiro Takeda, Toshihiko Morikage, Nagahiro Saijo, Kazuto Nishio, Naohiro Kubota, Kazunaga Yazawa
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 203(2)
The effect of ascorbic acid 6-docosahexaenoate (DHA-VC) on the phospholipase-C-mediated hydrolysis of phosphatidylcholine was investigated. In human non-small cell lung cancer cells (PC-14) exposed to DHA-VC for 24 hr, a dose-dependent increase in ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c59d4c1b2b9c61c034070c726744dba
https://pubmed.ncbi.nlm.nih.gov/8389049
https://pubmed.ncbi.nlm.nih.gov/8389049
Autor:
Nagahiro Saijo, Yuichiro Ohe, Tohru Ohmori, Toshihiko Morikage, Yasuhiro Fujiwara, Yoshikazu Sugimoto, Kazuto Nishio
Publikováno v:
British Journal of Cancer
A cisplatin(CDDP)-resistant subline of a human lung cancer cell line, PC-7/CDDP, was 4.7-fold more resistant to CDDP than the parent line in a colony-forming assay. The sensitivity of this cell line to anthracyclines, vinca-alkaloid, etoposide, mitom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746993d1d2bf7b1e2e7925aed47d5cb3
https://pubmed.ncbi.nlm.nih.gov/1319727
https://pubmed.ncbi.nlm.nih.gov/1319727
Autor:
Akira Kawasaki, Shoko Matsui, Akihito Yokoyama, Yutaka Mizushima, Toshihiko Morikage, Hiroshi Tsuji, Saburo Izumi, Saburo Yano, Yoshimasa Kin, Hitoshi Hirata
Publikováno v:
Tumori. 77(4)
To characterize basic fetoprotein (BFP) as a new tumor marker, we measured serum levels of BFP and 5 other tumor markers (CA19-9, CEA, NSE, SCC, and TPA) concomitantly in 65 patients with lung cancer, 57 patients with benign pulmonary disease, and 40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f8bdadd212a25b3af6ed58d28ac71aa
https://pubmed.ncbi.nlm.nih.gov/1746051
https://pubmed.ncbi.nlm.nih.gov/1746051
Autor:
Toshihiko Morikage, Tohru Ohmori, Masami Bungo, Mitsuji Yoshida, Yasuhiro Fujiwara, Nagahiro Saijo, Motoko Inomata, Kazuto Nishio
Publikováno v:
Japanese Journal of Cancer Research : Gann
The potentiation of anticancer agents by non-anticancer drugs is one of the possible strategies for overcoming cellular resistance to chemotherapy. In order to overcome cis-diamminedichloroplatinum-(II) (CDDP) resistance, we evaluated the sensitizing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60da969018ab63b43f0a27fe3d1e96bf
https://pubmed.ncbi.nlm.nih.gov/1649814
https://pubmed.ncbi.nlm.nih.gov/1649814