Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Toshihiko MORIMOTO"'
Publikováno v:
Folia Pharmacologica Japonica. 96:65-71
The effect of Y-516 on the hyperactivity induced by dopamine injected bilaterally into the nucleus accumbens was compared with those of clocapramine (CCP), haloperidol (HPD) and chlorpromazine (CPZ). Dopamine (5-50 micrograms) injected into the nucle
Autor:
Shuzo Takehara, Hiroshi Yasumatsu, Toshihiko Morimoto, Masatake Fujimura, Kenji Hashimoto, Koreichi Kimura, Makoto Kuriyama, Keiji Yamagami, Hiroshi Tanaka
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 26(4)
The neuropharmacological profile of Y-931, 8-fluoro-12- (4-methylpiperazin-1-yl)- 6H-[1]benzothieno [2,3-b][1,5]benzodiazepine maleate, was investigated in comparison with those of typical and claimed atypical antipsychotic drugs. Similar to clozapin
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 99(3)
Effects of mosapramine (Y-516), a new dopamine D2 antagonist, on reverse tolerance (sensitization) after repeated administration of methamphetamine (MAP; 2 mg/kg, s.c.) were investigated by means of ambulatory activity in mice; and they were compared
Autor:
Masao KOIDA, Yoshinobu YAMAMOTO, Hiromichi NAKAMUTA, Junko MATSUO, Masaharu OKAMOTO, Toshihiko MORIMOTO, Jay K. SEYLER, Ronald C. ORLOWSKI
Publikováno v:
Japanese Journal of Pharmacology. 32:981-986
Autor:
Toshihiko Morimoto, Takemi Fukuda, Yasuto Morimoto, Hidenori Shoji, Michihide Setoguchi, Tetsuya Tahara, Shu Murakami
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 94(5)
N-[(1-butyl-2-pyrrolidinyl)methyl]-2-methyl-5-sulfamoyl-2,3- dihydrobenzofuran-7-carboxamide hydrochloride (Y-20024) was synthesized in our laboratories in anticipation of developing a new psychotropic drug. In the present study, the pharmacological
Intracerebroventricular injection of 125I-salmon calcitonin in rats: fate, anorexia and hypocalcemia
Autor:
Ronald C. Orlowski, Glenn L. Stahl, Masao Koida, Masaharu Okamoto, Toshihiko Morimoto, Hiromichi Nakamuta
Publikováno v:
Japanese journal of pharmacology. 37(1)
Intracerebroventricular (i.c.v.) injection of 19 pmol/rat or more of salmon calcitonin (sCT) or iodinated sCT suppressed spontaneous intake of food and water in a dose-dependent manner. Tail-whipping was a peculiar behavior which concomitantly develo
Publikováno v:
Japanese Journal of Pharmacology. 36:538-539
Publikováno v:
Japanese Journal of Pharmacology. 36:215
Publikováno v:
Japanese Journal of Pharmacology. 33:199
It was attempted to defferentially label the rat brain calcitonin receptor using a photoactive derivative of salmon calcitonin (sCT) in which N-(β -aminoethyl)-4- azido-2-nitroaniline was introduced to the Gln-residue(s) of the hormone as described