Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Toshihiko KANZAKI"'
Publikováno v:
Journal of the agricultural chemical society of Japan. 65:737-746
(1) Brevibacterium thiogenitalisから誘導されたオレイン酸要求株D-248をビオチン過剰(150μg/l以上)存在下で,グルコースと酢酸をモル比で1:2に混合して培養すると,グルタミン酸蓄積量が顕著に向上
Autor:
Toshihiko Kanzaki, Yukio Fujisawa
Publikováno v:
Agricultural and Biological Chemistry. 39:2043-2048
Existence of an acetyltransferase, which catalizes acetylation of deacetylcephalosporin C to cephalosporin C, was demonstrated for the first time in cell-free extracts of Cephalosporium acremonium. The pH optimum of the enzyme appeared to be 7.0 to 7
Publikováno v:
Agricultural and Biological Chemistry. 43:155-160
Publikováno v:
Agricultural and Biological Chemistry. 39:2049-2055
Publikováno v:
Agricultural and Biological Chemistry. 39:2049-2055
Deacetylcephalosporin C negative mutants, lacking a certain step in the pathway of deacetylcephalosporin C biosynthesis, were obtained from the deacetylcephalosporin C producing mutant No. 40 of Cephalosporium acremonium by treatment with N-methyl-N
Publikováno v:
Agricultural and Biological Chemistry. 39:1303-1309
Autor:
Masahiko Yoneda, Kiyoshi Nara, Yukio Fujisawa, Hideo Shirafuji, Makoto Kida, Toshihiko Kanzaki
Publikováno v:
Agricultural and Biological Chemistry. 39:1295-1301
Cephalosporin C negative mutants, lacking a certain step in the pathway of cephalosporin C biosynthesis, were obtained from Cephalosporium acremonium ATCC 14553 by treatment with N-methyl-N′-nitro-N-nitrosoguanidine. Among these mutants, the strain
Autor:
Yukio Fujisawa, Toshihiko Kanzaki
Publikováno v:
Agricultural and Biological Chemistry. 39:2043-2048
Publikováno v:
Agricultural and Biological Chemistry. 39:1303-1309
Cephalosporin C acetyl-hydrolase, which had not yet been found in Cephalosporium acremonium cultures, was partially purified from the culture fluid of the mutant No. 81 by ammonium sulfate fractionation, dialysis and DEAE-cellulose column chromatogra
Publikováno v:
Agricultural and Biological Chemistry. 43:155-160
The two β-lactam antibiotics produced by Cephalosporium acremonium ATCC 14553, cephalosporin C and penicillin N, have been proposed to be biosynthesized through the peptide, δ-(l-α-aminoadipyl)-l-cystemyl-d-valine.Many β-lactam negative mutants w