Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Toshihiko Kumazawa"'
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Japanese people have been consuming miso soup over generations; it is beneficial for health and longevity. In this study, Tetragenococcus halophilus No. 1 in miso was found to possess salient immunomodulatory functions. Recently, we also demonstrated
Externí odkaz:
https://doaj.org/article/e296ec4de7604f4d9828a76d6792fe01
Autor:
Kunihiko Kotake, Toshihiko Kumazawa, Kiminori Nakamura, Yu Shimizu, Tokiyoshi Ayabe, Takahiro Adachi
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
In Japan, there is a long history of consumption of miso, a fermented soybean paste, which possesses beneficial effects on human health. However, the mechanism behind these effects is not fully understood. To clarify the effects of miso on immune cel
Externí odkaz:
https://doaj.org/article/479f4ee0ecc5416aa9842349038620cc
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208821 (2018)
Tetragenococcus halophilus is a halophilic lactic acid bacterium that exists in the traditional Japanese seasoning miso-a fermented soy paste. Considering the popularity of miso as a component of healthy diet, we attempted to evaluate the immunoregul
Externí odkaz:
https://doaj.org/article/69ee6b393f694a4190a163b2a0c0679c
Autor:
Takashi Nagaishi, Taro Watabe, Kunihiko Kotake, Toshihiko Kumazawa, Tomomi Aida, Kohichi Tanaka, Ryuichi Ono, Fumitoshi Ishino, Takako Usami, Takamasa Miura, Satomi Hirakata, Hiroko Kawasaki, Naoya Tsugawa, Daiki Yamada, Kazuhiro Hirayama, Soichiro Yoshikawa, Hajime Karasuyama, Ryuichi Okamoto, Mamoru Watanabe, Blumberg, Richard S.
Publikováno v:
Gut; Mar2022, Vol. 71 Issue 3, p487-496, 10p
Autor:
Toshihiko KUMAZAWA, Kunihiko KOTAKE, Atsuhisa NISHIMURA, Noriyuki ASAI, Tsukasa UGAJIN, Hiroo YOKOZEKI, Takahiro ADACHI
Publikováno v:
Bioscience of Microbiota, Food & Health; 2020, Vol. 39 Issue 1, p1-9, 9p
Autor:
Hiromi Nishitani, Toshihiko Kumazawa, Yukiharu Matsumoto, Yoshiaki Tagawa, Tsukasa Ishiguro, Yuriko Kawakami, Yumei Li
Publikováno v:
Congenital Anomalies. 51:55-61
We found that repeated treatment with phenobarbital (PB), a thyroid modulator, resulted in a persistent estrous stage in the present study. Although the effects of PB in blocking the surge release of luteinizing hormone (LH), inducing anovulation and
Autor:
Toshinao Goda, Yutaro Tanaka, Masahiro Fuchigami, Kazuki Mochizuki, Toshihiko Kumazawa, Nanae Fukaya, Zhu Jiuxin
Publikováno v:
European Journal of Pharmacology. 624:51-57
The Otsuka Long-Evans Tokushima Fatty (OLETF) rat, an animal model of type 2 diabetes, exhibits obesity, hyperglycemia and hyperlipidemia, with late onset of chronic and slowly progressive hyperinsulinemia. In this study, we examined effects of long-
Autor:
Shigeru Hisada, Shinichi Komatsu, Satoshi Kudo, Toshihiko Kumazawa, Yasuo Ohno, Masayuki Ube, Midori Yoshida, Atsushi Sanbuissho, Fumio Sagami
Publikováno v:
The Journal of Toxicological Sciences. 34:S1-S22
The National Institute of Health Sciences (NIHS) and 18 pharmaceutical companies of the Japan Pharmaceutical Manufacturers Association (JPMA) have conducted a validation study intended to evaluate whether a 2-week repeated general toxicity period wit
Autor:
Zhu Jiuxin, Satoko Harada, Yoshiaki Tagawa, Toshihiko Kumazawa, Hiromi Nishitani, Tsukasa Ishiguro, Takashi Tanaharu, Yukiko Inoue, Ikuo Hayasaka, Atsushi Nakajima
Publikováno v:
The Journal of Toxicological Sciences. 34:S157-S165
The main focus of this study is to determine the optimal administration period concerning toxic effects on ovarian morphological changes in a repeated-dose toxicity study. To assess morphological and functional changes induced in the ovary by bromocr
Autor:
Toshihiko Kumazawa, Kiyoshi Haruyama, Shoji Fukushima, Yoshiaki Tagawa, Kazuhito Ichikawa, Hisakazu Iwai
Publikováno v:
Journal of Toxicologic Pathology. 13:7-11
To assess the morphological changes of the lacrimal gland after cholinergic suppression, we performed light- and transmission-electron microscopic examinations on the exorbital lacrimal glands in rats after intragastric intubation of atropine, a nons